| Protein Name: | Catechol O-methyltransferase (P21964) |
|---|---|
| Gene Name: | COMT |
| Description: | Catechol O-methyltransferase (EC 2116) |
| PDB ID: | 3A7E |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Levodopa | Toxicity Of Levodopa | Catechol-O-methyltransferase attenuates toxicity of levodopa in vitro by its metabolism to nontoxic 3-O-methyldopa. [ ADR Type 1 ] | Catechol-O-methyltransferase decreases levodopa toxicity in vitro |
This panel provides information on drug category
| Toxicity | Source |
|---|