InAADR

Drug Information

Drug Name: Zopiclone (43200-80-2)
PubChem ID: 5735
SMILES: CN1CCN(CC1)C(=O)OC2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
InchiKey: GBBSUAFBMRNDJC-UHFFFAOYSA-N
Therapeutic Category: Central Nervous System Agents, Central Nervous System Depressants, Hypnotics and Sedatives

Computed Drug Properties

Molecular Weight (dalton): 388.815
LogP: 1.568
Ring Count: 2
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 91.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abscess Intestinal MetaADEDB
Acne ADReCS
Activities Of Daily Living Impaired MetaADEDB
Acute Abdomen MetaADEDB
Acute Graft Versus Host Disease In Liver MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Promyelocytic Leukaemia MetaADEDB
Adrenal Insufficiency MetaADEDB
Affect Lability ADReCS
Affective Disorder MetaADEDB
Agitation ADReCS
Aids Encephalopathy MetaADEDB
Alcohol Abuse MetaADEDB
Alcohol Intoxication SIDER
Alcohol Poisoning ADReCS
Alopecia ADReCS
Alopecia Universalis MetaADEDB
Altered State Of Consciousness ADReCS
Amblyopia ADReCS
Amenorrhoea ADReCS
Amnesia ADReCS
Amputation MetaADEDB
Anaemia ADReCS
Anal Erosion MetaADEDB
Anal Fissure MetaADEDB
Anaphylactic Shock ADReCS
Angioedema ADReCS
Anorexia ADReCS
Anterograde Amnesia ADReCS
Anxiety ADReCS
Aortic Regurgitation MetaADEDB
Apathy ADReCS
Appendix Disorder MetaADEDB
Application Site Discolouration MetaADEDB
Application Site Pruritus MetaADEDB
Application Site Rash MetaADEDB
Application Site Urticaria MetaADEDB
Arthritis ADReCS
Arthritis Rheumatoid MetaADEDB
Arthropathy ADReCS
Ascites MetaADEDB
Aspartate Aminotransferase Increased SIDER
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Attempted Suicide MetaADEDB
Aura MetaADEDB
Avoidant Personality Disorder MetaADEDB
B-Cell Lymphoma MetaADEDB
Back Pain ADReCS
Balance Disorder MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Adenoma MetaADEDB
Biopsy Breast Abnormal MetaADEDB
Bipolar Disorder MetaADEDB
Bipolar I Disorder MetaADEDB
Bladder Pain ADReCS
Blast Cells Present MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Body Temperature Increased ADReCS
Bone Debridement MetaADEDB
Bradypnoea MetaADEDB
Breast Cancer MetaADEDB
Breast Cancer Recurrent MetaADEDB
Breast Engorgement ADReCS
Breast Enlargement ADReCS
Breast Feeding ADReCS
Breast Neoplasm ADReCS
Breast Pain ADReCS
Breath Odour ADReCS
Bronchiectasis MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Bruxism MetaADEDB
Bunion MetaADEDB
Bursitis ADReCS
C-Reactive Protein Increased MetaADEDB
Calculus Of Kidney SIDER
Cardiac Discomfort MetaADEDB
Cardiac Disease MetaADEDB
Cardiopulmonary Failure MetaADEDB
Catatonia MetaADEDB
Cellulitis ADReCS
Central Nervous System Lymphoma MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Infarct MetaADEDB
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Chills ADReCS
Cholecystitis MetaADEDB
Cholelithiasis ADReCS
Chronic Fatigue Syndrome MetaADEDB
Coccydynia MetaADEDB
Colitis ADReCS
Colorectal Cancer Metastatic MetaADEDB
Compression Fracture MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Conjunctivitis ADReCS
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Coronary Artery Insufficiency MetaADEDB
Costochondritis MetaADEDB
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Culture Positive MetaADEDB
Cystitis ADReCS
Cystitis Noninfective ADReCS
Cytolytic Hepatitis ADReCS
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Delirium ADReCS
Demyelination MetaADEDB
Dependence MetaADEDB
Depressed Level Of Consciousness ADReCS
Depression Suicidal MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Contact ADReCS
Dermatitis Medicamentosa MetaADEDB
Device Dislocation MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disorder Retinal MetaADEDB
Disturbance In Attention MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Abuse ADReCS
Drug Addict MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Hypersensitivity ADReCS
Drug Intolerance ADReCS
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dysuria ADReCS
Ear Discomfort MetaADEDB
Ear Infection ADReCS
Ear Pain ADReCS
Early Morning Awakening MetaADEDB
Easy Bruisability MetaADEDB
Eczema ADReCS
Edema Extremities MetaADEDB
Elderly ADReCS
Electrocardiogram Qt Interval MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
Endocrine Neoplasm Malignant MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epistaxis ADReCS
Erosive Oesophagitis MetaADEDB
Erythema ADReCS
Erythema Annulare MetaADEDB
Erythema Multiforme ADReCS
Escherichia Infection MetaADEDB
Esophageal Stenosis MetaADEDB
Esophageal Ulcer MetaADEDB
Euphoric Mood ADReCS
Excessive Thirst MetaADEDB
Extrapyramidal Disorder MetaADEDB
Eyelid Ptosis ADReCS
Face Oedema ADReCS
Face Pain MetaADEDB
Facial Neuralgia MetaADEDB
Fat Tissue Increased MetaADEDB
Fatty Liver MetaADEDB
Feeling Abnormal ADReCS
Femur Fracture MetaADEDB
Finger Amputation MetaADEDB
Flat Affect ADReCS
Furuncle ADReCS
Furunculosis SIDER
Gait Disturbance ADReCS
Gambling MetaADEDB
Gastric Disorder ADReCS
Gastric Ulcer ADReCS
Gastric Ulcer Perforated MetaADEDB
Gastritis ADReCS
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Generalised Anxiety Disorder MetaADEDB
Gingival Pain MetaADEDB
Glucose Intolerance MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Gout ADReCS
Gynaecomastia ADReCS
Haematemesis MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Hair Growth Abnormal MetaADEDB
Hairy Cell Leukaemia MetaADEDB
Hallucination ADReCS
Head Injury MetaADEDB
Headache ADReCS
Heaviness In Limbs SIDER
Hepatic Enzyme MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis Fulminant MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury ADReCS
Hepatomegaly ADReCS
Hepatosplenomegaly MetaADEDB
Hernia ADReCS
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hiccough MetaADEDB
Hiccups ADReCS
Hip Arthroplasty MetaADEDB
Hirsutism ADReCS
Homicidal Ideation MetaADEDB
Hostility ADReCS
Hot Flash MetaADEDB
Humerus Fracture MetaADEDB
Hyperacusis ADReCS
Hyperaemia ADReCS
Hyperaesthesia ADReCS
Hyperalimentation MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hyperkeratosis MetaADEDB
Hyperlipaemia MetaADEDB
Hyperlipidaemia ADReCS
Hypersensitivity ADReCS
Hypersexuality MetaADEDB
Hypertension ADReCS
Hypertonia ADReCS
Hypertonic Bladder MetaADEDB
Hypertrophy ADReCS
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hyporeflexia ADReCS
Hypotonia ADReCS
Ichthyosis MetaADEDB
Ill-Defined Disorder ADReCS
Impaired Healing MetaADEDB
Impulse-Control Disorder MetaADEDB
Incontinence ADReCS
Increased Appetite ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Influenza ADReCS
Intentional Misuse MetaADEDB
Intercostal Neuralgia MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intestinal Perforation MetaADEDB
Iritis ADReCS
Irritability ADReCS
Laboratory Test Abnormal ADReCS
Large Intestine Perforation MetaADEDB
Laryngitis ADReCS
Left Ventricular Hypertrophy MetaADEDB
Leg Cramps ADReCS
Lethargy MetaADEDB
Leukopenia Neonatal MetaADEDB
Libido Decreased ADReCS
Lightheadedness SIDER
Lip Pain MetaADEDB
Liver Injury ADReCS
Liver Palpable Subcostal MetaADEDB
Liver Transplant Rejection MetaADEDB
Localised Oedema MetaADEDB
Logorrhoea MetaADEDB
Lung Infiltration MetaADEDB
Lung Squamous Cell Carcinoma Recurrent MetaADEDB
Lymphadenopathy ADReCS
Major Depression MetaADEDB
Malaise ADReCS
Mastitis ADReCS
Melaena ADReCS
Memory Impairment ADReCS
Menorrhagia ADReCS
Mental Disability ADReCS
Mental Disorder MetaADEDB
Metastases To Meninges MetaADEDB
Metrorrhagia ADReCS
Migraine ADReCS
Miosis MetaADEDB
Mononeuropathy MetaADEDB
Mood Disorder Due To A General Medical Condition MetaADEDB
Mood Swings ADReCS
Motor Retardation MetaADEDB
Mouth Ulceration ADReCS
Muscle Inflammation MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscle Strain MetaADEDB
Muscle Twitching ADReCS
Muscle Weakness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myasthenia SIDER
Mydriasis ADReCS
Myopathy ADReCS
Nausea ADReCS
Neck Stiffness ADReCS
Neoplasm ADReCS
Nephrolithiasis ADReCS
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neuralgia ADReCS
Neuritis ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neurosis ADReCS
Nightmare ADReCS
Nuchal Rigidity ADReCS
Nystagmus ADReCS
Obsessive-Compulsive Personality Disorder MetaADEDB
Oculogyric Crisis MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophagitis Ulcerative MetaADEDB
Oliguria ADReCS
Onychomadesis MetaADEDB
Oral Mucosa Erosion MetaADEDB
Osteoarthritis ADReCS
Osteochondrosis MetaADEDB
Otitis SIDER
Otitis Externa ADReCS
Otitis Media ADReCS
Pain ADReCS
Palmar Erythema MetaADEDB
Palpitations ADReCS
Panic Disorder MetaADEDB
Paraesthesia ADReCS
Penile Pain MetaADEDB
Pharyngitis ADReCS
Photophobia ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pneumococcal Sepsis MetaADEDB
Pollakiuria ADReCS
Polysubstance Dependence MetaADEDB
Polyuria MetaADEDB
Poor Dental Condition MetaADEDB
Postmenopausal Bleeding MetaADEDB
Postoperative Wound Infection MetaADEDB
Posture Abnormal MetaADEDB
Precancerous Cells Present MetaADEDB
Procedural Pain MetaADEDB
Prostatic Disorder MetaADEDB
Protein Total Decreased MetaADEDB
Pruritus ADReCS
Pseudoaldosteronism MetaADEDB
Pseudomonas Infection MetaADEDB
Psoriatic Arthritis MetaADEDB
Ptosis SIDER
Pyelonephritis ADReCS
Radiculitis Brachial MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Rash Pustular ADReCS
Rectal Haemorrhage ADReCS
Renal Cyst MetaADEDB
Renal Pain ADReCS
Retinal Bleeding MetaADEDB
Rhinitis ADReCS
Salivary Hypersecretion ADReCS
Seizures SIDER
Self Injurious Behaviour MetaADEDB
Sensation Of Foreign Body MetaADEDB
Sensation Of Heaviness ADReCS
Sensory Loss MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sjogren Syndrome MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration ADReCS
Sleep Apnea MetaADEDB
Sleep Disorder MetaADEDB
Sleep Terror MetaADEDB
Sleepy SIDER
Somatoform Disorder MetaADEDB
Somnolence ADReCS
Speech Disorder ADReCS
Sphincter Of Oddi Dysfunction MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Fracture MetaADEDB
Spontaneous Haematoma MetaADEDB
Sputum Retention MetaADEDB
Staring MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stiffness SIDER
Stomatitis ADReCS
Stupor ADReCS
Sudden Death MetaADEDB
Suicidal Behaviour MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Suprapubic Pain MetaADEDB
Surgery MetaADEDB
Sweating SIDER
Swelling ADReCS
Swollen Tongue ADReCS
Tachycardia ADReCS
Taste Bitter ADReCS
Tension ADReCS
Thalassaemia MetaADEDB
Therapeutic Response Decreased MetaADEDB
Thinking Abnormal ADReCS
Thirst ADReCS
Thoracic Vertebral Fracture MetaADEDB
Thrombophlebitis ADReCS
Thyroid Function Test MetaADEDB
Tinnitus ADReCS
Tongue Coated ADReCS
Tongue Disorder ADReCS
Tongue Oedema ADReCS
Tooth Infection MetaADEDB
Toxic Encephalopathy MetaADEDB
Tremor ADReCS
Ulcer ADReCS
Ulcerative Stomatitis SIDER
Unresponsive To Pain Stimuli MetaADEDB
Urethritis ADReCS
Urinary Incontinence ADReCS
Urinary Tract Infection ADReCS
Urticaria ADReCS
Uterine Haemorrhage ADReCS
Uterovaginal Prolapse ADReCS
Vaginal Haemorrhage ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vena Cava Filter Insertion MetaADEDB
Venous Thrombosis Limb MetaADEDB
Vertigo ADReCS
Vesiculobullous Rash SIDER
Vestibular Disorder ADReCS
Viral Infection ADReCS
Vomiting ADReCS
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Wheeze MetaADEDB
White Blood Cell Count Abnormal MetaADEDB
White Blood Cell Disorder MetaADEDB
Withdrawal Syndrome ADReCS

InAADR: Drug-Protein-ADRs database