InAADR

Drug Information

Drug Name: Ranolazine (142387-99-3)
PubChem ID: 56959
SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O
InchiKey: XKLMZUWKNUAPSZ-UHFFFAOYSA-N
Therapeutic Category: Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 427.545
LogP: 2.30804
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 74.27

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Pain ADReCS
Acute Coronary Syndrome ADReCS
Amnesia PROTECT
Angioedema ADReCS
Angiopathy ADReCS
Anorexia ADReCS
Anxiety PROTECT
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Asthenia ADReCS
Blood Creatinine Increased ADReCS
Blood Urea Increased ADReCS
Bradycardia ADReCS
Cardiac Disorder ADReCS
Chromaturia ADReCS
Cold Sweat PROTECT
Confusional State ADReCS
Constipation ADReCS
Coordination Abnormal PROTECT
Cough PROTECT
Creatinine Increased SIDER
Creatinine Renal Clearance Decreased PROTECT
Decreased Appetite ADReCS
Dehydration PROTECT
Depressed Level Of Consciousness PROTECT
Dermatitis ADReCS
Dermatitis Allergic PROTECT
Diabetes Mellitus ADReCS
Diplopia PROTECT
Disease Progression ADReCS
Disorientation PROTECT
Dizziness ADReCS
Dizziness Postural PROTECT
Dry Mouth ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysuria PROTECT
Electrocardiogram Qt Prolonged PROTECT
Eosinophilia ADReCS
Epistaxis PROTECT
Erectile Dysfunction PROTECT
Erosive Duodenitis PROTECT
Eye Disorder SIDER
Fatigue PROTECT
Feeling Abnormal ADReCS
Fibrosis ADReCS
Flatulence PROTECT
Gait Disturbance PROTECT
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Haematuria ADReCS
Hallucination ADReCS
Headache ADReCS
Hearing Impaired PROTECT
Hepatic Enzyme Increased PROTECT
Hot Flush PROTECT
Hyperhidrosis ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Oral PROTECT
Hypotension ADReCS
Insomnia PROTECT
Joint Swelling PROTECT
Lethargy PROTECT
Leukopenia ADReCS
Loss Of Consciousness ADReCS
Mediastinal Disorder SIDER
Mental Disorder SIDER
Muscle Spasms PROTECT
Nausea ADReCS
Nephropathy Toxic ADReCS
Nervous System Disorder SIDER
Oedema ADReCS
Oedema Peripheral ADReCS
Orthostatic Hypotension ADReCS
Pain ADReCS
Pain In Extremity PROTECT
Palpitations ADReCS
Pancreatitis PROTECT
Pancytopenia ADReCS
Paraesthesia ADReCS
Parosmia PROTECT
Peripheral Coldness PROTECT
Platelet Count Increased PROTECT
Pruritus ADReCS
Pulmonary Fibrosis ADReCS
Rash ADReCS
Renal Failure ADReCS
Renal Failure Acute PROTECT
Renal Tubular Disorder ADReCS
Shock ADReCS
Somnolence PROTECT
Syncope ADReCS
Throat Tightness PROTECT
Thrombocytopenia ADReCS
Tinnitus ADReCS
Tremor ADReCS
Urea Increased SIDER
Urethral Disorder SIDER
Urinary Retention PROTECT
Urinary Tract Disorder SIDER
Urticaria PROTECT
Vertical Talus SIDER
Vertigo ADReCS
Vision Blurred ADReCS
Visual Impairment PROTECT
Vomiting ADReCS
Weight Decreased PROTECT
White Blood Cell Count Increased PROTECT

InAADR: Drug-Protein-ADRs database