InAADR

Protein Information

Protein Name: Sodium channel protein type 1 subunit alpha (P35498)
Gene Name: SCN1A
Description:
PDB ID:
Protein Family: PF00520
Protein Category: Ion Channels

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference

This panel provides information on drug category

Toxicity Source
Agitation Large-scale prediction and testing of drug activity on side-effect targets
Apnoea Large-scale prediction and testing of drug activity on side-effect targets
Cardiac Arrest Large-scale prediction and testing of drug activity on side-effect targets
Central Nervous System Stimulation Large-scale prediction and testing of drug activity on side-effect targets
Coma Large-scale prediction and testing of drug activity on side-effect targets
Convulsion Large-scale prediction and testing of drug activity on side-effect targets
Corneal Disorder Large-scale prediction and testing of drug activity on side-effect targets
Death Large-scale prediction and testing of drug activity on side-effect targets
Dysarthria Large-scale prediction and testing of drug activity on side-effect targets
Encephalopathy Large-scale prediction and testing of drug activity on side-effect targets
Epilepsy Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation
Febrile Seizures A splice site variant in the sodium channel gene SCN1A confers risk of febrile seizures
Foetal Damage Large-scale prediction and testing of drug activity on side-effect targets
Hypoaesthesia Oral Large-scale prediction and testing of drug activity on side-effect targets
Impaired Healing Large-scale prediction and testing of drug activity on side-effect targets
Keratitis Large-scale prediction and testing of drug activity on side-effect targets
Loss Of Consciousness Large-scale prediction and testing of drug activity on side-effect targets
Methaemoglobinaemia Large-scale prediction and testing of drug activity on side-effect targets
Muscle Twitching Large-scale prediction and testing of drug activity on side-effect targets
Myocardial Depression Large-scale prediction and testing of drug activity on side-effect targets
Myoclonic Seizures Frequent mutations of SCN1A in severe myoclonic epilepsy in infancy
Nervousness Large-scale prediction and testing of drug activity on side-effect targets
Presyncope Large-scale prediction and testing of drug activity on side-effect targets
Respiratory Failure Large-scale prediction and testing of drug activity on side-effect targets
Seizures Idiopathic epilepsies with seizures precipitated by fever and SCN1A abnormalities
Sensitisation Large-scale prediction and testing of drug activity on side-effect targets
Tinnitus Large-scale prediction and testing of drug activity on side-effect targets
Tremor Large-scale prediction and testing of drug activity on side-effect targets
Vasodilatation Large-scale prediction and testing of drug activity on side-effect targets
Vision Blurred Large-scale prediction and testing of drug activity on side-effect targets
Visual Pathway Disorder Large-scale prediction and testing of drug activity on side-effect targets

InAADR: Drug-Protein-ADRs database