This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs |
Toxicity |
Mechanism |
Reference |
|---|
| Methionine | Platelet Aggregation | Genetic defects such as cystathionine beta-synthase or methylene-tetrahydrofolate reductase may contribute to increasing plasma homocysteine levels@which could lead to the pathogenesis of Hcy(formed by demethylation of methionine)-induced vascular damage may be multifactorial@ including direct Hcy damage to the endothelium@ stimulation of proliferation of smooth muscle cells@ enhanced low-density lipoprotein peroxidation@ increase of platelet aggregation@ and effects on the coagulation system. [ ADR Type 3 ] | Hyperhomocysteinemia: atherothrombosis and neurotoxicity
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This panel provides information on drug category