InAADR

Protein Information

Protein Name: Phospholipase A (P04054)
Gene Name: PLA2G1B
Description: Phospholipase A2 precursor (EC 3 1 1 4) (Phosphatidylcholine 2- acylhydrolase) (Group IB phospholipase A2)
PDB ID: 1YSK
Protein Family:
Protein Category: Enzyme

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Amikacin Aminoglycoside Toxicity Amikacin inhibited both phospholipase A and phospholipase C,which is possible mechanism of aminoglycoside toxicity. [ ADR Type 1 ] Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity
Dibekacin Aminoglycoside Toxicity Dibekacin inhibited both phospholipase A and phospholipase C,which is a possible mechanism of aminoglycoside toxicity. [ ADR Type 1 ] Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity
Gentamicin Aminoglycoside Toxicity Gentamicin inhibited both phospholipase A and phospholipase C,which is a possible mechanism of aminoglycoside toxicity. [ ADR Type 1 ] Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity
Tobramycin Aminoglycoside Toxicity Tobramycin inhibited both phospholipase A and phospholipase C,which is a possible mechanism of aminoglycoside toxicity [ ADR Type 1 ] Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database