| Protein Name: | Albumin (P23110) |
|---|---|
| Gene Name: | Not Available |
| Description: | Albumin-8 precursor (Methionine-rich 2S protein) (SFA8) |
| PDB ID: | 1S6D |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Ribavirin | Affect Hepatic Functions | Ribavirin was found to inhibit both the synthesis and secretion of albumin in a time- and dose-dependent fashion Such an effect was confirmed by the measurement of albumin and haptoglobin secretion rates@which can directly affect hepatic functions in vitro [ ADR Type 1 ] | Ribavirin inhibits protein synthesis and cell proliferation induced by mitogenic factors in primary human and rat hepatocytes |
| sulfamethoxazole | Agranulocytosis | Binding to albumin increased by the presence of chloride@suggestting that N-chlorosulfamethoxazole may be one of several reactive metabolites of sulfamethoxazole that covalently bind to neutrophil@which is responsible for agranulocytosis. [ ADR Type 2 ] | N-chlorination of sulfamethoxazole and dapsone by the myeloperoxidase system |
| sulfamethoxazole | Lupus | Binding to albumin increased by the presence of chloride@suggestting that N-chlorosulfamethoxazole may be one of several reactive metabolites of sulfamethoxazole that covalently bind to neutrophil@which is responsible for drug-induced lupus [ ADR Type 2 ] | N-chlorination of sulfamethoxazole and dapsone by the myeloperoxidase system |
This panel provides information on drug category
| Toxicity | Source |
|---|