InAADR

Drug Information

Drug Name: diphenoxylate (915-30-0)
PubChem ID: 13505
SMILES: CCOC(=O)C1(CCN(CC1)CCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=CC=C4
InchiKey: HYPPXZBJBPSRLK-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Antidiarrheals, Central Nervous System Agents, Central Nervous System Depressants, Gastrointestinal Agents, Narcotics, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 452.598
LogP: 5.48328
Ring Count: 3
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 53.33

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Accelerated Hypertension MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acne MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adrenal Neoplasm MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Allergic Rhinitis MetaADEDB
Allergies MetaADEDB
Anaemia MetaADEDB
Angina Unstable MetaADEDB
Anhedonia MetaADEDB
Ankle Fracture MetaADEDB
Anorexia MetaADEDB
Anxiety MetaADEDB
Appendicitis Perforated MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Asthenia MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Beta Haemolytic Streptococcal Infection MetaADEDB
Bladder Retention MetaADEDB
Blood Cholesterol MetaADEDB
Blood Culture Positive MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Triglycerides Increased MetaADEDB
Bone Disorder MetaADEDB
Bone Erosion MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Fragmentation MetaADEDB
Bone Graft MetaADEDB
Bone Inflammation MetaADEDB
Bone Operation MetaADEDB
Bone Pain MetaADEDB
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Breast Calcifications MetaADEDB
Bruxism MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Catheter Site Haemorrhage MetaADEDB
Cellulitis MetaADEDB
Cerumen Impaction MetaADEDB
Choking Sensation MetaADEDB
Cholecystitis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Colitis MetaADEDB
Colon Spastic MetaADEDB
Compression Fracture MetaADEDB
Confabulation MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Constipated MetaADEDB
Crackles Lung MetaADEDB
Culture Positive MetaADEDB
Cystitis Bacterial MetaADEDB
Deafness MetaADEDB
Debridement MetaADEDB
Decreased Immune Responsiveness MetaADEDB
Decubitus Ulcer MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Caries MetaADEDB
Dental Pain MetaADEDB
Depressed Mood MetaADEDB
Dermatitis Exfoliative MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Neuropathy MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Dislocation MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Skin MetaADEDB
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Economic Problem MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Endodontic Procedure MetaADEDB
Enterococcal Infection MetaADEDB
Enterocutaneous Fistula MetaADEDB
Epidural Hematoma MetaADEDB
Erectile Dysfunction MetaADEDB
Eruption MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Excess Potassium MetaADEDB
Extremity Pain MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Febrile Neutropenia MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal MetaADEDB
Fibula Fracture MetaADEDB
Flatulence MetaADEDB
Fungal Disease MetaADEDB
Gangrene MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Sounds Abnormal MetaADEDB
Granulocytosis MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Head Injury MetaADEDB
Heart Attack MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatitis MetaADEDB
Hernia MetaADEDB
High Blood Pressure MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperlipaemia MetaADEDB
Hypoaesthesia MetaADEDB
Hypophosphataemia MetaADEDB
Hypoxia MetaADEDB
Immune System Disorder MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infection Urinary Tract MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Intentional Drug Misuse MetaADEDB
Intermittent Claudication MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Stenosis MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Jaw Fracture MetaADEDB
Jaw Operation MetaADEDB
Jugular Vein Distension MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leukopenia Neonatal MetaADEDB
Limb Discomfort MetaADEDB
Limb Injury MetaADEDB
Loss Of Weight MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lyell MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Occlusion MetaADEDB
Mucosal Erosion MetaADEDB
Multiple Injuries MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Nausea MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Nikolsky Sign MetaADEDB
No Therapeutic Response MetaADEDB
Oral Intake Reduced MetaADEDB
Oropharyngeal Pain MetaADEDB
Orthopnea MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Perirectal Abscess MetaADEDB
Pleural Effusion MetaADEDB
Pollakiuria MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Complication MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pseudomonas Infection MetaADEDB
Psoriasis MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Mass MetaADEDB
Purulence MetaADEDB
Rales MetaADEDB
Respiratory Failure MetaADEDB
Retinal Vascular Occlusion MetaADEDB
Rhinitis Seasonal MetaADEDB
Road Traffic Accident MetaADEDB
Scab MetaADEDB
Septic Shock MetaADEDB
Sequestrectomy MetaADEDB
Sinus Headache MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Social Avoidant Behaviour MetaADEDB
Speech Disorder MetaADEDB
Spinal Disorder MetaADEDB
Spondylolisthesis MetaADEDB
Stress MetaADEDB
Subcutaneous Abscess MetaADEDB
Tongue Eruption MetaADEDB
Tooth Extraction MetaADEDB
Unevaluable Event MetaADEDB
Urinary Tract Infection Staphylococcal MetaADEDB
Urosepsis MetaADEDB

InAADR: Drug-Protein-ADRs database