InAADR

Drug Information

Drug Name: Toremifene (89778-26-7)
PubChem ID: 6536897
SMILES: CN(C)CCOC1=CC=C(C=C1)/C(=C(CCCl)/C2=CC=CC=C2)/C3=CC=CC=C3
InchiKey: XFCLJVABOIYOMF-OCEACIFDSA-N
Therapeutic Category: Antineoplastic Agents, Bone Density Conservation Agents, Estrogen Receptor Modulators, Hormone Antagonists, Hormones, Selective Estrogen Receptor Modulators

Computed Drug Properties

Molecular Weight (dalton): 405.969
LogP: 6.215
Ring Count: 3
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 12.47

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Vision ADReCS
Abscess MetaADEDB
Abscess Jaw MetaADEDB
Abscess Oral MetaADEDB
Accident MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Leukaemia MetaADEDB
Adenocarcinoma MetaADEDB
Adrenal Neoplasm MetaADEDB
Alopecia ADReCS
Anaemia MetaADEDB
Angina Pectoris ADReCS
Anorexia ADReCS
Aortic Calcification MetaADEDB
Appendectomy MetaADEDB
Arrhythmia ADReCS
Arthritis ADReCS
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Atrophy MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Back Ache MetaADEDB
Basal Cell Carcinoma MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Inflammation MetaADEDB
Blast Cell Count Decreased MetaADEDB
Bleb MetaADEDB
Bleeding Gums MetaADEDB
Bleeding Vaginal SIDER
Blindness ADReCS
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Bilirubin Increased ADReCS
Blood Creatinine Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blurred Vision MetaADEDB
Body Height Decreased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Trimming MetaADEDB
Brain Oedema MetaADEDB
Breast Cellulitis MetaADEDB
Breast Neoplasms MetaADEDB
Bursitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Carcinoma Renal Cell MetaADEDB
Cardiac Failure ADReCS
Carotid Artery Stenosis MetaADEDB
Cataract ADReCS
Cell Marker Increased MetaADEDB
Cerebrovascular Accident ADReCS
Cheilitis MetaADEDB
Chills ADReCS
Clavicle Fracture MetaADEDB
Colonic Polyp MetaADEDB
Computerised Tomogram MetaADEDB
Condition Aggravated MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipation ADReCS
Coordination Abnormal ADReCS
Corneal Infection MetaADEDB
Corneal Opacity ADReCS
Cough MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Debridement MetaADEDB
Decreased Appetite ADReCS
Deep Vein Thrombosis PROTECT
Deglutition Disorder MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dilatation Ventricular MetaADEDB
Diplopia ADReCS
Disease Of Liver MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dry Eye ADReCS
Dysgeusia MetaADEDB
Dyspnoea ADReCS
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Electrocardiogram Qt Prolonged PROTECT
Embolism ADReCS
Embolism Arterial PROTECT
Enamel Anomaly MetaADEDB
Endometrial Cancer PROTECT
Endometrial Cancer Stage Iii MetaADEDB
Endometrial Hyperplasia PROTECT
Endometrial Hypertrophy PROTECT
Erosive Gastritis MetaADEDB
Ethmoid Sinus Surgery MetaADEDB
Excessive Granulation Tissue MetaADEDB
Eyelid Operation MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Female Urogenital Diseases MetaADEDB
Fibroids MetaADEDB
Fibromyalgia MetaADEDB
Fistula MetaADEDB
Flank Pain MetaADEDB
Floaters MetaADEDB
Fractured Pelvis Nos MetaADEDB
Gamma-Glutamyltransferase MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gingival Blister MetaADEDB
Gingival Disorder MetaADEDB
Glaucoma ADReCS
Glycosylated Haemoglobin Increased MetaADEDB
Goiter MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhagic Hepatic Cyst MetaADEDB
Headache PROTECT
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatocellular Damage MetaADEDB
Hepatotoxicity ADReCS
Hordeolum MetaADEDB
Hot Flush ADReCS
Hydronephrosis MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercalcaemia ADReCS
Hyperhidrosis ADReCS
Hyperphosphatasaemia MetaADEDB
Hypothyroid MetaADEDB
Ild MetaADEDB
Impaired Healing MetaADEDB
Impingement Syndrome MetaADEDB
Infarction ADReCS
Insomnia PROTECT
Intervertebral Disc Degeneration MetaADEDB
Jaundice ADReCS
Jaw Lesion Excision MetaADEDB
Keratopathy ADReCS
Lactose Intolerance MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Lethargy ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Liver Function Test Abnormal ADReCS
Liver Neoplasms MetaADEDB
Lymphedema MetaADEDB
Malignant Melanoma In Situ MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Maxillofacial Operation MetaADEDB
Menopausal Symptoms ADReCS
Metastases To Liver MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Mouth Pain MetaADEDB
Muscle Necrosis MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Myelopathy MetaADEDB
Myocardial Infarction ADReCS
Nasal Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrotic Syndrome MetaADEDB
Nocturia MetaADEDB
Non-Alcoholic Fatty Liver Disease MetaADEDB
Oedema ADReCS
Oral Cavity Fistula MetaADEDB
Oral Discomfort MetaADEDB
Oral Disorder MetaADEDB
Oral Soft Tissue Disorder MetaADEDB
Oroantral Fistula MetaADEDB
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Ovarian Cancer MetaADEDB
Ovarian Granulosa-Theca Cell Tumour MetaADEDB
Paraesthesia Oral MetaADEDB
Paresis ADReCS
Patellofemoral Pain Syndrome MetaADEDB
Periodontal Disease MetaADEDB
Peripheral Artery Aneurysm MetaADEDB
Peritoneal Dialysis MetaADEDB
Pituitary Neoplasms MetaADEDB
Poor Quality Sleep MetaADEDB
Post Nasal Drip MetaADEDB
Precancerous Conditions MetaADEDB
Primary Sequestrum MetaADEDB
Pruritus ADReCS
Pulmonary Embolism ADReCS
Pulmonary Thrombosis MetaADEDB
Purulence MetaADEDB
Purulent Discharge MetaADEDB
Pyogenic Granuloma MetaADEDB
Rash PROTECT
Renal Atrophy MetaADEDB
Renal Cyst MetaADEDB
Retinal Disorder ADReCS
Rhinorrhea MetaADEDB
Rigors SIDER
Sacroiliitis MetaADEDB
Sarcoma Uterus MetaADEDB
Sclerema MetaADEDB
Secondary Sequestrum MetaADEDB
Sensitivity Of Teeth MetaADEDB
Sequestrectomy MetaADEDB
Sinus Antrostomy MetaADEDB
Sinus Disorder MetaADEDB
Sinus Operation MetaADEDB
Sinus Polyp MetaADEDB
Sinusitis MetaADEDB
Skin Discolouration ADReCS
Skin Neoplasm Excision MetaADEDB
Social Avoidant Behaviour ADReCS
Spermatocele MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Disorder MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Suture Rupture MetaADEDB
Sweating SIDER
Testicular Neoplasms MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Thrombosis ADReCS
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Infection MetaADEDB
Torsade De Pointes MetaADEDB
Transaminases Increased PROTECT
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Upper Limb Fracture MetaADEDB
Urge Incontinence MetaADEDB
Uterine Cancer MetaADEDB
Uterine Enlargement MetaADEDB
Uterine Haemorrhage PROTECT
Uterine Polyp PROTECT
Vaginal Discharge ADReCS
Vaginal Haemorrhage ADReCS
Venous Thrombosis MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Field Tests Abnormal ADReCS
Visual Impairment ADReCS
Vitreous Detachment MetaADEDB
Vomiting ADReCS
Weight Increased PROTECT
Withdrawn SIDER
Wound Debridement MetaADEDB

InAADR: Drug-Protein-ADRs database