InAADR

Drug Information

Drug Name: simethicone (8050-81-5)
PubChem ID: 6433516
SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
InchiKey: AMTWCFIAVKBGOD-UHFFFAOYSA-N
Therapeutic Category: Antifoaming Agents, Dermatologic Agents, Emollients, Surface-Active Agents

Computed Drug Properties

Molecular Weight (dalton): 238.464
LogP: 1.5677
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 52.6

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Mammogram MetaADEDB
Abnormal Movements MetaADEDB
Accident MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Actinic Keratosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Graft Versus Host Disease MetaADEDB
Acute Graft Versus Host Disease In Liver MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Sinusitis MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Afib MetaADEDB
Agitated MetaADEDB
Alcoholism MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Rhinitis MetaADEDB
Amnesia MetaADEDB
Amyotrophy MetaADEDB
Anaemia MetaADEDB
Anal Fissure MetaADEDB
Anal Sphincterotomy MetaADEDB
Angina Unstable MetaADEDB
Anhidrosis MetaADEDB
Anion Gap Decreased MetaADEDB
Anorexia MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Valve Calcification MetaADEDB
Apoplexy MetaADEDB
Application Site Dermatitis MetaADEDB
Application Site Pustules MetaADEDB
Application Site Rash MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis MetaADEDB
Ascites MetaADEDB
Aspiration Bronchial MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia MetaADEDB
Asthma MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Flutter MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Av Dissociation MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Benign Gastric Neoplasm MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bile Duct Stone MetaADEDB
Bipolar Disorder MetaADEDB
Bladder Disorder MetaADEDB
Bladder Repair MetaADEDB
Bladder Retention MetaADEDB
Bleeding Vaginal MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Cholesterol Abnormal MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Sodium MetaADEDB
Body Temperature Increased MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Operation MetaADEDB
Bone Pain MetaADEDB
Bone Spur MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Bradycardia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Breast Discharge MetaADEDB
Breast Lump MetaADEDB
Breast Pain MetaADEDB
Breast Tenderness MetaADEDB
Bronchitis MetaADEDB
Bronchopneumonia MetaADEDB
Bulbar Palsy MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation MetaADEDB
Caesarean Section MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Cardiospasm MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carpal Tunnel MetaADEDB
Cellulitis MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cerebral Arteriosclerosis MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cervicalgia MetaADEDB
Chest Pain MetaADEDB
Child Abuse MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Cholecystitis Acute MetaADEDB
Cholecystitis Chronic MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cognitive Disorder MetaADEDB
Colitis MetaADEDB
Colpitis MetaADEDB
Compression Fracture MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Conjunctival Deposit MetaADEDB
Constipated MetaADEDB
Contact Dermatitis MetaADEDB
Costochondritis MetaADEDB
Cough MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Cystitis Interstitial MetaADEDB
Debridement MetaADEDB
Decreased Interest MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Operation MetaADEDB
Dentofacial Anomaly MetaADEDB
Device Failure MetaADEDB
Device Leakage MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Gastroparesis MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Difficulty In Walking MetaADEDB
Dilatation Ventricular MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Dizziness MetaADEDB
Dizziness Exertional MetaADEDB
Drug Abuser MetaADEDB
Drug Addict MetaADEDB
Drug Screen Positive MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Duodenal Ulcer MetaADEDB
Duodenitis MetaADEDB
Dysmenorrhea MetaADEDB
Dyspepsia MetaADEDB
Dyspnea Exertional MetaADEDB
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Dysuria MetaADEDB
Ear Ache MetaADEDB
Economic Problem MetaADEDB
Ectopic Pregnancies MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Electrocardiogram St-T Change MetaADEDB
Electrolyte Disorder MetaADEDB
Embolic Stroke MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalopathy MetaADEDB
Endodontic Procedure MetaADEDB
Endotracheal Intubation MetaADEDB
Engraftment Syndrome MetaADEDB
Enteritis MetaADEDB
Enterobacter Bacteraemia MetaADEDB
Enterocolitis Infectious MetaADEDB
Eosinophil Count Decreased MetaADEDB
Eosinophil Count Increased MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction MetaADEDB
Erosive Gastritis MetaADEDB
Eruption MetaADEDB
Erythema Migrans MetaADEDB
Esophageal Rupture MetaADEDB
Esophageal Stenosis MetaADEDB
Excess Potassium MetaADEDB
Exercise Tolerance Decreased MetaADEDB
Exposure To Toxic Agent MetaADEDB
External Ear Infection MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Faeces Discoloured MetaADEDB
Failure To Thrive MetaADEDB
Fallopian Tube Operation MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia MetaADEDB
Fibroids MetaADEDB
Fibrous Histiocytoma MetaADEDB
Flatulence MetaADEDB
Fluid Overload MetaADEDB
Galactorrhea MetaADEDB
Gangrene MetaADEDB
Gastric Disorder MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastroduodenitis MetaADEDB
Gastroenteritis MetaADEDB
Gastroenteritis Radiation MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Perforation MetaADEDB
Gingival Erythema MetaADEDB
Globulinuria MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulosclerosis MetaADEDB
Glucose Urine MetaADEDB
Gout MetaADEDB
Granulocytosis MetaADEDB
Haemangioma Of Skin MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haemolysis MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Haemorrhoid Operation MetaADEDB
Haemorrhoids MetaADEDB
Head Injury MetaADEDB
Heart Rate Increased MetaADEDB
Heart Valve Incompetence MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Vein Thrombosis MetaADEDB
Hepatojugular Reflux MetaADEDB
Hernia Hiatal MetaADEDB
High Blood Pressure MetaADEDB
Hodgkin Disease MetaADEDB
Hypercalcaemia Of Malignancy MetaADEDB
Hyperlipaemia MetaADEDB
Hypertonia MetaADEDB
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypokalaemia MetaADEDB
Hypokinesia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypothyroid MetaADEDB
Immunodeficiency MetaADEDB
Impaired Healing MetaADEDB
Increased Appetite MetaADEDB
Infection MetaADEDB
Infection Susceptibility Increased MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Infusion Related Reaction MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Mass MetaADEDB
Injection Site Nodule MetaADEDB
Injection Site Stinging MetaADEDB
Intention Tremor MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Functional Disorder MetaADEDB
Intestinal Obstruction MetaADEDB
Intestinal Perforation MetaADEDB
Intracranial Aneurysm MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Irritable Bowel Syndrome MetaADEDB
Joint Sprain MetaADEDB
Jugular Vein Distension MetaADEDB
Kidney Failure MetaADEDB
Lactose Intolerance MetaADEDB
Large Intestine Perforation MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Lethargy MetaADEDB
Leukopenia Neonatal MetaADEDB
Life Expectancy Shortened MetaADEDB
Light Chain Analysis Increased MetaADEDB
Liver Transplant Rejection MetaADEDB
Loss Of Weight MetaADEDB
Lumbar Radiculopathy MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Malnourished MetaADEDB
Mastication Disorder MetaADEDB
Mechanical Ventilation MetaADEDB
Medication Residue MetaADEDB
Meningitis Enterococcal MetaADEDB
Meniscus Lesion MetaADEDB
Menometrorrhagia MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Artery Stenosis MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine MetaADEDB
Mitral Valve Stenosis MetaADEDB
Mixed Connective Tissue Disease MetaADEDB
Mouth Pain MetaADEDB
Mucosal Inflammation MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Musculoskeletal Pain MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myelopathy MetaADEDB
Nasal Congestion MetaADEDB
Nausea MetaADEDB
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neurogenic Bowel MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutrophil Count Abnormal MetaADEDB
No Adverse Drug Effect MetaADEDB
Nocturia MetaADEDB
Odynophagia MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oesophagogastroduodenoscopy MetaADEDB
Oral Herpes MetaADEDB
Oral Intake Reduced MetaADEDB
Organic Erectile Dysfunction MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteolysis MetaADEDB
Osteopenia MetaADEDB
Ovarian Mass MetaADEDB
Overweight MetaADEDB
Pain MetaADEDB
Pain Pelvic MetaADEDB
Pancreatitis Chronic MetaADEDB
Pathogen Resistance MetaADEDB
Pedal Pulse Absent MetaADEDB
Pericardial Fibrosis MetaADEDB
Perineal Operation MetaADEDB
Periodontal Operation MetaADEDB
Peritoneal Effusion MetaADEDB
Peritonitis Bacterial MetaADEDB
Pharyngeal Haematoma MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebothrombosis MetaADEDB
Photosensitive Rash MetaADEDB
Physical Examination Abnormal MetaADEDB
Plasmacytoma MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleural Neoplasm MetaADEDB
Pneumomediastinum MetaADEDB
Pneumonia Fungal MetaADEDB
Pneumopericardium MetaADEDB
Pneumoperitoneum MetaADEDB
Pneumothorax MetaADEDB
Portal Hypertension MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Procedural Pain MetaADEDB
Protein Total Decreased MetaADEDB
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Radiation Oesophagitis MetaADEDB
Radius Fracture MetaADEDB
Rectal Polypectomy MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Tract Congestion MetaADEDB
Rhinorrhea MetaADEDB
Right Atrial Dilatation MetaADEDB
Risus Sardonicus MetaADEDB
Road Traffic Accident MetaADEDB
Scar MetaADEDB
Schizophrenia Undifferentiated Type MetaADEDB
Sensation Of Foreign Body MetaADEDB
Sensory Disturbance MetaADEDB
Septic Shock MetaADEDB
Sequestrectomy MetaADEDB
Serratia Bacteraemia MetaADEDB
Shoulder Pain MetaADEDB
Sinusitis MetaADEDB
Skin Laceration MetaADEDB
Sleep Apnea MetaADEDB
Small Intestinal Obstruction MetaADEDB
Somatisation Disorder MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Deformity MetaADEDB
Spinal Disorder MetaADEDB
Spinal Osteoarthritis MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Streptococcal Bacteraemia MetaADEDB
Stridor MetaADEDB
Substance Abuse MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Syncope Vasovagal MetaADEDB
Systemic Candida MetaADEDB
Tachycardia Ventricular MetaADEDB
Tearfulness MetaADEDB
Throat Tightness MetaADEDB
Tongue Dry MetaADEDB
Tooth Fracture MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Ulcer MetaADEDB
Umbilical Cord Abnormality MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urge Incontinence MetaADEDB
Urinary Tract Disorder MetaADEDB
Urine Analysis Abnormal MetaADEDB
Vena Cava Thrombosis MetaADEDB
Violence-Related Symptom MetaADEDB
Visual Disturbance MetaADEDB
Vitamin B12 Increased MetaADEDB
Vulval Disorder MetaADEDB
Warm Type Haemolytic Anaemia MetaADEDB
Weight Fluctuation MetaADEDB
Weight Gain MetaADEDB
Weight Loss Poor MetaADEDB
Wound MetaADEDB
Wound Infection MetaADEDB
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database