InAADR

Drug Information

Drug Name: etizolam (40054-69-1)
PubChem ID: 3307
SMILES: CCC1=CC2=C(S1)N3C(=NN=C3CN=C2C4=CC=CC=C4Cl)C
InchiKey: VMZUTJCNQWMAGF-UHFFFAOYSA-N
Therapeutic Category: Central Nervous System Agents, Central Nervous System Depressants, Psychotropic Drugs, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 342.855
LogP: 4.20402
Ring Count: 3
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 43.07

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abnormal Behaviour MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abscess Management MetaADEDB
Abulia MetaADEDB
Acarodermatitis MetaADEDB
Aching Muscles MetaADEDB
Acquired Epidermolysis Bullosa MetaADEDB
Activation Syndrome MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agnosia MetaADEDB
Agranulocytoses MetaADEDB
Akinesia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Liver Disease MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergy To Metals MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Anaemia Hypochromic MetaADEDB
Anaesthesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Anemia Aplastic MetaADEDB
Anorectal Disorder MetaADEDB
Anorexia MetaADEDB
Anterograde Amnesia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anti-Insulin Antibody Positive MetaADEDB
Anti-Platelet Antibody Positive MetaADEDB
Antibody Test Abnormal MetaADEDB
Aortic Dissection MetaADEDB
Apallic Syndrome MetaADEDB
Apathy MetaADEDB
Apnea MetaADEDB
Appendicitis MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Artery Dissection MetaADEDB
Ascites MetaADEDB
Aseptic Meningitis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Aspiration Pneumonia MetaADEDB
Atrial Natriuretic Peptide Increased MetaADEDB
Atrioventricular Block Complete MetaADEDB
Attempted Suicide MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Atypical Mycobacterial Infection MetaADEDB
Autism MetaADEDB
Automatism MetaADEDB
Autonomic Instability MetaADEDB
Av Dissociation MetaADEDB
Band Neutrophil Percentage Decreased MetaADEDB
Base Excess Increased MetaADEDB
Basophil Count Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bile Duct Cancer Stage Iii MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Biopsy Colon MetaADEDB
Bipolar I Disorder MetaADEDB
Birth Trauma MetaADEDB
Black Stools MetaADEDB
Bleeding Time Prolonged MetaADEDB
Blepharoptosis MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Aldosterone Increased MetaADEDB
Blood Alkaline Phosphatase Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Cholinesterase MetaADEDB
Blood Creatine Phosphokinase Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Fibrinogen MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Immunoglobulin G Decreased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Product Transfusion Dependent MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Urine Present MetaADEDB
Blood Zinc Decreased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Fracture MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia MetaADEDB
Brain Abscess MetaADEDB
Brain Death MetaADEDB
Brain Stem Syndrome MetaADEDB
Buccal Mucosal Roughening MetaADEDB
Bursitis Infective MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cancer Pain MetaADEDB
Candida Pneumonia MetaADEDB
Candida Serology Positive MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Death MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Insufficiency MetaADEDB
Cardioversion MetaADEDB
Cartilage Development Disorder MetaADEDB
Cataract MetaADEDB
Catheter Placement MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Removal MetaADEDB
Cerebellar Haemangioma MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Circulatory Failure MetaADEDB
Cerebral Disorder MetaADEDB
Cerebral Infarct MetaADEDB
Cheilitis MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Cholangiolitis MetaADEDB
Chromosome Abnormality MetaADEDB
Chronic Active Hepatitis MetaADEDB
Circadian Rhythm Sleep Disorder MetaADEDB
Clavicle Fracture MetaADEDB
Clonus MetaADEDB
Colitis Pseudomembranous MetaADEDB
Colorectal Cancer MetaADEDB
Coma MetaADEDB
Communication Disorder MetaADEDB
Completed Suicide MetaADEDB
Condition Aggravated MetaADEDB
Congenital Central Nervous System Anomaly MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Consciousness Fluctuating MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Contracture MetaADEDB
Contralateral Breast Cancer MetaADEDB
Conversion Disorder MetaADEDB
Coombs Direct Test Positive MetaADEDB
Corneal Oedema MetaADEDB
Coughing Blood MetaADEDB
Crush Syndrome MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Decreased Activity MetaADEDB
Decubitus Ulcer MetaADEDB
Delusion MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressed Mood MetaADEDB
Depression Suicidal MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Developmental Delay MetaADEDB
Diabetes Insipidus MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Diaphragmalgia MetaADEDB
Diet Refusal MetaADEDB
Disease Of Liver MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dissociative Fugue MetaADEDB
Diverticular Fistula MetaADEDB
Diverticular Perforation MetaADEDB
Dizziness MetaADEDB
Drowning MetaADEDB
Drowsiness MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Syndrome Neonatal MetaADEDB
Duodenal Stenosis MetaADEDB
Dyslalia MetaADEDB
Dysstasia MetaADEDB
Dysthymic Disorder MetaADEDB
Dysuria MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Eczema MetaADEDB
Educational Problem MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electroconvulsive Therapy MetaADEDB
Elevated Triglycerides MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
Encephalopathy Hypertensive MetaADEDB
Endometriosis MetaADEDB
Enterocolitis MetaADEDB
Entropion MetaADEDB
Enzyme Abnormality MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epilepsy MetaADEDB
Epstein-Barr Virus Test Positive MetaADEDB
Erotomanic Delusion MetaADEDB
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Exercise Lack Of MetaADEDB
Extensor Plantar Response MetaADEDB
Extrapyramidal Disorder MetaADEDB
Eye Pain MetaADEDB
Eyelid Erosion MetaADEDB
Facial Palsy MetaADEDB
Facial Spasm MetaADEDB
Family Stress MetaADEDB
Fat Embolism MetaADEDB
Feeding Disorder MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Feeding Tube Insertion MetaADEDB
Fibrin D Dimer MetaADEDB
Fibrin Decreased MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Floaters MetaADEDB
Fracture Delayed Union MetaADEDB
Fractured Skull Depressed MetaADEDB
Freezing Phenomenon MetaADEDB
Fungal Sepsis MetaADEDB
Galactorrhea MetaADEDB
Gamma-Glutamyltransferase Abnormal MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastric Lavage MetaADEDB
Gastric Outlet Obstruction MetaADEDB
Gastric Ulcer MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastric Ulcer Perforated MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Amyloidosis MetaADEDB
Gastrointestinal Endoscopic Therapy MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Gastrointestinal Perforation MetaADEDB
Gaze Palsy MetaADEDB
Generalised Erythema MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glossectomy MetaADEDB
Glossoptosis MetaADEDB
Glucose Urine MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Granulocyte Count Decreased MetaADEDB
Grip Strength MetaADEDB
Guttate Psoriasis MetaADEDB
Haematocrit Increased MetaADEDB
Haemodialysis MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Haptoglobin Decreased MetaADEDB
Heart Valve Calcification MetaADEDB
Helicobacter Gastritis MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatic Rupture MetaADEDB
Hepatitis MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis Fulminant MetaADEDB
Hiccough MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hodgkin Disease MetaADEDB
Homicidal Ideation MetaADEDB
Human Herpes Virus 6 Serology Positive MetaADEDB
Hyperacusia MetaADEDB
Hyperalimentation MetaADEDB
Hypercapnia MetaADEDB
Hypercreatininaemia MetaADEDB
Hyperhidrosis MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypertonic Bladder MetaADEDB
Hyperventilation MetaADEDB
Hypervigilance MetaADEDB
Hypoaesthesia MetaADEDB
Hypochondriasis MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Unconsciousness MetaADEDB
Hypokalaemia MetaADEDB
Hypophagia MetaADEDB
Hyporeflexia MetaADEDB
Hypotonia MetaADEDB
Hypotonia Neonatal MetaADEDB
Hypoventilation Neonatal MetaADEDB
Hypovolaemic Shock MetaADEDB
Hypoxia MetaADEDB
Ichthyosis MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Idiosyncratic Alcohol Intoxication MetaADEDB
Ild MetaADEDB
Immunosuppression MetaADEDB
Implant Site Effusion MetaADEDB
Impulsive Behaviour MetaADEDB
Inadequate Diet MetaADEDB
Incisional Hernia MetaADEDB
Increased Appetite MetaADEDB
Increased White Blood Cell Count MetaADEDB
Induration MetaADEDB
Injury Asphyxiation MetaADEDB
Intention Tremor MetaADEDB
Intraocular Lens Implant MetaADEDB
Intrauterine Infection MetaADEDB
Intubation MetaADEDB
Japan Coma Scale Abnormal MetaADEDB
Joint Ankylosis MetaADEDB
Joint Arthroplasty MetaADEDB
Joint Contracture MetaADEDB
Kaposi Sarcoma MetaADEDB
Kyphosis MetaADEDB
Large Intestine Perforation MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Limb Malformation MetaADEDB
Lissencephaly MetaADEDB
Liver Carcinoma Ruptured MetaADEDB
Logorrhoea MetaADEDB
Long Qt Syndrome MetaADEDB
Lumbar Vertebral Fracture MetaADEDB
Lung Edema MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Morphology Abnormal MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Mania MetaADEDB
Mechanical Ventilation MetaADEDB
Megakaryocytes Decreased MetaADEDB
Mental Disorder MetaADEDB
Mental Impairment MetaADEDB
Meralgia Paraesthetica MetaADEDB
Micturition Frequency Decreased MetaADEDB
Middle Ear Inflammation MetaADEDB
Mood Altered MetaADEDB
Moraxella Infection MetaADEDB
Mouth Breathing MetaADEDB
Movement Disorder MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Tightness MetaADEDB
Muscle Weakness MetaADEDB
Muscular Dystrophy MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Mutism MetaADEDB
Myasthenia Gravis MetaADEDB
Myelodysplasia MetaADEDB
Myocardial Fibrosis MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobin Urine MetaADEDB
Myoglobin Urine Present MetaADEDB
Narcotic Intoxication MetaADEDB
Nasopharyngitis MetaADEDB
Necrotising Retinitis MetaADEDB
Neonatal Asphyxia MetaADEDB
Neonatal Respiratory Arrest MetaADEDB
Nephrogenic Anaemia MetaADEDB
Nephrotic Syndrome MetaADEDB
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neuromyelitis Optica MetaADEDB
Neurosis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Normal Delivery MetaADEDB
Obsessive Thoughts MetaADEDB
Ocular Hypertension MetaADEDB
Oedema Mucosal MetaADEDB
Oesophageal Carcinoma Recurrent MetaADEDB
Oliguria MetaADEDB
Open Wound MetaADEDB
Optic Disc Edema MetaADEDB
Optic Neuritis MetaADEDB
Orchidectomy MetaADEDB
Organising Pneumonia MetaADEDB
Oropharyngeal Pain MetaADEDB
Orthopedic Procedure MetaADEDB
Ovarian Cancer MetaADEDB
Ovarian Cancer Recurrent MetaADEDB
Overdose MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitation MetaADEDB
Palsies MetaADEDB
Pancreatic Atrophy MetaADEDB
Paraesthesia Oral MetaADEDB
Parkinson MetaADEDB
Paronychia MetaADEDB
Pemphigus MetaADEDB
Periarthritis MetaADEDB
Pericardial Haemorrhage MetaADEDB
Periodontitis MetaADEDB
Peripheral Nerve Palsy MetaADEDB
Peritonitis MetaADEDB
Persecutory Delusion MetaADEDB
Persistent Foetal Circulation MetaADEDB
Pertussis MetaADEDB
Pharyngeal Inflammation MetaADEDB
Photosensitive Rash MetaADEDB
Physiotherapy MetaADEDB
Pigmentation Disorder MetaADEDB
Platelet Aggregation Inhibition MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pollakiuria MetaADEDB
Polycythaemia MetaADEDB
Polymyositis MetaADEDB
Poor Sucking Reflex MetaADEDB
Poriomania MetaADEDB
Post Procedural Bile Leak MetaADEDB
Postoperative Wound Complication MetaADEDB
Posture Abnormal MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Prinzmetal Angina MetaADEDB
Prostate Cancer Stage Iv MetaADEDB
Protein Total Decreased MetaADEDB
Pseudarthrosis MetaADEDB
Pseudoaldosteronism MetaADEDB
Psychiatric Symptom MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Function Test Increased MetaADEDB
Pulmonary Infarction MetaADEDB
Pupillary Light Reflex Tests Abnormal MetaADEDB
Pyelonephritis MetaADEDB
Pyelonephritis Acute MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Quadriplegia MetaADEDB
Rash Generalised MetaADEDB
Reactive Psychosis MetaADEDB
Rectal Perforation MetaADEDB
Red Blood Cell Count Increased MetaADEDB
Reflux Esophagitis MetaADEDB
Regressive Behaviour MetaADEDB
Reiter Syndrome MetaADEDB
Renal Cancer Stage Iv MetaADEDB
Renal Cyst Infection MetaADEDB
Renal Impairment MetaADEDB
Renin Increased MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Disorder Neonatal MetaADEDB
Resuscitation MetaADEDB
Reticulocyte Count Increased MetaADEDB
Retinal Bleeding MetaADEDB
Retinitis Viral MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinalgia MetaADEDB
Scan With Contrast Abnormal MetaADEDB
Schizophrenia MetaADEDB
Schizophreniform Disorder MetaADEDB
Scotoma MetaADEDB
Secondary Hypothyroidism MetaADEDB
Self Injurious Behaviour MetaADEDB
Self Mutilation MetaADEDB
Sensation Of Heaviness MetaADEDB
Sepsis Syndrome MetaADEDB
Sexual Abuse MetaADEDB
Shock Haemorrhagic MetaADEDB
Shunt Malfunction MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinus Arrest MetaADEDB
Skin Chapped MetaADEDB
Skin Erosion MetaADEDB
Skin Test Positive MetaADEDB
Sleep Phase Rhythm Disturbance MetaADEDB
Sleep Walking MetaADEDB
Small For Dates Baby MetaADEDB
Soliloquy MetaADEDB
Speech Disorder MetaADEDB
Speech Rehabilitation MetaADEDB
Spinal Cord Injury Cervical MetaADEDB
Spleen Congestion MetaADEDB
Splenic Abscess MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stress At Work MetaADEDB
Stress Cardiomyopathy MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subdural Haematoma Evacuation MetaADEDB
Subileus MetaADEDB
Sudden Death MetaADEDB
Supraventricular Tachycardia MetaADEDB
Surfactant Protein Increased MetaADEDB
Tachycardia Ventricular MetaADEDB
Talipes MetaADEDB
Tetany MetaADEDB
Threatened Labour MetaADEDB
Thrombotic Stroke MetaADEDB
Tongue Discolouration MetaADEDB
Tongue Disorder MetaADEDB
Tongue Paralysis MetaADEDB
Tonsillitis MetaADEDB
Toxic Skin Eruption MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urethral Caruncle MetaADEDB
Urine Abnormality MetaADEDB
Urine Calcium Increased MetaADEDB
Urine Ketone Body Present MetaADEDB
Urine Osmolarity Increased MetaADEDB
Urine Output Increased MetaADEDB
Urine Sodium MetaADEDB
Vascular Graft MetaADEDB
Vascular Resistance Systemic Decreased MetaADEDB
Venoocclusive Liver Disease MetaADEDB
Verbal Abuse MetaADEDB
Violence-Related Symptom MetaADEDB
Vital Capacity Decreased MetaADEDB
Vitrectomy MetaADEDB
Water Intoxication MetaADEDB
Wound Complication MetaADEDB
Xanthopsia MetaADEDB

InAADR: Drug-Protein-ADRs database