InAADR

Protein Information

Protein Name: Early growth response protein 1 (egr-1) (P18146)
Gene Name: EGR1
Description: Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225)
PDB ID: 4R2A
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Chloroxine Apoptosis Egr-1 mRNA was induced in a time- and dose-dependent manner@which suggest copper@in the presence of 8-hydroxyquinoline@ was able to induce apoptosis of murine J774 A1 cells in culture [ ADR Type 1 ] Copper-induced apoptosis and immediate early gene expression in macrophages

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database