InAADR

Protein Information

Protein Name: TNF receptor-associated factor 1 (Q13077)
Gene Name: TRAF1
Description: TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
PDB ID: 3M0D
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Bryostatin 1 Apoptosis Paclitaxel-induced apoptosis of breast cancer cells Expression of the anti-apoptotic tumor necrosis factor receptor associated factor 1 (TRAF1) and defender-against cell death (DAD-1) is regulated by NF-kappaB in certain breast cancer cells [ ADR Type 2 ] Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor
Paclitaxel Apoptosis Of Breast Cancer Cells Expression of the anti-apoptotic tumor necrosis factor receptor associated factor 1 (TRAF1) and defender-against cell death (DAD-1) is regulated by NF-kappaB in certain breast cancer cells@which increases paclitaxel-induced apoptosis of breast cancer cells. [ ADR Type 2 ] Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database