InAADR

Drug Information

Drug Name: roxithromycin (80214-83-1)
PubChem ID: 122172998
SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](/C(=NOCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@@H]2C[C@@]([C@@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@@H](C[C@@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InchiKey: RXZBMPWDPOLZGW-AGSCYWRJSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 837.058
LogP: 2.2096
Ring Count: 0
Hydrogen Bond Acceptor Count: 17
Hydrogen Bond Donor Count: 5
Total Polar Surface Area: 216.89

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Accommodation Disorder MetaADEDB
Aching Muscles MetaADEDB
Acidosis MetaADEDB
Acquired Haemophilia MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anemia Hemolytic Autoimmune MetaADEDB
Angiitis MetaADEDB
Angioedema MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anorexia MetaADEDB
Arteriovenous Fistula Site Haemorrhage MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Atrial Hypertrophy MetaADEDB
Attempted Suicide MetaADEDB
Back Ache MetaADEDB
Bile Duct Obstruction MetaADEDB
Biopsy Kidney MetaADEDB
Bladder Inflammation MetaADEDB
Bleb MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Electrolytes Abnormal MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Body Temperature Increased MetaADEDB
Brain Death MetaADEDB
Brain Oedema MetaADEDB
Breast Oedema MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchitis MetaADEDB
Bronchitis Bacterial MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Calculus Urinary MetaADEDB
Cancer MetaADEDB
Carcinoma Hepatocellular MetaADEDB
Cardiac Failure MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cervix Operation MetaADEDB
Chest Infection MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Choking MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Respiratory Failure MetaADEDB
Churg-Strauss Syndrome MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cmv Infection MetaADEDB
Coagulation Time Prolonged MetaADEDB
Colitis MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Cough MetaADEDB
Coughing Blood MetaADEDB
Crackles Lung MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Cryptococcosis MetaADEDB
Cryptosporidiosis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Dehydration MetaADEDB
Dental Fistula MetaADEDB
Dental Pain MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatomyositis MetaADEDB
Disorder Lung MetaADEDB
Disseminated Tuberculosis MetaADEDB
Dizziness MetaADEDB
Drug Eruptions MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dyspnoea Exacerbated MetaADEDB
Electrolyte Disorder MetaADEDB
Electromechanical Dissociation MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Empyema MetaADEDB
Encephalitis Allergic MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epidermal Growth Factor Receptor Increased MetaADEDB
Epistaxis MetaADEDB
Erysipelas MetaADEDB
Erythema Multiforme MetaADEDB
Exanthema MetaADEDB
Excess Potassium MetaADEDB
Eye Oedema MetaADEDB
Eye Operation MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Gallbladder Perforation MetaADEDB
Gamma-Glutamyltransferase MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Operation MetaADEDB
Genital Erosion MetaADEDB
Goiter MetaADEDB
Haematoma MetaADEDB
Haemodynamic Instability MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Veno-Occlusive Disease MetaADEDB
Hepatitis MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Zoster Ophthalmic MetaADEDB
Hiv Wasting Syndrome MetaADEDB
Hydroureter MetaADEDB
Hyperlipaemia MetaADEDB
Hyperreflexia MetaADEDB
Ild MetaADEDB
Impetigo MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Urinary Tract MetaADEDB
Inflammation MetaADEDB
Intentional Misuse MetaADEDB
Interstitial Nephritis MetaADEDB
Jaundice MetaADEDB
Joint Sprain MetaADEDB
Large Intestine Perforation MetaADEDB
Laryngeal Dyspnoea MetaADEDB
Laryngospasm MetaADEDB
Laryngotracheitis MetaADEDB
Leucopenia MetaADEDB
Limb Operation MetaADEDB
Lip Erosion MetaADEDB
Livedo Reticularis MetaADEDB
Liver Failure Acute MetaADEDB
Low Cardiac Output Syndrome MetaADEDB
Lung Diseases MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infection MetaADEDB
Lung Infiltration MetaADEDB
Lyell MetaADEDB
Lymphedema MetaADEDB
Lymphocele MetaADEDB
Lymphocytes Decreased MetaADEDB
Macular Oedema MetaADEDB
Maternal Condition Affecting Foetus MetaADEDB
Metastatic Renal Cell Carcinoma MetaADEDB
Mucous Membrane Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Inflammation MetaADEDB
Muscle Necrosis MetaADEDB
Muscular Diseases MetaADEDB
Mycobacterium Avium Complex Infection MetaADEDB
Myoglobin Blood Increased MetaADEDB
Nail Discolouration MetaADEDB
Nausea MetaADEDB
Neumonia MetaADEDB
Nikolsky Sign MetaADEDB
Nonspecific Reaction MetaADEDB
Obliterative Bronchiolitis MetaADEDB
Olfaction Disorders MetaADEDB
Onychoclasis MetaADEDB
Optic Neuropathy MetaADEDB
Oral Mucosa Erosion MetaADEDB
Osteomyelitis MetaADEDB
Pain In Throat MetaADEDB
Pallor MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Pleural Effusion MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Polyuria MetaADEDB
Primary Sequestrum MetaADEDB
Productive Cough MetaADEDB
Prothrombin Level Decreased MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulse Pressure Decreased MetaADEDB
Purulence MetaADEDB
Rales MetaADEDB
Renal Insufficiency MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Rate Increased MetaADEDB
Resuscitation MetaADEDB
Retinal Vascular Occlusion MetaADEDB
Rhabdomyolysis MetaADEDB
Sepsis Syndrome MetaADEDB
Skin Desquamation MetaADEDB
Small Intestinal Obstruction MetaADEDB
Sputum Culture Positive MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Tachycardia MetaADEDB
Torsades De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Transaminases Increased MetaADEDB
Urticaria MetaADEDB
Vaginal Contraceptive Device Expelled MetaADEDB
Vascular Diseases MetaADEDB
Venoocclusive Liver Disease MetaADEDB
Vulvar Erosion MetaADEDB
Wound Treatment MetaADEDB

InAADR: Drug-Protein-ADRs database