InAADR

Drug Information

Drug Name: Sevoflurane (28523-86-6)
PubChem ID: 5206
SMILES: C(OC(C(F)(F)F)C(F)(F)F)F
InchiKey: DFEYYRMXOJXZRJ-UHFFFAOYSA-N
Therapeutic Category: Anesthetics, Central Nervous System Agents, Central Nervous System Depressants, Hematologic Agents, Platelet Aggregation Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 200.053
LogP: 2.4232
Ring Count: 0
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 9.23

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abscess Drainage MetaADEDB
Acidosis ADReCS
Activated Partial Thromboplastin Time Abnormal MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Right Ventricular Failure MetaADEDB
Adrenal Insufficiency MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Airway Burns MetaADEDB
Airway Complication Of Anaesthesia MetaADEDB
Airway Obstruction Nos SIDER
Akinesia MetaADEDB
Alanine Aminotransferase Increased ADReCS
Albuminuria ADReCS
Alkalosis Hypochloraemic MetaADEDB
Alveolar Proteinosis MetaADEDB
Amblyopia ADReCS
Anaemia Postoperative MetaADEDB
Anaesthetic Complication MetaADEDB
Anaesthetic Complication Cardiac MetaADEDB
Anaesthetic Complication Neurological MetaADEDB
Anaesthetic Complication Pulmonary MetaADEDB
Anaesthetic Complication Vascular MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Angle Closure Glaucoma MetaADEDB
Anisocoria MetaADEDB
Antibody Test MetaADEDB
Anticholinergic Syndrome MetaADEDB
Antinuclear Antibody MetaADEDB
Apallic Syndrome MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Arrhythmia ADReCS
Arrhythmia Supraventricular ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriospasm Coronary MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Arrhythmia SIDER
Atrial Ectopic Beats MetaADEDB
Atrial Fibrillation ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block SIDER
Atrioventricular Block Complete ADReCS
Atrioventricular Block Second Degree ADReCS
B Precursor Type Acute Leukaemia MetaADEDB
Base Excess MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Abnormal ADReCS
Blood Calcium MetaADEDB
Blood Corticotrophin Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Abnormal ADReCS
Blood Disorder MetaADEDB
Blood Gases Abnormal MetaADEDB
Blood Glucose Increased ADReCS
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Magnesium Increased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Urea MetaADEDB
Blood Urea Abnormal ADReCS
Body Temperature Decreased ADReCS
Body Temperature Increased ADReCS
Bone Disorder ADReCS
Bradycardia ADReCS
Bradycardia Foetal MetaADEDB
Bradypnoea MetaADEDB
Brain Damage MetaADEDB
Brain Death MetaADEDB
Brain Stem Haemorrhage MetaADEDB
Breath Holding ADReCS
Breath Holding Attack SIDER
Bronchial Injury MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchomalacia MetaADEDB
Bronchospasm ADReCS
Brugada Syndrome MetaADEDB
Bulbar Palsy MetaADEDB
Bundle Branch Block MetaADEDB
Bundle Branch Block Left MetaADEDB
Caesarean Section MetaADEDB
Calcium Ionised MetaADEDB
Carbon Monoxide Poisoning MetaADEDB
Carboxyhaemoglobin Increased MetaADEDB
Carboxyhaemoglobinaemia MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Massage MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardio-Respiratory Distress MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Disorder MetaADEDB
Cardiovascular Insufficiency MetaADEDB
Carotid Sinus Syndrome MetaADEDB
Catatonia MetaADEDB
Catheter Removal MetaADEDB
Central Venous Pressure Decreased MetaADEDB
Central Venous Pressure Increased MetaADEDB
Cerebral Disorder MetaADEDB
Cerebral Hypoperfusion MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ischaemia MetaADEDB
Cheilitis MetaADEDB
Chemical Injury MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Chromaturia MetaADEDB
Clonus MetaADEDB
Clotting MetaADEDB
Coagulation Factor V Level Decreased MetaADEDB
Coma MetaADEDB
Complications Of Transplant Surgery MetaADEDB
Confusional State ADReCS
Congenital Tracheomalacia MetaADEDB
Conjunctivitis ADReCS
Continuous Haemodiafiltration MetaADEDB
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Cranial Nerve Disorder MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Creatinine Renal Clearance Increased MetaADEDB
Critical Illness Polyneuropathy MetaADEDB
Crying ADReCS
Csf Pressure Increased MetaADEDB
Cyanosis MetaADEDB
Cytokine Release Syndrome MetaADEDB
Dacryostenosis Acquired MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Dermatomyositis MetaADEDB
Device Failure MetaADEDB
Dilatation Ventricular MetaADEDB
Disease Of Liver MetaADEDB
Dizziness ADReCS
Drug Effect Prolonged MetaADEDB
Drug Interaction MetaADEDB
Drug Tolerance MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspnoea ADReCS
Dystonia MetaADEDB
Dystrophia Myotonica MetaADEDB
Dysuria ADReCS
Echocardiogram Abnormal MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Prolonged SIDER
Electrocardiogram Repolarisation Abnormality MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Electrocardiogram St Segment Depression ADReCS
Electrocardiogram St Segment Elevation MetaADEDB
Electrocardiogram St-T Segment Depression MetaADEDB
Electrocardiogram T Wave Amplitude Decreased MetaADEDB
Electrocardiogram T Wave Inversion ADReCS
Electromechanical Dissociation MetaADEDB
End-Tidal Co2 Increased MetaADEDB
Endotracheal Intubation Complication MetaADEDB
Enlarged Spleen MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epidural Abscess MetaADEDB
Epidural Hematoma MetaADEDB
Epiglottic Oedema MetaADEDB
Excess Potassium MetaADEDB
Extrasystoles ADReCS
Extrasystoles Ventricular MetaADEDB
Eye Rolling MetaADEDB
Eyelid Oedema ADReCS
Facial Palsy MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Fluorosis ADReCS
Foetal Acidosis MetaADEDB
Foetal Heart Rate Decreased MetaADEDB
Gastric Mucosal Lesion MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
Generalised Erythema MetaADEDB
Global Amnesia MetaADEDB
Globulinuria MetaADEDB
Glossectomy MetaADEDB
Glossoptosis MetaADEDB
Glycosuria ADReCS
Grip Strength MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemolysis MetaADEDB
Haemorrhage ADReCS
Haemorrhagic Diathesis MetaADEDB
Head Circumference Abnormal MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hemiparesis MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Necrosis ADReCS
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatotoxicity MetaADEDB
Hiccups ADReCS
Hoffmann Sign MetaADEDB
Holmes-Adie Pupil MetaADEDB
Hydrocephalus MetaADEDB
Hyperbilirubinaemia ADReCS
Hypercapnia MetaADEDB
Hyperglycaemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperthermia ADReCS
Hyperthermia Malignant ADReCS
Hypertonia ADReCS
Hyperventilation ADReCS
Hypoglossal Nerve Disorder MetaADEDB
Hypophosphataemia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Hypotonia MetaADEDB
Hypoventilation ADReCS
Hypoxia ADReCS
Hypoxic Encephalopathy MetaADEDB
Iatrogenic Injury MetaADEDB
Idiosyncratic Drug Reaction MetaADEDB
Incorrect Drug Administration Rate MetaADEDB
Increased Bronchial Secretion ADReCS
Infantile Apnoeic Attack MetaADEDB
Injection Site Inflammation MetaADEDB
Insomnia ADReCS
Intubation MetaADEDB
Ischaemia MetaADEDB
Jaundice ADReCS
Labile Blood Pressure MetaADEDB
Laryngospasm ADReCS
Left Atrial Dilatation MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leg Amputation MetaADEDB
Leukocytosis ADReCS
Leukoencephalopathy MetaADEDB
Light Anaesthesia MetaADEDB
Liver Function Test Abnormal ADReCS
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Low Cardiac Output Syndrome MetaADEDB
Lung Edema MetaADEDB
Lymphocele MetaADEDB
Lymphocytes Decreased MetaADEDB
Mechanical Ventilation MetaADEDB
Medical Device Complication MetaADEDB
Metabolic Disorder MetaADEDB
Migraine With Aura MetaADEDB
Miosis MetaADEDB
Motor Dysfunction MetaADEDB
Movement Disorder ADReCS
Muscle Necrosis MetaADEDB
Muscle Rigidity ADReCS
Musculoskeletal Stiffness MetaADEDB
Myoclonic Epilepsy MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobin Urine Present MetaADEDB
Myoglobinaemia MetaADEDB
Myotonia MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Neonatal Asphyxia MetaADEDB
Nephritis ADReCS
Nephrogenic Anaemia MetaADEDB
Nervousness ADReCS
Neuromuscular Block Prolonged MetaADEDB
No Therapeutic Response MetaADEDB
Nodule MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Nosocomial Infection MetaADEDB
Nystagmus MetaADEDB
Obstruction ADReCS
Obstructive Airways Disorder ADReCS
Oedema ADReCS
Oliguria ADReCS
Operative Haemorrhage MetaADEDB
Ophthalmoplegia MetaADEDB
Organising Pneumonia MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pancreatitis ADReCS
Parkinson MetaADEDB
Parotid Gland Enlargement MetaADEDB
Parotitis MetaADEDB
Pco2 Decreased MetaADEDB
Pco2 Increased MetaADEDB
Pedal Pulse Absent MetaADEDB
Penile Vascular Disorder MetaADEDB
Peripheral Ischaemia MetaADEDB
Peripheral Nerve Injury MetaADEDB
Phaeochromocytoma MetaADEDB
Pharyngitis ADReCS
Pityriasis MetaADEDB
Pneumonia Respiratory Syncytial Viral MetaADEDB
Po2 Decreased MetaADEDB
Poor Peripheral Circulation MetaADEDB
Poor Quality Sleep MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Fever MetaADEDB
Postoperative Respiratory Distress MetaADEDB
Premature Recovery From Anaesthesia MetaADEDB
Prinzmetal Angina MetaADEDB
Procalcitonin MetaADEDB
Procedural Complication MetaADEDB
Procedural Hypertension MetaADEDB
Procedural Hypotension MetaADEDB
Procedural Vomiting MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Congestion MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Pustular Psoriasis MetaADEDB
Pyothorax MetaADEDB
Pyrexia ADReCS
Rales MetaADEDB
Rash ADReCS
Renal Failure ADReCS
Respiration Abnormal MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Failure ADReCS
Resuscitation MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rhabdomyolysis MetaADEDB
Right Atrial Pressure Increased MetaADEDB
Right Heart Failure MetaADEDB
Risus Sardonicus MetaADEDB
Salivary Gland Enlargement MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Screaming MetaADEDB
Scrotal Swelling MetaADEDB
Seizures SIDER
Sensorimotor Disorder MetaADEDB
Sensory Loss MetaADEDB
Shivering ADReCS
Shock ADReCS
Sinoatrial Block MetaADEDB
Sinus Arrest MetaADEDB
Sinus Bradycardia MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Small Intestinal Perforation MetaADEDB
Somnolence ADReCS
Spinal Cord Infarction MetaADEDB
Sputum Increased ADReCS
Sputum Retention MetaADEDB
Staring MetaADEDB
Status Epilepticus MetaADEDB
Stress Cardiomyopathy MetaADEDB
Stridor ADReCS
Subarachnoid Haemorrhage MetaADEDB
Supraventricular Extrasystoles ADReCS
Supraventricular Tachycardia MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Therapy Non-Responder MetaADEDB
Threatened Labour MetaADEDB
Thrombocytopenia ADReCS
Tongue Disorder MetaADEDB
Tongue Neoplasm MetaADEDB
Tongue Paralysis MetaADEDB
Tonic Clonic Movements MetaADEDB
Torsade De Pointes ADReCS
Toxic Skin Eruption MetaADEDB
Tracheal Disorder MetaADEDB
Tracheal Stenosis MetaADEDB
Transurethral Resection Syndrome MetaADEDB
Tryptase Increased MetaADEDB
Tubulointerstitial Nephritis ADReCS
Tumour Lysis Syndrome MetaADEDB
Underdose MetaADEDB
Unresponsive To Stimuli MetaADEDB
Unwanted Awareness During Anaesthesia MetaADEDB
Upper Airway Obstruction MetaADEDB
Ureteral Disorder MetaADEDB
Urethral Disorder SIDER
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urination Impaired ADReCS
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urine Ketone Body Present MetaADEDB
Urticaria ADReCS
Vascular Injury MetaADEDB
Ventricular Bigeminy SIDER
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation ADReCS
Ventricular Hypokinesia MetaADEDB
Ventricular Tachycardia ADReCS
Ventriculo-Peritoneal Shunt MetaADEDB
Vital Capacity Decreased MetaADEDB
Vocal Cord Disorder MetaADEDB
Vomiting ADReCS
Wheeze MetaADEDB
Wheezing ADReCS
White Blood Cell Count Increased ADReCS
Wound Haemorrhage MetaADEDB

InAADR: Drug-Protein-ADRs database