InAADR

Protein Information

Protein Name: dopaminergic receptors (P00014)
Gene Name: Not Available
Description:
PDB ID:
Protein Family:
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This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Haloperidol Detrimental Side Effects Three days of haloperidol administration dramatically decreased BDNF immunostaining in the neurons ,showing that blockade of dopaminergic receptors with haloperidol rapidly downregulates BDNF in reward and emotional centers of the brain,which leads to the efficacious or detrimental side effects of classical neuroleptic drugs. [ ADR Type 5 ] Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database