InAADR

Drug Information

Drug Name: sofalcone (64506-49-6)
PubChem ID: 5282219
SMILES: CC(=CCOC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
InchiKey: GFWRVVCDTLRWPK-KPKJPENVSA-N
Therapeutic Category: Anti-Ulcer Agents, Gastrointestinal Agents

Computed Drug Properties

Molecular Weight (dalton): 450.531
LogP: 5.7361
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 82.06

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Faeces MetaADEDB
Acidosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Prerenal Failure MetaADEDB
Adh Inappropriate MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Anhidrosis MetaADEDB
Apathy MetaADEDB
Appendicitis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Automatism MetaADEDB
Bacteraemia MetaADEDB
Bacteria Stool Identified MetaADEDB
Bacterial Infection MetaADEDB
Bile Duct Obstruction MetaADEDB
Black Stools MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Elastase Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Fracture MetaADEDB
Bradycardia MetaADEDB
Brain Contusion MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calculus Bladder MetaADEDB
Calculus Ureteric MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Failure MetaADEDB
Cartilage Development Disorder MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerebrovascular Spasm MetaADEDB
Chill MetaADEDB
Cholangiolitis MetaADEDB
Clostridium Colitis MetaADEDB
Cold Sweat MetaADEDB
Colitis Ischaemic MetaADEDB
Coma MetaADEDB
Convulsion MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Device Related Infection MetaADEDB
Disease Of Liver MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Duodenal Ulcer MetaADEDB
Emesis MetaADEDB
Encephalitis Allergic MetaADEDB
Enlarged Liver MetaADEDB
Excoriation MetaADEDB
Gastric Mucosal Lesion MetaADEDB
Gastroenteritis MetaADEDB
Globulinuria MetaADEDB
Gout MetaADEDB
Haemodialysis MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Acute MetaADEDB
Hydrocephalus MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Ild MetaADEDB
Increased White Blood Cell Count MetaADEDB
Kidney Failure MetaADEDB
Knee Arthroplasty MetaADEDB
Large Intestine Perforation MetaADEDB
Lipase MetaADEDB
Lyell MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Meningitides MetaADEDB
Micturition Disorder MetaADEDB
Middle Ear Inflammation MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Nasopharyngitis MetaADEDB
Nephrolithiasis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Paronychia MetaADEDB
Periarthritis MetaADEDB
Peritonitis MetaADEDB
Pleural Effusion MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Chlamydial MetaADEDB
Prothrombin Level Decreased MetaADEDB
Prothrombin Time MetaADEDB
Pulmonary Hypertension MetaADEDB
Pyelonephritis MetaADEDB
Pyelonephritis Acute MetaADEDB
Quadriplegia MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Rate Increased MetaADEDB
Right Heart Failure MetaADEDB
Ruptured Cerebral Aneurysm MetaADEDB
Saliva Discolouration MetaADEDB
Septic Shock MetaADEDB
Shock Haemorrhagic MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Surgery MetaADEDB
Toxic Skin Eruption MetaADEDB
Tuberculous Pleurisy MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Vasospasm MetaADEDB
Vertebral Artery Occlusion MetaADEDB

InAADR: Drug-Protein-ADRs database