InAADR

Drug Information

Drug Name: Ticagrelor (274693-27-5)
PubChem ID: 9871419
SMILES: CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO
InchiKey: OEKWJQXRCDYSHL-FNOIDJSQSA-N
Therapeutic Category: Neurotransmitter Agents, Purinergic Agents, Purinergic Antagonists, Purinergic P2 Receptor Antagonists, Purinergic P2Y Receptor Antagonists

Computed Drug Properties

Molecular Weight (dalton): 522.578
LogP: 2.0137
Ring Count: 3
Hydrogen Bond Acceptor Count: 11
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 138.44

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Gastrointestinal Bleeding Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain PROTECT
Angioedema PROTECT
Atrial Fibrillation ADReCS
Back Pain ADReCS
Blood Creatinine Increased ADReCS
Blood Uric Acid Increased ADReCS
Blood Urine Present PROTECT
Bradyarrhythmia ADReCS
Bradycardia ADReCS
Catheter Site Haemorrhage PROTECT
Cerebral Haemorrhage PROTECT
Chest Pain ADReCS
Confusional State PROTECT
Conjunctival Haemorrhage PROTECT
Constipation PROTECT
Contusion PROTECT
Cough ADReCS
Diarrhoea ADReCS
Dizziness ADReCS
Duodenal Ulcer Haemorrhage PROTECT
Dyspepsia PROTECT
Dyspnoea PROTECT
Dyspnoea At Rest PROTECT
Dyspnoea Exertional PROTECT
Dyspnoea Paroxysmal Nocturnal PROTECT
Ear Haemorrhage PROTECT
Ecchymosis PROTECT
Epistaxis PROTECT
Eye Haemorrhage PROTECT
Fatigue ADReCS
Gastric Ulcer Haemorrhage PROTECT
Gastritis PROTECT
Gastrointestinal Haemorrhage PROTECT
Gastrointestinal Ulcer Haemorrhage PROTECT
Gingival Bleeding PROTECT
Gout ADReCS
Gynaecomastia ADReCS
Haemarthrosis PROTECT
Haematemesis PROTECT
Haematoma PROTECT
Haematuria PROTECT
Haemoptysis PROTECT
Haemorrhage ADReCS
Haemorrhage Intracranial PROTECT
Haemorrhage Subcutaneous PROTECT
Haemorrhage Urinary Tract PROTECT
Haemorrhagic Stroke PROTECT
Haemorrhoidal Haemorrhage PROTECT
Headache ADReCS
Hypersensitivity PROTECT
Hypertension ADReCS
Hyperuricaemia PROTECT
Hypotension ADReCS
Increased Tendency To Bruise PROTECT
Injection Site Haemorrhage PROTECT
Intestinal Haemorrhage PROTECT
Melaena PROTECT
Metrorrhagia PROTECT
Mouth Haemorrhage PROTECT
Nausea ADReCS
Nephropathy Toxic ADReCS
Nocturnal Dyspnoea PROTECT
Non-Cardiac Chest Pain ADReCS
Occult Blood PROTECT
Oliguria ADReCS
Paraesthesia PROTECT
Peptic Ulcer Haemorrhage PROTECT
Petechiae PROTECT
Post Procedural Haemorrhage PROTECT
Pruritus PROTECT
Puncture Site Haemorrhage PROTECT
Rash PROTECT
Rectal Haemorrhage PROTECT
Renal Failure Acute ADReCS
Renal Failure Chronic ADReCS
Retinal Haemorrhage PROTECT
Retroperitoneal Haemorrhage PROTECT
Skin Haemorrhage PROTECT
Subcutaneous Haematoma PROTECT
Traumatic Haematoma PROTECT
Traumatic Haemorrhage PROTECT
Vaginal Haemorrhage PROTECT
Ventricular Failure ADReCS
Vertigo PROTECT
Vessel Puncture Site Haematoma PROTECT
Vessel Puncture Site Haemorrhage PROTECT
Vomiting PROTECT
Wound Haemorrhage PROTECT

InAADR: Drug-Protein-ADRs database