InAADR

Protein Information

Protein Name: Chromogranin B (P05060)
Gene Name: CHGB
Description: Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide]
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This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Reserpine Large Dense Core Vesicles Chromogranin B mRNA were increased in the dorsal raphe and in the substantia nigra compacta@which stimulated neurons and leads to an increased synthesis of secretory peptides and consequently to large dense core vesicles filled with higher quanta of peptides. [ ADR Type 1 ] Reserpine causes differential changes in the mRNA levels of chromogranin B, secretogranin II, carboxypeptidase H, alpha-amidating monooxygenase, the vesicular amine transporter and of synaptin/synaptophys

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database