| Protein Name: | Triosephosphate isomerase (P60174) |
|---|---|
| Gene Name: | TPI1 |
| Description: | Triosephosphate isomerase (EC 5 3 1 1) (TIM) (Triose-phosphate isomerase) |
| PDB ID: | 1HTI |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zalcitabine | Cardiotoxicity | ddC treatment induced a skeletal muscle-specific decrease in the quantity of triosephosphate isomerase@which suggests that the short term cardiotoxicity of ddC is partially based on ROS-mediated signalling [ ADR Type 5 ] | Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions |
This panel provides information on drug category
| Toxicity | Source |
|---|