InAADR

Drug Information

Drug Name: Trospium (10405-02-4)
PubChem ID: 24804376
SMILES: C1CC[N+]2(C1)[C@@H]3CC[C@@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O.[Cl-]
InchiKey: RVCSYOQWLPPAOA-HLUKFBSCSA-M
Therapeutic Category: Analgesics, Autonomic Agents, Central Nervous System Agents, Cholinergic Agents, Cholinergic Antagonists, Muscarinic Antagonists, Neurotransmitter Agents, Parasympatholytics, Peripheral Nervous System Agents, Sensory System Agents, Urological Agents

Computed Drug Properties

Molecular Weight (dalton): 427.972
LogP: 0.7737
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Hernia MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Strangulated Hernia MetaADEDB
Abnormal Vision MetaADEDB
Abscess Limb MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accommodation Disorder ADReCS
Acquired Oesophageal Web MetaADEDB
Acquired Porphyria MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Abdomen MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Prerenal Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adrenal Neoplasm MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agraphia MetaADEDB
Alveolitis MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anemia Aplastic MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anhedonia MetaADEDB
Anuria MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aortic Stenosis MetaADEDB
Apoplexy MetaADEDB
Application Site Rash MetaADEDB
Application Site Ulcer MetaADEDB
Aptyalism MetaADEDB
Arrhythmia MetaADEDB
Arterial Disorder ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis Infective MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspergillosis MetaADEDB
Asphyxia MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Atrial Tachycardia MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Automatism MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Balance Disorder MetaADEDB
Bilateral Hydronephrosis MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Pain ADReCS
Bladder Retention MetaADEDB
Bleb MetaADEDB
Blepharitis MetaADEDB
Blindness ADReCS
Blood Albumin Decreased MetaADEDB
Blood Calcium MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood In Urine MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid Increased ADReCS
Blurred Vision MetaADEDB
Body Temperature Fluctuation MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Fragmentation MetaADEDB
Bone Operation MetaADEDB
Bradypnoea MetaADEDB
Breast Cancer Recurrent MetaADEDB
Breast Discharge MetaADEDB
Breast Disorder SIDER
Bronchoalveolar Lavage MetaADEDB
Bruise MetaADEDB
Bulbar Palsy MetaADEDB
Burn Oesophageal MetaADEDB
Caecitis MetaADEDB
Candida Infection MetaADEDB
Cardiac Ablation MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disorder ADReCS
Cardiogenic Shock MetaADEDB
Cartilage Development Disorder MetaADEDB
Cataract Operation MetaADEDB
Catatonia MetaADEDB
Catheter Site Pain MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Lymphoma MetaADEDB
Central Venous Catheter Removal MetaADEDB
Cervical Cord Compression MetaADEDB
Cervical Dysplasia MetaADEDB
Cervical Laser Therapy MetaADEDB
Cervical Myelopathy MetaADEDB
Cervical Spinal Stenosis MetaADEDB
Cervicitis MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Cholangitis Chronic MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis Acute MetaADEDB
Cholecystitis Infective MetaADEDB
Colitis MetaADEDB
Colon Neoplasm MetaADEDB
Colon Spastic MetaADEDB
Colonic Obstruction MetaADEDB
Compression Fracture MetaADEDB
Condition Aggravated ADReCS
Connective Tissue Disorder SIDER
Constipated MetaADEDB
Constipation ADReCS
Coronary Artery Disease ADReCS
Costochondritis MetaADEDB
Cough MetaADEDB
Cramp Muscle SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Csf Protein MetaADEDB
Cystitis Noninfective MetaADEDB
Deafness Congenital MetaADEDB
Debridement MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Deglutition Disorder MetaADEDB
Delirium ADReCS
Demyelination MetaADEDB
Dental Caries MetaADEDB
Dental Pain MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Dermatitis Contact ADReCS
Device Breakage MetaADEDB
Device Related Infection MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Discomfort ADReCS
Disorder Renal MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drug Ineffective MetaADEDB
Drug Interaction MetaADEDB
Drug Intolerance MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dry Throat ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dysphonia ADReCS
Dysuria ADReCS
Ear Pain ADReCS
Eczema ADReCS
Edentulous MetaADEDB
Electrocardiogram Abnormal SIDER
Electrolyte Disorder MetaADEDB
Elevated Prostate Specific Antigen MetaADEDB
Embolism Pulmonary MetaADEDB
Encephalitis Post Measles MetaADEDB
Endocrine Disorder SIDER
Endodontic Procedure MetaADEDB
Endometriosis MetaADEDB
Enlarged Spleen MetaADEDB
Enteritis Necroticans MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction MetaADEDB
Erosive Gastritis MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
Erythropoiesis Abnormal MetaADEDB
Eschar MetaADEDB
Escherichia Infection MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles ADReCS
Eye Disorder SIDER
Eye Infection Viral MetaADEDB
Eye Pain ADReCS
Facial Bones Fracture MetaADEDB
Faecaloma MetaADEDB
Faeces Hard ADReCS
Fatigue ADReCS
Fatty Stools MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Femoral Neck Fracture MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Food Aversion MetaADEDB
Formication MetaADEDB
Fractured Coccyx MetaADEDB
Fungaemia MetaADEDB
Fungal Disease MetaADEDB
Fungal Sepsis MetaADEDB
Gangrene MetaADEDB
Gastric Disorder MetaADEDB
Gastritis ADReCS
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Infection MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Toxicity MetaADEDB
Gingival Infection MetaADEDB
Gingival Pain MetaADEDB
Granulomatous Liver Disease MetaADEDB
Haematemesis MetaADEDB
Haematochezia MetaADEDB
Haematuria ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhoid Operation MetaADEDB
Hair Growth Abnormal ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Attack MetaADEDB
Heart Injury MetaADEDB
Heart Rate Increased MetaADEDB
Heat Stroke MetaADEDB
Hemiparesis MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Lesion MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hernia Hiatal MetaADEDB
Hernia Inguinal MetaADEDB
Hernia Obstructive MetaADEDB
Herpes Zoster Disseminated MetaADEDB
Hesitancy MetaADEDB
Hiccough MetaADEDB
Hoarseness SIDER
Hormone Level Abnormal SIDER
Hot Flush ADReCS
Hydroureter MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperhidrosis ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hypertensive Crisis ADReCS
Hyperuricaemia ADReCS
Hyperventilation MetaADEDB
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypovolaemia MetaADEDB
Ill-Defined Disorder ADReCS
Immune Reconstitution Syndrome MetaADEDB
Immunosuppression MetaADEDB
Impaired Healing MetaADEDB
Impaired Work Ability MetaADEDB
Incisional Drainage MetaADEDB
Incontinence MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Influenza Like Illness ADReCS
Inguinal Hernia Repair MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Pruritus MetaADEDB
Injection Site Warmth MetaADEDB
Intention Tremor MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Prolapse MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Intravascular Haemolysis MetaADEDB
Iron Metabolism Disorder MetaADEDB
Joint Injection MetaADEDB
Joint Prosthesis User MetaADEDB
Kidney Failure MetaADEDB
Kidney Transplant Rejection MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Laryngeal Inflammation MetaADEDB
Light Sensitivity MetaADEDB
Lipoma Excision MetaADEDB
Localised Infection MetaADEDB
Loss Of Consciousness ADReCS
Lumbar Spinal Stenosis MetaADEDB
Lung Adenocarcinoma MetaADEDB
Lung Cancer Metastatic MetaADEDB
Lung Edema MetaADEDB
Lymphadenopathy ADReCS
Lymphocele MetaADEDB
Malabsorption MetaADEDB
Malaise ADReCS
Malnourished MetaADEDB
Mastication Disorder MetaADEDB
Mediastinal Disorder SIDER
Meningioma MetaADEDB
Menopausal Symptoms ADReCS
Micturition Disorder ADReCS
Micturition Urgency ADReCS
Migraine ADReCS
Mouth Ulceration ADReCS
Multifocal Leukoencephalopathy MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Spasms ADReCS
Myotonia MetaADEDB
Nail Disorder MetaADEDB
Nasal Congestion MetaADEDB
Nasal Dryness ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neurogenic Bowel MetaADEDB
Nocturia MetaADEDB
Nodule MetaADEDB
Nonspecific Reaction MetaADEDB
Nosocomial Infection MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Oedema ADReCS
Oedema Mouth MetaADEDB
Oedema Peripheral ADReCS
Oesophageal Candidiasis MetaADEDB
Oesophageal Obstruction MetaADEDB
Off Label Use MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Pain ADReCS
Pain In Jaw ADReCS
Pain In Throat MetaADEDB
Pallor MetaADEDB
Palpitations ADReCS
Pancreatic Insufficiency MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Periodontal Disease MetaADEDB
Periodontitis MetaADEDB
Peyronie Disease MetaADEDB
Pharyngeal Inflammation MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Plasmacytoma MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pleurisy MetaADEDB
Pneumatosis MetaADEDB
Pollakiuria ADReCS
Polyuria MetaADEDB
Poor Quality Sleep MetaADEDB
Post Polio Syndrome MetaADEDB
Post Procedural Complication MetaADEDB
Posterior Capsule Opacification MetaADEDB
Posterior Capsulotomy MetaADEDB
Postoperative Wound Complication MetaADEDB
Prostatic Obstruction MetaADEDB
Pruritus ADReCS
Pulpitis Dental MetaADEDB
Pyelonephritis MetaADEDB
Rash ADReCS
Rash Erythematous ADReCS
Reflux Esophagitis MetaADEDB
Renal Cyst MetaADEDB
Renal Pain ADReCS
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Sacroiliitis MetaADEDB
Scar MetaADEDB
Sclc MetaADEDB
Scoliosis MetaADEDB
Sensation Of Heaviness MetaADEDB
Septic Shock MetaADEDB
Seroma MetaADEDB
Shock ADReCS
Shoulder Operation MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sickness SIDER
Skin Laceration MetaADEDB
Skin Lesion MetaADEDB
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Spinal Compression Fracture MetaADEDB
Spinal Osteoarthritis MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stomatitis ADReCS
Streptococcal Bacteraemia MetaADEDB
Stress MetaADEDB
Stress Incontinence MetaADEDB
Supraventricular Extrasystoles ADReCS
Supraventricular Tachyarrhythmia ADReCS
Supraventricular Tachycardia ADReCS
Sweating SIDER
Sweating Increased SIDER
Swelling ADReCS
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Temperature Intolerance MetaADEDB
Therapeutic Response Unexpected With Drug Substitution MetaADEDB
Thirst ADReCS
Tinnitus MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Loss MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheobronchitis MetaADEDB
Ulcer ADReCS
Umbilical Hernia MetaADEDB
Umbilical Hernia Repair MetaADEDB
Unevaluable Event MetaADEDB
Ureterostomy Site Discomfort MetaADEDB
Urethral Disorder SIDER
Urinary Hesitation ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urinary Tract Obstruction ADReCS
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urine Odour Abnormal ADReCS
Urine Output ADReCS
Urosepsis MetaADEDB
Urticaria ADReCS
Vaginal Pain SIDER
Vascular Rupture MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertebroplasty MetaADEDB
Vision Abnormal ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vitamin A Deficiency MetaADEDB
Vocal Cord Disorder MetaADEDB
Vomiting ADReCS
Vulvovaginal Pain ADReCS
Weight Bearing Difficulty MetaADEDB
Weight Gain MetaADEDB
Weight Increased ADReCS
Wound Dehiscence MetaADEDB

InAADR: Drug-Protein-ADRs database