| Protein Name: | cytochrome P-450-dependent mixed-function oxidase (P00011) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
| PDB ID: | |
| Protein Family: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Mitoxantrone | Oxidative Damage | Mitozantrone inhibites cytochrome P-450-dependent mixed-function oxidase activity, which leads to generation of reactive oxygen species and in oxidative damage [ ADR Type 1 ] | The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells |
This panel provides information on drug category
| Toxicity | Source |
|---|---|
| Oxidative Damage | The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells |