InAADR

Drug Information

Drug Name: Ropivacaine (84057-95-4)
PubChem ID: 175805
SMILES: CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C
InchiKey: ZKMNUMMKYBVTFN-HNNXBMFYSA-N
Therapeutic Category: Anesthetics, Central Nervous System Agents, Central Nervous System Depressants, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 274.408
LogP: 3.50644
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 32.34

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cavity Drainage MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Behaviour MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Labour SIDER
Abscess ADReCS
Accidental Injury ADReCS
Acidosis ADReCS
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adams-Stokes Syndrome MetaADEDB
Adenoviral Haemorrhagic Cystitis MetaADEDB
Adverse Drug Effect MetaADEDB
Affect Lability ADReCS
Agitation ADReCS
Akinesia MetaADEDB
Alanine Aminotransferase Increased SIDER
Albuminuria ADReCS
Als MetaADEDB
Altered State Of Consciousness ADReCS
Amnesia ADReCS
Amniotic Fluid Embolus MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaesthetic Complication MetaADEDB
Anaphylactic Shock ADReCS
Angiitis MetaADEDB
Angioedema ADReCS
Anorectal Discomfort ADReCS
Anorectal Disorder MetaADEDB
Anterior Spinal Artery Syndrome ADReCS
Anxiety ADReCS
Aortic Stenosis MetaADEDB
Apgar Score Low ADReCS
Apnoea ADReCS
Application Site Reaction ADReCS
Arachnoiditis ADReCS
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia ADReCS
Aspartate Aminotransferase Increased SIDER
Asthenia ADReCS
Asystole MetaADEDB
Atelectasis ADReCS
Atrial Ectopic Beats MetaADEDB
Atrial Fibrillation ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block ADReCS
Automatism MetaADEDB
Axonal Neuropathy MetaADEDB
Back Pain ADReCS
Bladder Disorder MetaADEDB
Bleeding Vaginal MetaADEDB
Block Heart SIDER
Blood Alkaline Phosphatase MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Glucose Fluctuation MetaADEDB
Blood In Urine MetaADEDB
Blood Ph Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Urea Decreased SIDER
Body Temperature Decreased ADReCS
Body Temperature Increased ADReCS
Bradycardia ADReCS
Bradycardia Foetal ADReCS
Brain Stem Infarction MetaADEDB
Brain Stem Syndrome MetaADEDB
Breast Disorder ADReCS
Bronchospasm ADReCS
Bulbar Palsy MetaADEDB
Bundle Branch Block MetaADEDB
Cardiac Arrest ADReCS
Cardiac Death MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Massage MetaADEDB
Cardiac Output Decreased ADReCS
Cardiogenic Shock MetaADEDB
Catatonia MetaADEDB
Cauda Equina Syndrome ADReCS
Cellulitis Orbital MetaADEDB
Cervicobrachial Syndrome MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Chondrolysis MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clonus MetaADEDB
Clostridial Infection MetaADEDB
Coagulation Factor Increased MetaADEDB
Cold Extremities MetaADEDB
Coma ADReCS
Confusional State ADReCS
Congenital Pyelocaliectasis MetaADEDB
Constipation ADReCS
Constricted Pupils SIDER
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Cranial Nerve Paralysis ADReCS
Creatine Phosphokinase Increased SIDER
Crying MetaADEDB
Cyanosis MetaADEDB
Cystitis Viral MetaADEDB
Deafness Neurosensory MetaADEDB
Decubitus Ulcer MetaADEDB
Deep Vein Thrombosis ADReCS
Delayed Recovery From Anaesthesia MetaADEDB
Delusion Of Grandeur MetaADEDB
Demyelination MetaADEDB
Denervation Atrophy MetaADEDB
Dental Plaque MetaADEDB
Dependence On Enabling Machine Or Device MetaADEDB
Depressed Level Of Consciousness ADReCS
Dermatitis ADReCS
Diaphragmatic Paralysis MetaADEDB
Diarrhoea ADReCS
Diffuse Axonal Injury MetaADEDB
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Diplegia ADReCS
Discomfort ADReCS
Disease Progression ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Exposure During Pregnancy MetaADEDB
Drug Toxicity MetaADEDB
Duodenal Perforation MetaADEDB
Dyskinesia ADReCS
Dyslalia MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Effusion ADReCS
Electrocardiogram Abnormal ADReCS
Electrocardiogram Q Waves MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Electrocardiogram St Segment SIDER
Electrocardiogram St Segment Abnormal ADReCS
Electrocardiogram T Wave Amplitude Increased MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Electromechanical Dissociation MetaADEDB
Electromyogram Abnormal MetaADEDB
Embolism ADReCS
Endocrine Disorder SIDER
Endoscopy MetaADEDB
Enlargement Abdomen SIDER
Eosinophil Percentage Abnormal MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epidural Abscess MetaADEDB
Epidural Hematoma MetaADEDB
Epilepsy MetaADEDB
Erythema ADReCS
Excitement SIDER
Extradural Abscess ADReCS
Extrasystoles ADReCS
Eyelid Ptosis ADReCS
Faecal Impaction MetaADEDB
Faecal Incontinence ADReCS
Failed Induction Of Labour ADReCS
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Fever Neonatal ADReCS
Flail Chest MetaADEDB
Foetal Distress Syndrome ADReCS
Gas Gangrene MetaADEDB
Gastrointestinal Pain ADReCS
Glossoptosis MetaADEDB
Haematoma ADReCS
Haematuria ADReCS
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Hallucination ADReCS
Headache ADReCS
Hearing Impaired ADReCS
Heart Rate Increased MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Function Abnormal ADReCS
Hernia Inguinal MetaADEDB
Hormone Level Abnormal SIDER
Horner Syndrome ADReCS
Humerus Fracture MetaADEDB
Hyperaesthesia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypoaesthesia ADReCS
Hypocalcaemia ADReCS
Hypoglossal Nerve Disorder MetaADEDB
Hypoglycaemia ADReCS
Hypoglycaemia Neonatal ADReCS
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hypomagnesaemia ADReCS
Hypoproteinaemia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Hypotonia ADReCS
Hypoxia ADReCS
Iatrogenic Injury MetaADEDB
Ill-Defined Disorder ADReCS
Illusion MetaADEDB
Impaired Work Ability MetaADEDB
Incontinence ADReCS
Incorrect Route Of Drug Administration MetaADEDB
Infarction ADReCS
Infection ADReCS
Inflammation ADReCS
Injection Site Infection MetaADEDB
Injection Site Inflammation ADReCS
Injection Site Movement Impairment MetaADEDB
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Injection Site Thrombosis MetaADEDB
Insomnia ADReCS
Intervertebral Disc Herniation MetaADEDB
Jaundice ADReCS
Jaundice Neonatal ADReCS
Joint Ankylosis MetaADEDB
Joint Injury MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Keloid Scar MetaADEDB
Labour Complication ADReCS
Laparotomy MetaADEDB
Laryngeal Oedema ADReCS
Left Ventricular Dysfunction MetaADEDB
Lesion Of Sciatic Nerve MetaADEDB
Leukocytosis ADReCS
Logorrhoea MetaADEDB
Loss Of Consciousness ADReCS
Low Cardiac Output Syndrome MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lymphocyte Count Abnormal MetaADEDB
Lymphocytes Decreased MetaADEDB
Maculopathy ADReCS
Malaise ADReCS
Meningeal Irritation MetaADEDB
Meningism ADReCS
Meningitis ADReCS
Mental Disorder SIDER
Metabolic Disorder SIDER
Micturition Disorder ADReCS
Miosis ADReCS
Mononeuritis MetaADEDB
Monoplegia ADReCS
Mood Swings ADReCS
Motor Dysfunction MetaADEDB
Movement Disorder MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder MetaADEDB
Musculoskeletal Pain MetaADEDB
Myalgia ADReCS
Myelitis MetaADEDB
Myelopathy MetaADEDB
Myocardial Infarction ADReCS
Nausea ADReCS
Neonatal Disorder ADReCS
Neonatal Infection ADReCS
Neonatal Respiratory Distress Syndrome MetaADEDB
Neonatal Respiratory Failure MetaADEDB
Neonatal Tachypnoea ADReCS
Nerve Block MetaADEDB
Nerve Degeneration MetaADEDB
Nerve Paralysis SIDER
Nerve Root Injury MetaADEDB
Nervousness ADReCS
Neuralgic Amyotrophy MetaADEDB
Neuromuscular Block Prolonged MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Nightmare ADReCS
Normal Newborn MetaADEDB
Nosocomial Infection MetaADEDB
Obstruction ADReCS
Oculomucocutaneous Syndrome MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oliguria ADReCS
Operative Haemorrhage MetaADEDB
Oral Mucosal Erythema MetaADEDB
Orthostatic Hypotension ADReCS
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Palsies MetaADEDB
Panniculitis MetaADEDB
Paraesthesia ADReCS
Paraesthesia Circumoral MetaADEDB
Paralysis ADReCS
Paraparesis MetaADEDB
Paraplegia ADReCS
Paresis ADReCS
Pco2 Decreased MetaADEDB
Perineal Repair Breakdown MetaADEDB
Peripartum Cardiomyopathy MetaADEDB
Peripheral Nerve Injury MetaADEDB
Peripheral Nerve Palsy MetaADEDB
Peripheral Paralysis MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Phantom Pain MetaADEDB
Phlebitis ADReCS
Phosphatase Alkaline Increased SIDER
Phrenic Nerve Paralysis MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pleurisy MetaADEDB
Pneumomediastinum MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumopericardium MetaADEDB
Polyuria MetaADEDB
Post Procedural Bile Leak MetaADEDB
Post Procedural Complication ADReCS
Post Procedural Haematoma MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Post Procedural Oedema MetaADEDB
Post Procedural Pain MetaADEDB
Postoperative Complications Nos SIDER
Postoperative Infection MetaADEDB
Postoperative Pain SIDER
Postpartum Haemorrhage SIDER
Presyncope ADReCS
Procedural Complication MetaADEDB
Procedural Pain ADReCS
Proctalgia ADReCS
Product Quality Issue MetaADEDB
Prolonged Labour ADReCS
Prothrombin Level Decreased ADReCS
Pruritus ADReCS
Pseudomonas Infection MetaADEDB
Ptosis SIDER
Pulmonary Embolism ADReCS
Pulmonary Infarction MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Pyuria ADReCS
Quadriplegia MetaADEDB
Radicular Syndrome MetaADEDB
Rales ADReCS
Rash ADReCS
Rectal Tenesmus ADReCS
Renal Function Test Abnormal MetaADEDB
Renal Tubular Necrosis MetaADEDB
Repetitive Speech MetaADEDB
Respiratory Arrest ADReCS
Respiratory Disorder ADReCS
Respiratory Disorder Neonatal ADReCS
Respiratory Failure ADReCS
Respiratory Insufficiency SIDER
Respiratory Paralysis ADReCS
Respiratory Rate Increased MetaADEDB
Retinitis Pigmentosa ADReCS
Retroperitoneal Haematoma MetaADEDB
Retroperitoneal Lymphadenopathy MetaADEDB
Rhinitis ADReCS
Rigors SIDER
Scrotal Infection MetaADEDB
Sensorimotor Disorder MetaADEDB
Sensory Disturbance MetaADEDB
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sinoatrial Block MetaADEDB
Sinus Arrest MetaADEDB
Skin Disorder ADReCS
Sneezing ADReCS
Somnolence ADReCS
Spinal Anaesthesia MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Cord Infarction MetaADEDB
Spinal Cord Ischaemia MetaADEDB
Spinal Cord Paralysis MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spinning Sensation MetaADEDB
Splenic Infarction MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stress Cardiomyopathy MetaADEDB
Stupor ADReCS
Subdural Effusion MetaADEDB
Sudden Infant Death Syndrome MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Sweating SIDER
Sweating Increased SIDER
Syncope ADReCS
Syncope Vasovagal ADReCS
Tachycardia ADReCS
Tachycardia Foetal ADReCS
Tachypnoea ADReCS
Tension ADReCS
Therapeutic Embolisation MetaADEDB
Therapeutic Response Unexpected ADReCS
Therapy Non-Responder MetaADEDB
Threatened Labour MetaADEDB
Thrombocytopenia ADReCS
Thrombocytosis ADReCS
Thrombosis ADReCS
Tinnitus ADReCS
Tongue Paralysis MetaADEDB
Tooth Discolouration MetaADEDB
Torsade De Pointes MetaADEDB
Tremor ADReCS
Unexpected Therapeutic Effect SIDER
Urethral Disorder SIDER
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urinary Tract Infection Staphylococcal MetaADEDB
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urticaria ADReCS
Uterine Atony ADReCS
Uterine Hypotonus ADReCS
Uterovaginal Prolapse ADReCS
Vacuum Extractor Delivery MetaADEDB
Vaginal Laceration MetaADEDB
Vascular Purpura ADReCS
Vascular Resistance Systemic Decreased MetaADEDB
Vasoconstriction MetaADEDB
Venous Thrombosis ADReCS
Ventricular Fibrillation ADReCS
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Vomiting Neonatal ADReCS
Weakness SIDER
Wound Complication MetaADEDB
Wound Infection Staphylococcal MetaADEDB
Wound Secretion MetaADEDB
Wound Treatment MetaADEDB

InAADR: Drug-Protein-ADRs database