| Protein Name: | UDP-glucuronyltransferase (Q64550) |
|---|---|
| Gene Name: | Ugt1a1 |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Selective Effect Of A P-Chlorophenyl Moiety | Indomethacin in vitro also caused a loss of cytochrome b5@ NADH-cytochrome b5 reductase@ NADPH-cytochrome c reductase and epoxide hydrolase activities@ but an activation of UDP-glucuronyltransferase@which leads to selective effect of a p-chlorophenyl moiety [ ADR Type 1 ] | Denaturation of cytochrome P-450 by indomethacin and other non-steroidal anti-inflammatory drugs: evidence for a surfactant mechanism and a selective effect of a p-chlorophenyl moiety |
This panel provides information on drug category
| Toxicity | Source |
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