InAADR

Drug Information

Drug Name: Pentazocine (359-83-1)
PubChem ID: 12259685
SMILES: C[C@@H]1[C@@H]2CC3=C([C@]1(CCN2CC=C(C)C)C)C=C(C=C3)O
InchiKey: VOKSWYLNZZRQPF-CCKFTAQKSA-N
Therapeutic Category: Adjuvants, Analgesics, Central Nervous System Agents, Central Nervous System Depressants, Narcotic Antagonists, Narcotics, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 285.431
LogP: 3.8826
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 23.47

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Acetylsalicylic acid (50-78-2) Renal Papillary Necrosis Antagonistic Pentazocine-induced reduction in blood flow through the kidney potentiated the adverse effects of chronic aspirin use Renal papillary necrosis caused by long-term ingestion of pentazocine and aspirin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cavity Drainage MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Dreams ADReCS
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accident At Work MetaADEDB
Acidosis Respiratory MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Acute Graft Versus Host Disease In Intestine MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Cortex Necrosis MetaADEDB
Adrenal Disorder MetaADEDB
Adverse Event MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Airway Obstruction MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Consumption MetaADEDB
Allergic Reaction ADReCS
Amnesia MetaADEDB
Amyloidosis MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Aneurysm MetaADEDB
Angiitis MetaADEDB
Angina MetaADEDB
Anorexia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anxiety MetaADEDB
Anxiety Disorder MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Dissection MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Arachnoiditis MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriospasm Coronary MetaADEDB
Arteriovenous Fistula MetaADEDB
Arthralgia MetaADEDB
Arthritis MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Atelectasis MetaADEDB
Atrophy MetaADEDB
Attempted Suicide MetaADEDB
Automatism MetaADEDB
Back Pain MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Cell Carcinoma MetaADEDB
Bile Duct Obstruction MetaADEDB
Bipolar Disorder MetaADEDB
Bleb MetaADEDB
Bleeding Gums MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Brain Barrier Defect MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Parathyroid Hormone Increased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Test Abnormal MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia MetaADEDB
Brain Abscess MetaADEDB
Brain Edema MetaADEDB
Brain Oedema MetaADEDB
Bruise MetaADEDB
Bulbar Palsy MetaADEDB
Bundle Branch Block Right MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calcinosis MetaADEDB
Cancer MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Massage MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiovascular Disorder MetaADEDB
Cardiovascular Insufficiency ADReCS
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Catheter Related Complication MetaADEDB
Catheterisation Cardiac MetaADEDB
Central Nervous System Diseases MetaADEDB
Central Nervous System Lymphoma MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chest Pain MetaADEDB
Chills ADReCS
Cholecystitis MetaADEDB
Cholecystitis Chronic MetaADEDB
Cholinergic Syndrome MetaADEDB
Coma MetaADEDB
Confusion MetaADEDB
Confusional State ADReCS
Constipated MetaADEDB
Constipation ADReCS
Contracture MetaADEDB
Coronary Angioplasty MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Artery Restenosis MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Cryptogenic Organising Pneumonia MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyanosis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Decreased Activity MetaADEDB
Delayed Emergence From Anesthesia MetaADEDB
Denervation Atrophy MetaADEDB
Dependence MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depression ADReCS
Depressive Disorder MetaADEDB
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Diaphragmatic Disorder MetaADEDB
Diarrhoea ADReCS
Diffuse Alveolar Damage MetaADEDB
Diplopia ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disease Recurrence MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drug Dependence ADReCS
Drug Screen Positive MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer Perforation MetaADEDB
Dysgeusia ADReCS
Dysphonia MetaADEDB
Dyspnoea ADReCS
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Echinococciasis MetaADEDB
Electrocardiogram Change MetaADEDB
Electrocardiogram P Wave Abnormal MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Electrolyte Disorder MetaADEDB
Embolism Pulmonary MetaADEDB
Endocarditis Bacterial MetaADEDB
Enteritis Infectious MetaADEDB
Enterobacter Sepsis MetaADEDB
Eosinophilia ADReCS
Epidermal Necrolysis Toxic MetaADEDB
Epilepsy Tonic-Clonic MetaADEDB
Euphoric Mood ADReCS
Excess Potassium MetaADEDB
Excitement SIDER
Exercise Electrocardiogram Abnormal MetaADEDB
Exercise Test Abnormal MetaADEDB
Extrasystoles Ventricular MetaADEDB
Face Oedema ADReCS
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Fetal Growth Retardation MetaADEDB
Fibrosis MetaADEDB
Flushing ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Dilatation MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastritis Bacterial MetaADEDB
Gastroenteritis Bacillus MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Infection MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Gingival Erythema MetaADEDB
Glomerulonephritis Membranoproliferative MetaADEDB
Haematochezia MetaADEDB
Haemodialysis MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Haemothorax MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Attack MetaADEDB
Heart Valve Replacement MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis Fulminant MetaADEDB
Herpes Simplex MetaADEDB
Herpes Zoster Disseminated MetaADEDB
Herpes Zoster Infection Neurological MetaADEDB
Hip Contracture MetaADEDB
Hyperammonaemia MetaADEDB
Hyperamylasaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertension Pulmonary MetaADEDB
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypokalaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypothyroid MetaADEDB
Hypoxia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Iatrogenic Disease MetaADEDB
Ild MetaADEDB
Impaired Gastric Emptying MetaADEDB
Induration ADReCS
Infection MetaADEDB
Injection Site Discolouration MetaADEDB
Injection Site Pain ADReCS
Injection Site Ulcer MetaADEDB
Insomnia ADReCS
Intercostal Neuralgia MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intracranial Hemorrhages MetaADEDB
Intracranial Hypertension MetaADEDB
Irritability ADReCS
Joint Abscess MetaADEDB
Kidney Failure MetaADEDB
Kidney Papillary Necrosis MetaADEDB
Knee Operation MetaADEDB
Labor Pain MetaADEDB
Large Intestinal Ulcer MetaADEDB
Laryngeal Dyspnoea MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Life Support MetaADEDB
Lightheadedness SIDER
Lordosis MetaADEDB
Loss Of Consciousness ADReCS
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm MetaADEDB
Lyell MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocytes Decreased MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Mental Disorders MetaADEDB
Miliary Pneumonia MetaADEDB
Miosis ADReCS
Mononeuropathies MetaADEDB
Morphoea ADReCS
Mouth Ulcer MetaADEDB
Mucous Membrane Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Injury MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Muscular Atrophy MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Myocardial Infarction MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Neonatal Abstinence Syndrome MetaADEDB
Neonatal Respiratory Failure MetaADEDB
Nephritis Interstitial MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Compression Syndromes MetaADEDB
Neumonia MetaADEDB
Neurologic Manifestations MetaADEDB
Neuromuscular Diseases MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nodule ADReCS
Nystagmus ADReCS
Obstructive Airways Disorder MetaADEDB
Ocular Motility Disorders MetaADEDB
Oedema ADReCS
Oliguria MetaADEDB
Opioid-Related Disorders MetaADEDB
Oral Herpes MetaADEDB
Osteoarthritis Spine MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Oxygen Supplementation MetaADEDB
Pain MetaADEDB
Pain Postoperative MetaADEDB
Pallor MetaADEDB
Pancreatic Necrosis MetaADEDB
Pancytopenia MetaADEDB
Paraesthesia ADReCS
Paresthesia MetaADEDB
Pericarditis MetaADEDB
Peritoneal Adhesions MetaADEDB
Petechia MetaADEDB
Phlebothrombosis MetaADEDB
Pigmentation Disorders MetaADEDB
Platelet Count MetaADEDB
Pleural Adhesion MetaADEDB
Pleural Effusion MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pollakiuria MetaADEDB
Polymyositis MetaADEDB
Polyradiculopathy MetaADEDB
Polyuria MetaADEDB
Post Procedural Bile Leak MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Premature Separation Of Placenta MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Procedural Complication MetaADEDB
Pruritus ADReCS
Psychoses Substance-Induced MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Bulla MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Embolism MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Infarction MetaADEDB
Radial Neuropathy MetaADEDB
Radicular Pain MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Impairment MetaADEDB
Renal Surgery MetaADEDB
Respiratory Depression ADReCS
Respiratory Disorder MetaADEDB
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Rhabdomyolysis MetaADEDB
Sciatic Neuropathy MetaADEDB
Scleroderma Limited MetaADEDB
Scleroderma Localized MetaADEDB
Sclerosis MetaADEDB
Sedation ADReCS
Seizures MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Shock ADReCS
Shoulder Dislocation MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinus Disorder MetaADEDB
Skin Disorder ADReCS
Skin Exfoliation ADReCS
Skin Ulcer MetaADEDB
Skin Ulcer Haemorrhage MetaADEDB
Snoring MetaADEDB
Soft Tissue Disorder ADReCS
Spondylosis MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Staphylococcal Infection MetaADEDB
Stent Placement MetaADEDB
Stroke MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Substance Abuse Intravenous MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Substance-Related Disorders MetaADEDB
Sudden Death MetaADEDB
Sweating Increased SIDER
Syncope ADReCS
Tachycardia ADReCS
Taste Alteration ADReCS
Thrombotic Microangiopathy MetaADEDB
Tinnitus ADReCS
Toxic Encephalopathy MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Tremor ADReCS
Tremor Muscle SIDER
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Uremia MetaADEDB
Urinary Retention ADReCS
Urine Abnormality MetaADEDB
Uterine Contractions Abnormal ADReCS
Valvuloplasty Cardiac MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vertigo MetaADEDB
Viral Dna Test Positive MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Vulval Oedema MetaADEDB
Weakness SIDER
White Blood Cell Count Decreased ADReCS
Wound Infection Staphylococcal MetaADEDB
Xerostomia MetaADEDB

InAADR: Drug-Protein-ADRs database