InAADR

Drug Information

Drug Name: Tolazamide (1156-19-0)
PubChem ID: 5503
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2
InchiKey: OUDSBRTVNLOZBN-UHFFFAOYSA-N
Therapeutic Category: Hypoglycemic Agents

Computed Drug Properties

Molecular Weight (dalton): 311.407
LogP: 1.77392
Ring Count: 1
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 78.51

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Tolazamide-Induced Wernicke Encephalopathy Transketolase (P29401) Transketolase abnormality in tolazamide-induced Wernicke#s encephalopathy [ ADR Type 3 ] Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abnormal Faeces ADReCS
Abnormal Gait ADReCS
Accidental Injury ADReCS
Adrenal Insufficiency ADReCS
Adverse Event ADReCS
Affect Lability ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Alcohol Intolerance ADReCS
Allergic Reaction ADReCS
Alopecia ADReCS
Amblyopia ADReCS
Amnesia ADReCS
Anaemia ADReCS
Angina Pectoris ADReCS
Anorexia ADReCS
Anxiety ADReCS
Apathy ADReCS
Aphasia ADReCS
Aplastic Anaemia ADReCS
Apnoea ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Ascites ADReCS
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Atelectasis ADReCS
Atrial Fibrillation ADReCS
Back Pain ADReCS
Biliary Colic ADReCS
Blood Creatinine Increased ADReCS
Body Fat Disorder ADReCS
Bone Pain ADReCS
Bradycardia ADReCS
Bronchitis ADReCS
Cachexia ADReCS
Cardiac Failure Congestive ADReCS
Cardiomegaly ADReCS
Cellulitis ADReCS
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Chills ADReCS
Cholangitis ADReCS
Cholecystitis ADReCS
Chronic Obstructive Pulmonary Disease ADReCS
Colitis ADReCS
Confusional State ADReCS
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Cough ADReCS
Cough Increased ADReCS
Cyanosis ADReCS
Deep Vein Thrombosis ADReCS
Dehydration ADReCS
Delirium ADReCS
Dementia ADReCS
Dependence ADReCS
Depersonalisation ADReCS
Depression ADReCS
Dermatitis ADReCS
Diabetes Mellitus ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Diverticulitis ADReCS
Dizziness ADReCS
Drug Dependence ADReCS
Drug Hypersensitivity ADReCS
Drug-Induced Liver Injury MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dysgeusia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphoria ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Ecchymosis ADReCS
Electrocardiogram Abnormal ADReCS
Electrocardiogram Qt Prolonged ADReCS
Embolism Arterial ADReCS
End Stage Liver Disease MetaADEDB
Enterocolitis ADReCS
Epigastric Fullness SIDER
Epistaxis ADReCS
Eructation ADReCS
Eruption SIDER
Erythema ADReCS
Face Oedema ADReCS
Faecal Incontinence ADReCS
Faecaloma ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Flank Pain ADReCS
Flatulence ADReCS
Gastrointestinal Disorder ADReCS
Gastrointestinal Disturbance ADReCS
Gastrointestinal Haemorrhage ADReCS
Generalised Oedema ADReCS
Glossitis ADReCS
Gout ADReCS
Haematuria ADReCS
Haemolytic Anaemia ADReCS
Haemoptysis ADReCS
Haemorrhage ADReCS
Hallucination ADReCS
Headache ADReCS
Heartburn ADReCS
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Steatosis ADReCS
Hepatomegaly ADReCS
Herpes Simplex ADReCS
Herpes Zoster ADReCS
Hiccups ADReCS
Hostility ADReCS
Hyperacusis ADReCS
Hypercalcaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkinesia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia ADReCS
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hyponatraemia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Hypotonia ADReCS
Hypoventilation ADReCS
Hypoxia ADReCS
Ileus ADReCS
Ill-Defined Disorder ADReCS
Impotence ADReCS
Inappropriate Antidiuretic Hormone Secretion ADReCS
Increased Appetite ADReCS
Infection ADReCS
Influenza ADReCS
Infusion Related Reaction ADReCS
Insomnia ADReCS
Intestinal Obstruction ADReCS
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaundice Obstructive MetaADEDB
Lacrimal Disorder ADReCS
Lactic Acidosis ADReCS
Laryngospasm ADReCS
Leg Cramps ADReCS
Leukocytosis ADReCS
Leukopenia ADReCS
Liver Function Test Abnormal ADReCS
Lung Disorder ADReCS
Lung Neoplasm Malignant ADReCS
Lymphadenopathy ADReCS
Malaise ADReCS
Melaena ADReCS
Micturition Urgency ADReCS
Migraine ADReCS
Mouth Ulceration ADReCS
Muscle Twitching ADReCS
Muscular Weakness ADReCS
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Pain ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Nephrosis MetaADEDB
Nervousness ADReCS
Neuralgia ADReCS
Nystagmus ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophagitis ADReCS
Orthostatic Hypotension ADReCS
Overdose ADReCS
Pain ADReCS
Pain In Extremity ADReCS
Pallor ADReCS
Palpitations ADReCS
Pancytopenia ADReCS
Paraesthesia ADReCS
Paraesthesia Oral ADReCS
Paranoia ADReCS
Petechiae ADReCS
Pharyngitis ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Pollakiuria ADReCS
Porphyria ADReCS
Porphyria Cutanea Tarda SIDER
Porphyria Hepatic SIDER
Porphyria Non-Acute ADReCS
Pruritus ADReCS
Pseudolymphoma ADReCS
Pyelonephritis Acute ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Maculo-Papular ADReCS
Rash Morbilliform ADReCS
Reaction Gastrointestinal SIDER
Rectal Haemorrhage ADReCS
Renal Disorder ADReCS
Respiratory Acidosis ADReCS
Respiratory Tract Infection Viral ADReCS
Rhinitis ADReCS
Rhonchi ADReCS
Salivary Hypersecretion ADReCS
Sedation ADReCS
Sepsis ADReCS
Sinusitis ADReCS
Sleep Disorder ADReCS
Somnolence ADReCS
Speech Disorder ADReCS
Stevens-Johnson Syndrome ADReCS
Stupor ADReCS
Supraventricular Tachycardia ADReCS
Syncope ADReCS
Tachycardia ADReCS
Thinking Abnormal ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Thrombosis ADReCS
Tinnitus ADReCS
Tongue Oedema ADReCS
Toxic Epidermal Necrolysis ADReCS
Tremor ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urticaria ADReCS
Vasodilatation ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Wernicke Encephalopathy MetaADEDB
Withdrawal Syndrome ADReCS

InAADR: Drug-Protein-ADRs database