InAADR

Drug Information

Drug Name: Repaglinide (135062-02-1)
PubChem ID: 65981
SMILES: CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
InchiKey: FAEKWTJYAYMJKF-QHCPKHFHSA-N
Therapeutic Category: Hypoglycemic Agents

Computed Drug Properties

Molecular Weight (dalton): 452.595
LogP: 5.2199
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 78.87

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Hypoglycemia Interactions between grapefruit juice and cardiovascular drugs

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Infection MetaADEDB
Abdominal Pain PROTECT
Abdominal Rigidity MetaADEDB
Abscess MetaADEDB
Abscess Oral MetaADEDB
Abuse MetaADEDB
Acetonaemia MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acne MetaADEDB
Actinomycosis MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Otitis Media MetaADEDB
Acute Pancreatitis MetaADEDB
Adrenal Insufficiency MetaADEDB
Afib MetaADEDB
Albumin Globulin Ratio Abnormal MetaADEDB
Allergic Vasculitis MetaADEDB
Allergy ADReCS
Alopecia ADReCS
Anaemia ADReCS
Anaemia Of Malignant Disease MetaADEDB
Anaesthesia MetaADEDB
Anaphylactic Reaction PROTECT
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Angiitis MetaADEDB
Angina Pectoris ADReCS
Angioedema MetaADEDB
Angioplasty MetaADEDB
Anhedonia MetaADEDB
Anorexia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Anuria MetaADEDB
Aortic Disorder MetaADEDB
Aortic Dissection MetaADEDB
Aphonia MetaADEDB
Apoplexy MetaADEDB
Appetite Disorder MetaADEDB
Arrhythmia ADReCS
Arterial Bypass Operation MetaADEDB
Arterial Disorder ADReCS
Arterial Stenosis MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Asterixis MetaADEDB
Asthenia MetaADEDB
Asthma MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Auricular Swelling MetaADEDB
Av Dissociation MetaADEDB
Back Pain ADReCS
Belching MetaADEDB
Bile Duct Obstruction MetaADEDB
Biopsy MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Neoplasm MetaADEDB
Bleeding Gums MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Erythropoietin Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood Immunoglobulin A Increased MetaADEDB
Blood Ketone Body MetaADEDB
Body Temperature MetaADEDB
Bone Debridement MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Fibrosis MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer Male MetaADEDB
Breast Cancer Stage I MetaADEDB
Bronchial Disorder MetaADEDB
Bronchitis ADReCS
Bundle Branch Block Left MetaADEDB
Burkitt Lymphoma MetaADEDB
Bursitis MetaADEDB
Cachectic MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Ischemia MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Cardiovascular Disorder ADReCS
Carotid Artery Disease MetaADEDB
Cataract Nuclear MetaADEDB
Catheter Placement MetaADEDB
Catheter Thrombosis MetaADEDB
Caustic Injury MetaADEDB
Cellulitis MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebral Atrophy MetaADEDB
Cervical Cord Compression MetaADEDB
Chest Pain ADReCS
Cholangitis Acute MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cirrhosis MetaADEDB
Clonus MetaADEDB
Clostridial Infection MetaADEDB
Clotting MetaADEDB
Coeliac Disease MetaADEDB
Colitis MetaADEDB
Colon Spastic MetaADEDB
Compression Fracture MetaADEDB
Concomitant Disease Progression MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Coombs Positive Haemolytic Anaemia MetaADEDB
Cor Pulmonale MetaADEDB
Coronary Angioplasty MetaADEDB
Coronary Artery Disease ADReCS
Coronary Artery Stenosis MetaADEDB
Coronary Artery Surgery MetaADEDB
Crackles Lung MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Creatinine Renal Clearance Increased MetaADEDB
Cushing Syndrome MetaADEDB
Cutaneous Ulcer MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Death ADReCS
Decubitus Ulcer MetaADEDB
Deep Vein Thromboses MetaADEDB
Dehydration MetaADEDB
Dementia Alzheimer Type MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Dermabrasion MetaADEDB
Dermatitides MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Detached Retina MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Foot MetaADEDB
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinal Oedema MetaADEDB
Diabetic Retinopathy MetaADEDB
Diabetic Vascular Disorder MetaADEDB
Diaphragmatic Hernia MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Disorder Lung MetaADEDB
Disseminated Cytomegaloviral Infection MetaADEDB
Dizziness MetaADEDB
Dizziness Exertional MetaADEDB
Drop Attacks MetaADEDB
Drowsiness MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Interaction MetaADEDB
Dry Skin MetaADEDB
Dyslipidaemia MetaADEDB
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Early Satiety MetaADEDB
Ecchymoses MetaADEDB
Economic Problem MetaADEDB
Eczema MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Abnormal ADReCS
Electrocardiogram Ambulatory Abnormal MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Electrolyte Disorder MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Emotional Disorder MetaADEDB
Encephalitis Cytomegalovirus MetaADEDB
Encephalopathy MetaADEDB
Endocrine Neoplasm Malignant MetaADEDB
Energy Increased MetaADEDB
Enteritis MetaADEDB
Epistaxis MetaADEDB
Erysipelas MetaADEDB
Erythema PROTECT
Erythremia MetaADEDB
Escherichia Bacteraemia MetaADEDB
Essential Tremor MetaADEDB
Excessive Granulation Tissue MetaADEDB
External Ear Infection MetaADEDB
Extremity Necrosis MetaADEDB
Facial Palsy MetaADEDB
Faecaloma MetaADEDB
Faeces Discoloured MetaADEDB
Familial Hypercholesterolemia MetaADEDB
Family Stress MetaADEDB
Fatty Liver MetaADEDB
Fear Of Death MetaADEDB
Femoral Pulse Decreased MetaADEDB
Fibrous Histiocytoma MetaADEDB
Fixed Eruption MetaADEDB
Flatulence MetaADEDB
Floppy Iris Syndrome MetaADEDB
Food Allergy MetaADEDB
Food Aversion MetaADEDB
Food Craving MetaADEDB
Furuncle MetaADEDB
Gastric Infection MetaADEDB
Gastric Polyps MetaADEDB
Gastric Ulcer Helicobacter MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastroduodenitis MetaADEDB
Gastroenteritis MetaADEDB
Gastroenteritis Rotavirus MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Sounds Abnormal MetaADEDB
General Physical Health Deterioration MetaADEDB
Genital Herpes MetaADEDB
Glutamate Dehydrogenase Increased MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Granulocytosis MetaADEDB
Haemolytic Anaemia ADReCS
Haemorrhagic Transformation Stroke MetaADEDB
Hantaviral Infection MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Hemiparesis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis Alcoholic MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatocellular Injury MetaADEDB
Herpes Zoster MetaADEDB
Humerus Fracture MetaADEDB
Hyperammonaemia MetaADEDB
Hypercapnia MetaADEDB
Hypercreatininaemia MetaADEDB
Hypergammaglobulinaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis MetaADEDB
Hyperinsulinaemia MetaADEDB
Hyperlipaemia MetaADEDB
Hypermetropia MetaADEDB
Hyperpigmentation MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive Cardiomyopathy MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hyperviscosity Syndrome MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypoglycaemia ADReCS
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Coma PROTECT
Hypoglycaemic Unconsciousness PROTECT
Hypokalaemia MetaADEDB
Hypokinesia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypoprothrombinaemia MetaADEDB
Hypoxia MetaADEDB
Idiopathic Urticaria MetaADEDB
Immunosuppressant Drug Level Decreased MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impingement Syndrome MetaADEDB
Inadequate Diet MetaADEDB
Increased Appetite MetaADEDB
Infarction ADReCS
Infection ADReCS
Inflammatory Bowel Disease MetaADEDB
Injection Site Dermatitis MetaADEDB
Injection Site Paraesthesia MetaADEDB
Injection Site Urticaria MetaADEDB
Intention Tremor MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intestinal Ulcer MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intracardiac Thrombus MetaADEDB
Ischaemia ADReCS
Ischaemic Cardiomyopathy MetaADEDB
Jaundice ADReCS
Joint Sprain MetaADEDB
Kidney Failure MetaADEDB
Laceration MetaADEDB
Large Intestine Perforation MetaADEDB
Lethargy MetaADEDB
Leukaemoid Reaction MetaADEDB
Leukopenia ADReCS
Lichen Planus MetaADEDB
Lichenoid Keratosis MetaADEDB
Lipase MetaADEDB
Localised Oedema MetaADEDB
Locked-In Syndrome MetaADEDB
Loss Of Weight MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lupus Hepatitis MetaADEDB
Lymphangiectasia Intestinal MetaADEDB
Lymphocytes Decreased MetaADEDB
Macular Oedema MetaADEDB
Macular Pseudohole MetaADEDB
Meningeal Neoplasm MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Liver MetaADEDB
Metastatic Malignant Melanoma MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Micturition Urgency MetaADEDB
Mixed Liver Injury MetaADEDB
Monoclonal Immunoglobulin Present MetaADEDB
Mood Altered MetaADEDB
Mucosal Ulceration MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Myelocytosis MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Nail Tinea MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
No Match PROTECT
Nodule On Extremity MetaADEDB
Nodule Skin MetaADEDB
Normal Pressure Hydrocephalus SIDER
Nutritional Condition Abnormal MetaADEDB
Obstructive Airways Disorder MetaADEDB
Ocular Icterus MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oliguria MetaADEDB
Orthopnea MetaADEDB
Orthostatic Hypertension MetaADEDB
Osteolysis MetaADEDB
Otitis Externa Fungal MetaADEDB
Pain ADReCS
Palatal Oedema MetaADEDB
Palpitations ADReCS
Pancreatic Cancer MetaADEDB
Pancreatic Carcinoma Metastatic MetaADEDB
Pancreatitis ADReCS
Paraesthesia ADReCS
Parakeratosis MetaADEDB
Paresis Cranial Nerve MetaADEDB
Pelvic Abscess MetaADEDB
Pericarditis Uraemic MetaADEDB
Peritoneal Effusion MetaADEDB
Photodermatosis MetaADEDB
Pitting Oedema MetaADEDB
Pleural Disorder MetaADEDB
Pneumoperitoneum MetaADEDB
Pollakiuria MetaADEDB
Polysubstance Dependence MetaADEDB
Postoperative Wound Infection MetaADEDB
Potentiating Drug Interaction MetaADEDB
Pre-Existing Disease MetaADEDB
Product Counterfeit MetaADEDB
Progressive Supranuclear Palsy MetaADEDB
Prostate Infection MetaADEDB
Protein-Losing Gastroenteropathy MetaADEDB
Prothrombin Time MetaADEDB
Pruritus PROTECT
Pseudomonal Bacteraemia MetaADEDB
Psoriasis MetaADEDB
Pulmonary Arterial Hypertension MetaADEDB
Puncture Site Haemorrhage MetaADEDB
Purulent Discharge MetaADEDB
Radicular Syndrome MetaADEDB
Rales MetaADEDB
Rash PROTECT
Reflux Esophagitis MetaADEDB
Renal Embolism MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Oncocytoma MetaADEDB
Respiratory Tract Congestion MetaADEDB
Reversible Ischaemic Neurological Deficit MetaADEDB
Rhagades MetaADEDB
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Rib Fracture MetaADEDB
Schizophrenia MetaADEDB
Sepsis Syndrome MetaADEDB
Sinus Bradycardia MetaADEDB
Sinusitis ADReCS
Skin Hypertrophy MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Skin Plaque MetaADEDB
Skin Tightness MetaADEDB
Sleep Apnea MetaADEDB
Social Avoidant Behaviour MetaADEDB
Social Problem MetaADEDB
Somogyi Phenomenon MetaADEDB
Sopor MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress Cardiomyopathy MetaADEDB
Sudden Death MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Thoracic Vertebral Fracture MetaADEDB
Throat Cancer MetaADEDB
Throat Tightness MetaADEDB
Thrombocytopenia ADReCS
Thyroid Cyst MetaADEDB
Tinea MetaADEDB
Toe Amputation MetaADEDB
Tongue Biting MetaADEDB
Tongue Disorder MetaADEDB
Tooth Disorder ADReCS
Tooth Fracture MetaADEDB
Toxic Skin Eruption MetaADEDB
Transaminases Increased MetaADEDB
Transient Ischaemic Attack MetaADEDB
Ulcer MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urethral Haemorrhage MetaADEDB
Urinary Tract Infection ADReCS
Urticaria PROTECT
Vaginal Mycosis MetaADEDB
Vascular Graft Occlusion MetaADEDB
Vasculitis PROTECT
Ventricular Fibrillation MetaADEDB
Viith Nerve Paralysis MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Weight Loss Poor MetaADEDB
White Blood Cell Count Abnormal MetaADEDB
Xerosis MetaADEDB

InAADR: Drug-Protein-ADRs database