| Protein Name: | c-inhibitor of apoptosis 2 (c-IAP2) (P00008) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Paclitaxel | Apoptosis Of Breast Cancer Cells | Constitutive activation of NF-kappaB leads to overexpression of the anti-apoptotic genes c-inhibitor of apoptosis 2 (c-IAP2) and manganese superoxide dismutase (Mn-SOD) in breast cancer cells,which increase paclitaxel-induced apoptosis of breast cancer cells. [ ADR Type 2 ] | Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor |
This panel provides information on drug category
| Toxicity | Source |
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