InAADR

Drug Information

Drug Name: Papaverine (58-74-2)
PubChem ID: 4680
SMILES: COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC
InchiKey: XQYZDYMELSJDRZ-UHFFFAOYSA-N
Therapeutic Category: Cardiovascular Agents, Enzyme Inhibitors, Phosphodiesterase Inhibitors, Urological Agents, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 339.391
LogP: 3.86
Ring Count: 3
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 49.81

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Levodopa (59-92-7) Parkinsonism Antagonistic Not understood Antagonism of levodopa by papaverine

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Anorexia ADReCS
Aphasia MetaADEDB
Arrhythmias Cardiac MetaADEDB
Arterial Occlusive Diseases MetaADEDB
Atrioventricular Block MetaADEDB
Blindness MetaADEDB
Blood Pressure Increased ADReCS
Bradycardia MetaADEDB
Catalepsy MetaADEDB
Cerebral Arterial Diseases MetaADEDB
Chest Pain MetaADEDB
Choroid Diseases MetaADEDB
Coma MetaADEDB
Constipation ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Dizziness MetaADEDB
Dyskinesia Drug-Induced MetaADEDB
Dyspareunia MetaADEDB
Edema MetaADEDB
Erectile Dysfunction MetaADEDB
Exophthalmos MetaADEDB
Facial Nerve Diseases MetaADEDB
Facial Paralysis MetaADEDB
Feeling Abnormal ADReCS
Fibrosis MetaADEDB
Flushing ADReCS
Headache ADReCS
Hearing Loss Sensorineural MetaADEDB
Heart Rate Increased ADReCS
Hematoma MetaADEDB
Hemiplegia MetaADEDB
Hepatic Cirrhosis ADReCS
Hepatitis ADReCS
Hepatitis Chronic MetaADEDB
Hyperemia MetaADEDB
Hyperhidrosis ADReCS
Hypotension MetaADEDB
Ill-Defined Disorder ADReCS
Impotence Vasculogenic MetaADEDB
Infarction MetaADEDB
Intracranial Embolism MetaADEDB
Intracranial Hypertension MetaADEDB
Jaundice MetaADEDB
Liver Cirrhosis MetaADEDB
Long Qt Syndrome MetaADEDB
Malaise ADReCS
Muscle Weakness MetaADEDB
Mydriasis MetaADEDB
Nausea ADReCS
Neurologic Manifestations MetaADEDB
Paresis MetaADEDB
Penile Induration MetaADEDB
Postoperative Complications MetaADEDB
Priapism MetaADEDB
Rash ADReCS
Respiration Abnormal ADReCS
Respiratory Insufficiency MetaADEDB
Sedation ADReCS
Sinus Arrest Cardiac MetaADEDB
Spasm MetaADEDB
Sweating SIDER
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Thrombosis MetaADEDB
Torsades De Pointes MetaADEDB
Tranquillisation Excessive SIDER
Vasospasm Intracranial MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertigo ADReCS
Vestibulocochlear Nerve Diseases MetaADEDB

InAADR: Drug-Protein-ADRs database