| Protein Name: | Desmin (P17661) |
|---|---|
| Gene Name: | DES |
| Description: | Desmin |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zalcitabine | Cardiotoxicity | An activation of the nuclear poly-(ADP-ribose) polymerase and an increase in the mono-ADP-ribosylation of glucose-regulated protein and desmin were observed in the cardiac tissue from ddC-treated animals@which suggests that the short term cardiotoxicity of ddC is partially based on ROS-mediated signalling. [ ADR Type 2 ] | Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions |
This panel provides information on drug category
| Toxicity | Source |
|---|