InAADR

Protein Information

Protein Name: Talin (Q9Y490)
Gene Name: TLN1
Description: Talin-1
PDB ID: 1SYQ
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Estradiol Cells To Form Multilayers Vinculin- and talin-rich cell-matrix adhesion plaques were reduced in overall number and size in confluent and postconfluent cultures@SO the gradual loss of vinculin from cell-matrix and cell-cell adherens junctions of the monolayer could be a potential factor in the capacity of these cells to form multilayers or nodules in postconfluent growth. [ ADR Type 2 ] 17-beta-Estradiol induced alterations of cell-matrix and intercellular adhesions in a human mammary carcinoma cell line

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database