InAADR

Drug Information

Drug Name: epalrestat (82159-09-9)
PubChem ID: 1549120
SMILES: C/C(=CC1=CC=CC=C1)/C=C2/C(=O)N(C(=S)S2)CC(=O)O
InchiKey: CHNUOJQWGUIOLD-NFZZJPOKSA-N
Therapeutic Category: Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 319.407
LogP: 2.9187
Ring Count: 1
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 57.61

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Acid Reflux MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Consumption MetaADEDB
Alcohol Poisoning MetaADEDB
Alcoholic Liver Disease MetaADEDB
Altered State Of Consciousness MetaADEDB
Anaphylactic Reaction MetaADEDB
Anemia Aplastic MetaADEDB
Anorexia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anti-Insulin Antibody Positive MetaADEDB
Apathy MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthenopia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Bacterial Toxaemia MetaADEDB
Balanitis MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Bladder Cancer MetaADEDB
Bladder Tamponade MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Bruise MetaADEDB
Bundle Branch Block Right MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calcium Metabolism Disorder MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cartilage Development Disorder MetaADEDB
Cellulitis MetaADEDB
Cerebral Infarct MetaADEDB
Cholangiolitis MetaADEDB
Clostridial Infection MetaADEDB
Communication Disorder MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Coronary Artery Restenosis MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressed Mood MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetic Gangrene MetaADEDB
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dry Eye MetaADEDB
Dyslalia MetaADEDB
Dysphoria MetaADEDB
Dyspnea Exertional MetaADEDB
Dysthymic Disorder MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Echocardiogram Abnormal MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Encephalitis Allergic MetaADEDB
Eosinophil Count Increased MetaADEDB
Erythema MetaADEDB
Excess Potassium MetaADEDB
Excoriation MetaADEDB
Eye Pain MetaADEDB
Eyelid Diseases MetaADEDB
Feeling Abnormal MetaADEDB
Femoral Neck Fracture MetaADEDB
Finger Amputation MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastric Operation MetaADEDB
Gastric Ulcer MetaADEDB
Generalised Erythema MetaADEDB
Genital Herpes MetaADEDB
Glucose Urine MetaADEDB
Haemangioma Of Liver MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis Fulminant MetaADEDB
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
Hyperammonaemia MetaADEDB
Hypoaesthesia MetaADEDB
Hypoaesthesia Facial MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypoglycaemic Encephalopathy MetaADEDB
Hypophagia MetaADEDB
Hypopharyngeal Cancer MetaADEDB
Hypotension Orthostatic MetaADEDB
Increased White Blood Cell Count MetaADEDB
Intra-Aortic Balloon Placement MetaADEDB
Light Sensitivity MetaADEDB
Lip Erosion MetaADEDB
Loss Of Control Of Legs MetaADEDB
Lymph Node Palpable MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocyte Stimulation Test Negative MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Macular Ischaemia MetaADEDB
Mechanical Ventilation MetaADEDB
Metabolic Acidosis MetaADEDB
Mouth Ulcer MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Drug Overdose MetaADEDB
Nephrogenic Anaemia MetaADEDB
Nephrotic Syndrome MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutrophil Count Decreased MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oliguria MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Klebsiella MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Wound Infection MetaADEDB
Procedural Pain MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time MetaADEDB
Pulmonary Arrest MetaADEDB
Renal Impairment MetaADEDB
Retinopathy Haemorrhagic MetaADEDB
Scab MetaADEDB
Shock Haemorrhagic MetaADEDB
Sick Sinus Syndrome MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Surgical Vascular Shunt MetaADEDB
Tachycardia Ventricular MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheostomy MetaADEDB
Transaminases Increased MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Urine Osmolarity Increased MetaADEDB
Vith Nerve Disorder MetaADEDB

InAADR: Drug-Protein-ADRs database