InAADR: Drug-Protein-ADRs database

InAADR

Enter Protein Name or Uniprot ID:

Protein Information

Protein Name:	Potassium voltage-gated channel subfamily KQT member 3 (O43525)
Gene Name:	KCNQ3
Description:
PDB ID:
Protein Family:	PF00520
Protein Category:	Ion Channels

Drug-Protein Interaction
Adverse Drug Reactions

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs	Toxicity	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source
Convulsions	Benign familial neonatal convulsions caused by altered gating of KCNQ2/KCNQ3 potassium channels
Epilepsy	A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons
Seizures	Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization

InAADR: Drug-Protein-ADRs database