InAADR

Drug Information

Drug Name: Solifenacin (242478-37-1)
PubChem ID: 154059
SMILES: C1CN2CCC1C(C2)OC(=O)N3CCC4=CC=CC=C4C3C5=CC=CC=C5
InchiKey: FBOUYBDGKBSUES-VXKWHMMOSA-N
Therapeutic Category: Cholinergic Agents, Cholinergic Antagonists, Muscarinic Antagonists, Neurotransmitter Agents, Urological Agents

Computed Drug Properties

Molecular Weight (dalton): 362.473
LogP: 3.8649
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 32.78

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Torsade De Pointes Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Dreams MetaADEDB
Abscess Jaw MetaADEDB
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acne Rosacea MetaADEDB
Acoustic Neuroma MetaADEDB
Acquired Oesophageal Web MetaADEDB
Actinomycosis MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Psychosis MetaADEDB
Adenopathy MetaADEDB
Adrenal Neoplasm MetaADEDB
Affective Disorder MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase ADReCS
Allergic Alveolitis MetaADEDB
Allergic Reaction ADReCS
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Alveolitis Fibrosing MetaADEDB
Alveoloplasty MetaADEDB
Amentia MetaADEDB
Anal Haemorrhage MetaADEDB
Anal Sphincter Atony MetaADEDB
Androgen Deficiency MetaADEDB
Angioedema ADReCS
Angiopathy ADReCS
Angle Closure Glaucoma MetaADEDB
Anhedonia MetaADEDB
Anorectal Disorder MetaADEDB
Anoxic Encephalopathy MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphagia MetaADEDB
Appetite Disorder MetaADEDB
Aptyalism MetaADEDB
Arthritis ADReCS
Arthritis Infective MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthropathy ADReCS
Artificial Crown Procedure MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase ADReCS
Asthenia ADReCS
Asthenopia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrioventricular Block Second Degree MetaADEDB
Atrophy MetaADEDB
Autoimmune Hepatitis MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Autologous Bone Marrow Transplantation Therapy MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Infection ADReCS
Belching MetaADEDB
Bence Jones Protein Urine MetaADEDB
Benign Ovarian Tumour MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Biopsy Bone Marrow MetaADEDB
Biopsy Colon MetaADEDB
Birth Defect MetaADEDB
Bladder Cancer MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bladder Spasm MetaADEDB
Bladder Suspension MetaADEDB
Bleeding Time Prolonged MetaADEDB
Blood Alkaline Phosphatase Decreased MetaADEDB
Blood Cholinesterase Decreased MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Product Transfusion MetaADEDB
Blood Prolactin Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Urine Present MetaADEDB
Blurred Vision MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Transplant MetaADEDB
Bone Operation MetaADEDB
Bone Pain MetaADEDB
Bone Spur MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Brain Oedema MetaADEDB
Breast Abscess MetaADEDB
Breast Cancer In Situ MetaADEDB
Breast Cancer Stage Ii MetaADEDB
Breast Cyst MetaADEDB
Breast Enlargement ADReCS
Breast Neoplasm MetaADEDB
Breast Pain MetaADEDB
Breast Pain Female ADReCS
Bronchial Hyperactivity MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchospasm ADReCS
Bundle Branch Block Right MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis ADReCS
Caesarean Section MetaADEDB
Candida Infection MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardiac Procedure Complication MetaADEDB
Cardiothoracic Ratio Increased MetaADEDB
Carotid Artery Disease MetaADEDB
Carotid Artery Occlusion MetaADEDB
Carpal Tunnel Decompression MetaADEDB
Cataract MetaADEDB
Cataract Operation MetaADEDB
Cellulitis Streptococcal MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebral Artery Embolism MetaADEDB
Chapped Lips MetaADEDB
Chills ADReCS
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat MetaADEDB
Colitis Ischaemic MetaADEDB
Colon Cancer Stage I MetaADEDB
Colonic Obstruction ADReCS
Colour Blindness Acquired MetaADEDB
Communication Disorder MetaADEDB
Compression Fracture MetaADEDB
Compulsive Shopping MetaADEDB
Confusional State ADReCS
Congenital Hypertrichosis MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Contracted Bladder MetaADEDB
Costochondritis MetaADEDB
Cough ADReCS
Crohn Disease ADReCS
Csf Protein MetaADEDB
Cystitis Noninfective MetaADEDB
Cystocele MetaADEDB
Debridement MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Delirium ADReCS
Dementia Of The Alzheimer Type With Delusions MetaADEDB
Dental Abscess MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Dependence MetaADEDB
Depression ADReCS
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Exfoliative ADReCS
Dermatitis Infected MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Dermographism MetaADEDB
Detached Retina MetaADEDB
Detached Retina Repair MetaADEDB
Dialysis Disequilibrium Syndrome MetaADEDB
Diplopia MetaADEDB
Disease Of Liver MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Ineffective MetaADEDB
Drug Interaction SIDER
Drug Intolerance MetaADEDB
Drug Screen Negative MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Throat MetaADEDB
Dysgeusia MetaADEDB
Dyspepsia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Dysuria ADReCS
Ear Discomfort MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Eczema Herpeticum MetaADEDB
Edema Extremities MetaADEDB
Edema Lower Limb ADReCS
Edema Of Lower Extremities SIDER
Effusion MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Prolonged ADReCS
Emotional Disorder MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Endometrial Hyperplasia MetaADEDB
Energy Increased MetaADEDB
Enuresis MetaADEDB
Epinephrine Increased MetaADEDB
Epistaxis MetaADEDB
Erythema Multiforme ADReCS
Esophageal Ulcer MetaADEDB
Excess Potassium MetaADEDB
Excessive Sleepiness MetaADEDB
Excessive Thirst MetaADEDB
Expressive Language Disorder MetaADEDB
Extremity Pain MetaADEDB
Eye Degenerative Disorder MetaADEDB
Eye Disorder SIDER
Face Injury MetaADEDB
Face Pain MetaADEDB
Faecal Vomiting MetaADEDB
Faecalith ADReCS
Faecaloma ADReCS
Family Stress MetaADEDB
Fascitis Plantar MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fear Of Eating MetaADEDB
Feeling Abnormal ADReCS
Feeling Guilty MetaADEDB
Fibromyalgia MetaADEDB
Fistula MetaADEDB
Fistula Repair MetaADEDB
Flatulence ADReCS
Food Interaction SIDER
Foot Operation MetaADEDB
Fractured Pelvis Nos MetaADEDB
Frustration MetaADEDB
Fungal Infection ADReCS
Gait Spastic MetaADEDB
Gamma-Glutamyltransferase ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Polyps MetaADEDB
Gastric Ulcer ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Fistula ADReCS
Gastrointestinal Obstruction MetaADEDB
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gingival Disorder MetaADEDB
Glaucoma ADReCS
Haemangioma Congenital MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Haemorrhoids ADReCS
Hallucination ADReCS
Halo Vision MetaADEDB
Headache ADReCS
Heart Rate Abnormal MetaADEDB
Heart Valve Incompetence MetaADEDB
Heat Illness MetaADEDB
Heat Stroke MetaADEDB
Hemianopia MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Lesion MetaADEDB
Hernia Hiatus Repair MetaADEDB
Herpes Zoster MetaADEDB
Hesitancy MetaADEDB
Hiccough MetaADEDB
High Blood Pressure MetaADEDB
Hydrocephalus MetaADEDB
Hydronephrosis MetaADEDB
Hyperaesthesia MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperkalaemia ADReCS
Hyperkinetic Heart Syndrome MetaADEDB
Hyperlipaemia MetaADEDB
Hyperparathyroidism Secondary MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypoglycaemic Encephalopathy MetaADEDB
Hypomagnesaemia ADReCS
Hypothyroid MetaADEDB
Hypovolaemia MetaADEDB
Hypoxia MetaADEDB
Hysterectomy MetaADEDB
Hysterosalpingo-Oophorectomy MetaADEDB
Ileus ADReCS
Impaired Gastric Emptying MetaADEDB
Incision Site Pain MetaADEDB
Incontinence MetaADEDB
Increased Appetite MetaADEDB
Infantile Spasms MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Infective Spondylitis MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Influenza Like Illness ADReCS
Ingrowing Nail MetaADEDB
Injection Site Discolouration MetaADEDB
Injection Site Inflammation ADReCS
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Injury Asphyxiation MetaADEDB
Insomnia ADReCS
Insulin-Like Growth Factor Increased MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intervertebral Disc Operation MetaADEDB
Intestinal Obstruction ADReCS
Intestinal Polyp MetaADEDB
Intraocular Lens Implant MetaADEDB
Ischaemia MetaADEDB
Jaw Operation MetaADEDB
Joint Arthroplasty MetaADEDB
Joint Contracture MetaADEDB
Keratitis Fungal MetaADEDB
Kidney Pain MetaADEDB
Knee Arthroplasty MetaADEDB
Kyphosis MetaADEDB
Lacrimation Increased MetaADEDB
Lacunar Infarction MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Laryngitis ADReCS
Leukocyturia MetaADEDB
Lichen Planus MetaADEDB
Ligament Rupture MetaADEDB
Ligament Sprain MetaADEDB
Lip Exfoliation MetaADEDB
Liver Disorder ADReCS
Liver Function Test Abnormal ADReCS
Long Qt Syndrome MetaADEDB
Loose Tooth MetaADEDB
Lung Consolidation MetaADEDB
Lung Infection MetaADEDB
Macula Lutea Degeneration MetaADEDB
Maculopathy MetaADEDB
Major Depression MetaADEDB
Malignant Melanoma MetaADEDB
Marasmus MetaADEDB
Mastication Disorder MetaADEDB
Mediastinal Disorder SIDER
Medical Device Change MetaADEDB
Melaena ADReCS
Meniscus Lesion MetaADEDB
Mental Disorder SIDER
Mental Status Changes MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Spine MetaADEDB
Micturition Frequency Decreased MetaADEDB
Micturition Urgency MetaADEDB
Mini Mental Status Examination MetaADEDB
Motion Sickness MetaADEDB
Mouth Pain MetaADEDB
Mucosal Inflammation MetaADEDB
Multiple Injuries MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Myalgia ADReCS
Myeloma Recurrence MetaADEDB
Nail Disorder ADReCS
Nasal Dryness MetaADEDB
Nausea ADReCS
Negative Thoughts MetaADEDB
Nephrolithiasis ADReCS
Nerve Block MetaADEDB
Nervous System Disorder SIDER
Neural Tube Defect MetaADEDB
Neurogenic Bladder MetaADEDB
Neurosis MetaADEDB
Nocturia MetaADEDB
Obstruction ADReCS
Obstructive Airways Disorder MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oligodendroglioma MetaADEDB
Oliguria MetaADEDB
Open Reduction Of Fracture MetaADEDB
Optic Nerve Injury MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Discomfort MetaADEDB
Oral Disorder ADReCS
Oral Fungal Infection MetaADEDB
Oral Herpes MetaADEDB
Oral Mucosa Erosion MetaADEDB
Oral Mucosal Erythema MetaADEDB
Oral Surgery MetaADEDB
Oropharyngeal Plaque MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteoporosis Postmenopausal MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Painful Respiration MetaADEDB
Palatal Oedema MetaADEDB
Pancreatitis ADReCS
Papilloma MetaADEDB
Paradoxical Drug Reaction MetaADEDB
Paraesthesia ADReCS
Paraparesis MetaADEDB
Parasomnia MetaADEDB
Parathyroidectomy MetaADEDB
Paresis Anal Sphincter MetaADEDB
Parkinson MetaADEDB
Paronychia MetaADEDB
Parotitis MetaADEDB
Patella Fracture MetaADEDB
Penile Discharge MetaADEDB
Periarthritis MetaADEDB
Periorbital Oedema ADReCS
Ph Urine Increased MetaADEDB
Phantom Pain ADReCS
Pharyngitis ADReCS
Pharyngolaryngeal Discomfort MetaADEDB
Physical Disability MetaADEDB
Placental Disorder MetaADEDB
Plastic Surgery MetaADEDB
Pleural Fibrosis MetaADEDB
Pollakiuria MetaADEDB
Polyneuropathy MetaADEDB
Post Procedural Dizziness MetaADEDB
Postmenopause MetaADEDB
Postoperative Thrombosis MetaADEDB
Postoperative Wound Complication MetaADEDB
Postrenal Failure MetaADEDB
Posture Abnormal MetaADEDB
Pre-Eclampsia MetaADEDB
Precancerous Cells Present MetaADEDB
Presbyacusis MetaADEDB
Primary Sequestrum MetaADEDB
Procedural Pain MetaADEDB
Progesterone Receptor Assay MetaADEDB
Prostatitis MetaADEDB
Proteus Infection MetaADEDB
Prothrombin Level Decreased ADReCS
Pruritus ADReCS
Pseudomonal Sepsis MetaADEDB
Punctate Keratitis MetaADEDB
Purpura ADReCS
Purulent Discharge MetaADEDB
Pyelonephritis ADReCS
Pyelonephritis Acute MetaADEDB
Pyrexia ADReCS
Qrs Axis Abnormal MetaADEDB
Quality Of Life Decreased MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Reaction To Drug Excipient MetaADEDB
Rectal Haemorrhage ADReCS
Rectal Polyp MetaADEDB
Rectal Prolapse MetaADEDB
Rectal Tenesmus ADReCS
Rectal Ulcer MetaADEDB
Red Cell Distribution Width Increased MetaADEDB
Reflux Esophagitis MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Renal Cyst MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Impairment ADReCS
Residual Urine Volume Increased MetaADEDB
Respiratory Disorder ADReCS
Respiratory Tract Infection ADReCS
Resuscitation MetaADEDB
Retinal Exudates MetaADEDB
Retinal Tear MetaADEDB
Rib Fracture MetaADEDB
Saliva Altered MetaADEDB
Salivary Gland Inflammation MetaADEDB
Sensory Loss ADReCS
Septal Panniculitis MetaADEDB
Shoulder Operation MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinus Arrest MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Disorder MetaADEDB
Skeletal Injury MetaADEDB
Skin Disorder ADReCS
Skin Induration MetaADEDB
Skin Injury MetaADEDB
Skin Lesion MetaADEDB
Skull Fracture MetaADEDB
Sleep Apnea MetaADEDB
Sleep Talking MetaADEDB
Small For Dates Baby MetaADEDB
Soft Tissue Inflammation MetaADEDB
Soft Tissue Injuries MetaADEDB
Somnolence ADReCS
Spinal Column Stenosis MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Decompression MetaADEDB
Spinal Fusion Surgery MetaADEDB
Spinal Laminectomy MetaADEDB
Spinal Nerve Stimulator Implantation MetaADEDB
Spinal Osteoarthritis MetaADEDB
Steatorrhoea ADReCS
Stem Cell Transplant MetaADEDB
Stress MetaADEDB
Stress Incontinence MetaADEDB
Surgical Procedure Repeated MetaADEDB
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tardive Dyskinesia MetaADEDB
Tendon Graft MetaADEDB
Tendon Injury MetaADEDB
Thalamic Infarction MetaADEDB
Thirst ADReCS
Thrombotic Stroke MetaADEDB
Tinea Versicolor MetaADEDB
Tongue Black Hairy MetaADEDB
Tongue Discolouration MetaADEDB
Tongue Dry MetaADEDB
Tonsillectomy MetaADEDB
Tooth Deposit MetaADEDB
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Impacted ADReCS
Tooth Infection MetaADEDB
Tooth Loss MetaADEDB
Torsade De Pointes ADReCS
Underdose MetaADEDB
Unevaluable Event MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urethral Disorder SIDER
Urethral Obstruction MetaADEDB
Urge Incontinence MetaADEDB
Urinary Bladder Rupture MetaADEDB
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urinary Tract Infection Enterococcal MetaADEDB
Urine Abnormality ADReCS
Urticaria ADReCS
Vaginal Abscess MetaADEDB
Vaginal Infection ADReCS
Vaginal Ulceration MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Vasodilatation ADReCS
Vision Blurred ADReCS
Visual Disturbance MetaADEDB
Visual Field Defect ADReCS
Vomiting ADReCS
Weight Gain MetaADEDB
Wheeze MetaADEDB
Withdrawal Bleed MetaADEDB
Wound Drainage MetaADEDB
Zinc Deficiency MetaADEDB

InAADR: Drug-Protein-ADRs database