InAADR

Drug Information

Drug Name: Tolvaptan (150683-30-0)
PubChem ID: 216237
SMILES: CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
InchiKey: GYHCTFXIZSNGJT-UHFFFAOYSA-N
Therapeutic Category: Antidiuretic Hormone Receptor Antagonists, Natriuretic Agents

Computed Drug Properties

Molecular Weight (dalton): 448.95
LogP: 5.68314
Ring Count: 3
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 69.64

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Angiopathy ADReCS
Anorexia ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Asthenia ADReCS
Blood Creatinine Increased PROTECT
Blood Urine Present PROTECT
Body Temperature Increased ADReCS
Breast Disorder SIDER
Cardiac Disorder ADReCS
Cardiac Fibrillation ADReCS
Cerebrovascular Accident ADReCS
Clot Blood SIDER
Colitis ADReCS
Colitis Ischaemic ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Death ADReCS
Decreased Appetite ADReCS
Deep Vein Thrombosis ADReCS
Dehydration PROTECT
Diabetes Mellitus ADReCS
Diabetic Ketoacidosis ADReCS
Diarrhoea PROTECT
Disseminated Intravascular Coagulation ADReCS
Dizziness PROTECT
Dry Mouth ADReCS
Dysgeusia PROTECT
Ecchymosis PROTECT
Embolism ADReCS
Gastrointestinal Disorder SIDER
Haemoglobin ADReCS
Haemorrhage ADReCS
Headache PROTECT
Hyperglycaemia ADReCS
Hyperkalaemia PROTECT
Hypernatraemia PROTECT
Hyperuricaemia PROTECT
Hypoglycaemia PROTECT
Hyponatraemia ADReCS
Hyponatraemic SIDER
Intracardiac Thrombus ADReCS
Ketoacidosis ADReCS
Malaise PROTECT
Mediastinal Disorder SIDER
Micturition Urgency ADReCS
Nausea ADReCS
Nocturia ADReCS
Orthostatic Hypotension PROTECT
Pollakiuria ADReCS
Polydipsia ADReCS
Polyuria ADReCS
Prothrombin Level Increased ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus PROTECT
Pulmonary Embolism ADReCS
Pyrexia ADReCS
Rapid Correction Of Hyponatraemia PROTECT
Rash Pruritic PROTECT
Renal Impairment PROTECT
Respiratory Failure ADReCS
Rhabdomyolysis ADReCS
Syncope PROTECT
Thirst ADReCS
Thrombosis ADReCS
Urethral Disorder SIDER
Urethral Haemorrhage ADReCS
Urinary Tract Disorder SIDER
Urine Output ADReCS
Urine Output Increased ADReCS
Vaginal Haemorrhage ADReCS
Venous Thrombosis ADReCS
Ventricular Fibrillation ADReCS

InAADR: Drug-Protein-ADRs database