InAADR

Drug Information

Drug Name: Ondansetron (99614-02-5)
PubChem ID: 4595
SMILES: CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
InchiKey: FELGMEQIXOGIFQ-UHFFFAOYSA-N
Therapeutic Category: Anti-Anxiety Agents, Antiemetics, Antipruritics, Antipsychotic Agents, Autonomic Agents, Central Nervous System Agents, Central Nervous System Depressants, Dermatologic Agents, Gastrointestinal Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Psychotropic Drugs, Serotonin Agents, Serotonin Antagonists, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 293.37
LogP: 3.12852
Ring Count: 3
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 39.82

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abdominal Rigidity MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abuse MetaADEDB
Accommodation Disorder ADReCS
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Psychosis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenitis MetaADEDB
Adenocarcinoma MetaADEDB
Adenopathy MetaADEDB
Adhesiolysis MetaADEDB
Adnexitis MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Akathisia ADReCS
Alcoholism MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Vasculitis MetaADEDB
Alpha Haemolytic Streptococcal Infection MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anaemia Of Chronic Disease MetaADEDB
Anaesthesia MetaADEDB
Anaesthetic Complication MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Angina Pectoris ADReCS
Angioedema ADReCS
Anorexia MetaADEDB
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphagia MetaADEDB
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Arthrodesis MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block ADReCS
Atrioventricular Block Second Degree ADReCS
Bacillus Infection MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Ganglia Diseases MetaADEDB
Bence Jones Protein Urine MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Bone Marrow Abnormal MetaADEDB
Black Stools MetaADEDB
Bladder Perforation MetaADEDB
Blepharospasm MetaADEDB
Blindness ADReCS
Blindness Transient ADReCS
Blister ADReCS
Block Heart SIDER
Blood Bicarbonate Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Homocysteine MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urine Present MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Diseases MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Fibrosis MetaADEDB
Bone Spur MetaADEDB
Bradycardia ADReCS
Brain Damage MetaADEDB
Breast Cellulitis MetaADEDB
Breast Neoplasms MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchial Secretion Retention MetaADEDB
Bronchospasm ADReCS
Bundle Branch Block MetaADEDB
Bundle Branch Block Right MetaADEDB
Burning Sensation Mucosal MetaADEDB
Caecitis MetaADEDB
Caesarean Section MetaADEDB
Calcinosis MetaADEDB
Calculus Ureteric MetaADEDB
Candida Infection MetaADEDB
Capillary Leak Syndrome MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Arrest ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardio-Respiratory Arrest ADReCS
Cardiogenic Shock MetaADEDB
Cardiotoxicity MetaADEDB
Cardiovascular Disorder ADReCS
Catatonia MetaADEDB
Catheter Bacteraemia MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Site Pain MetaADEDB
Cd8 Lymphocytes Decreased MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Chapped Lips MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Chorea MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Respiratory Failure MetaADEDB
Clonus MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cognition Disorders MetaADEDB
Color Blindness MetaADEDB
Confabulation MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Connective Tissue Disorder SIDER
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Cyanosis MetaADEDB
Cyst MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Oesophagitis MetaADEDB
Deafness Unilateral MetaADEDB
Death ADReCS
Debridement MetaADEDB
Decreased Activity MetaADEDB
Decubitus Ulcer MetaADEDB
Dehydration MetaADEDB
Delirium MetaADEDB
Dental Pain MetaADEDB
Depressive Disorder MetaADEDB
Depressive Disorder Major MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Detached Retina MetaADEDB
Device Related Infection MetaADEDB
Diabetes Insipidus Nephrogenic MetaADEDB
Diabetic Ketoacidosis MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disease Progression MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Retinal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticular Perforation MetaADEDB
Diverticulosis MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Therapy MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dysphonia MetaADEDB
Dyspnoea ADReCS
Dystonia ADReCS
Dystonic Reaction SIDER
Dysuria ADReCS
Effusion MetaADEDB
Electrocardiogram Change ADReCS
Electrocardiogram Qt Prolonged ADReCS
Electrocardiogram St Segment SIDER
Electrocardiogram St Segment Abnormal MetaADEDB
Electrocardiogram St Segment Depression ADReCS
Electromechanical Dissociation MetaADEDB
Elevated Triglycerides MetaADEDB
Embolism Pulmonary MetaADEDB
Encephalopathy MetaADEDB
Enteritis MetaADEDB
Enteritis Infectious MetaADEDB
Enterobacter Pneumonia MetaADEDB
Enterococcal Bacteraemia MetaADEDB
Epistaxis MetaADEDB
Erosive Gastritis MetaADEDB
Erythema ADReCS
Escherichia Sepsis MetaADEDB
Extrapyramidal Disorder ADReCS
Extremity Necrosis MetaADEDB
Eye Disorder SIDER
Eye Muscle Operation MetaADEDB
Fasciotomy MetaADEDB
Fatigue ADReCS
Febrile Neutropenia MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold ADReCS
Feeling Lonely ADReCS
Female Genital Tract Fistula MetaADEDB
Fib MetaADEDB
Floaters MetaADEDB
Fluid Overload MetaADEDB
Flushing ADReCS
Foetal Growth Retardation MetaADEDB
Foetor Hepaticus ADReCS
Fractured Pelvis Nos MetaADEDB
Fungal Disease MetaADEDB
Gall Bladder MetaADEDB
Gangrene MetaADEDB
Gastric Cancer MetaADEDB
Gastric Disorder ADReCS
Gastric Ulcer MetaADEDB
Gastritis MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis Cryptosporidial MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrointestinal Stromal Tumour MetaADEDB
Gaze Palsy MetaADEDB
General Physical Health Deterioration MetaADEDB
Genital Disorder Female SIDER
Globulinuria MetaADEDB
Grand Mal Convulsion ADReCS
Grip Strength MetaADEDB
Gynaecological Examination Abnormal ADReCS
Haematemesis MetaADEDB
Haemorrhoids MetaADEDB
Hair Texture Abnormal MetaADEDB
Headache ADReCS
Heart Block MetaADEDB
Heart Rate Increased MetaADEDB
Heart-Lung Transplant Rejection MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme Abnormal ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Necrosis ADReCS
Hepatitis ADReCS
Hepatobiliary Disease SIDER
Hepatocellular Injury ADReCS
Herpes Simplex MetaADEDB
Herpes Zoster MetaADEDB
Hiccough MetaADEDB
Hiccups ADReCS
Hodgkin Disease MetaADEDB
Humerus Fracture MetaADEDB
Hydrocephalus MetaADEDB
Hydronephrosis MetaADEDB
Hyperaesthesia MetaADEDB
Hyperalgesia MetaADEDB
Hyperalimentation MetaADEDB
Hyperhidrosis ADReCS
Hyperkeratosis MetaADEDB
Hyperkinesis MetaADEDB
Hypermagnesaemia MetaADEDB
Hyperosmolar State MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperpigmentation MetaADEDB
Hyperreflexia MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypoaesthesia MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypokalaemia ADReCS
Hypokalemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypophagia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypotension ADReCS
Hypothyroid MetaADEDB
Hypoxia ADReCS
Ild MetaADEDB
Ileitis MetaADEDB
Ill-Defined Disorder ADReCS
Immune Reconstitution Syndrome MetaADEDB
Immune System Disorder SIDER
Immunosuppression MetaADEDB
Implant Site Reaction MetaADEDB
Inappropriate Schedule Of Drug Administration MetaADEDB
Incisional Hernia Obstructive MetaADEDB
Infarction ADReCS
Infection Urinary Tract MetaADEDB
Infusion Related Reaction MetaADEDB
Infusion Site Swelling MetaADEDB
Ingrowing Nail MetaADEDB
Injection Site Burning ADReCS
Injection Site Reaction ADReCS
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intestinal Fistula MetaADEDB
Intestinal Obstruction MetaADEDB
Intestinal Perforation MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemia ADReCS
Ischaemic Cerebral Infarction MetaADEDB
Ischaemic Hepatitis MetaADEDB
Jaundice ADReCS
Jaw Disorder MetaADEDB
Joint Effusion MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Failure MetaADEDB
Labelled Drug-Drug Interaction Medication Error MetaADEDB
Laryngeal Oedema ADReCS
Laryngospasm ADReCS
Learning Disorders MetaADEDB
Legal Problem MetaADEDB
Lethargy ADReCS
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Lip Pain MetaADEDB
Lipase MetaADEDB
Liver Disorder ADReCS
Local Reaction SIDER
Local Swelling MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Lower Extremity Mass MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lung Infiltration MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Transformation Test Positive ADReCS
Lymphoproliferative Disorder MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Masked Facies MetaADEDB
Mediastinal Disorder SIDER
Memory Disorders MetaADEDB
Meningitides MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Artery Thrombosis MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Ovary MetaADEDB
Metastatic Renal Cell Carcinoma MetaADEDB
Metatarsalgia MetaADEDB
Migraine Disorders MetaADEDB
Mitral Valve Calcification MetaADEDB
Mitral Valve Prolapse MetaADEDB
Mouth Ulcer MetaADEDB
Movement Disorder ADReCS
Mucosal Inflammation MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Mass MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Swelling MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myocardial Ischemia MetaADEDB
Nausea MetaADEDB
Necrolysis Epidermal SIDER
Necrosis ADReCS
Neonatal Respiratory Distress Syndrome MetaADEDB
Neoplasm Progression MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrolithiasis MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neuroectodermal Tumors MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutropenic Infection MetaADEDB
Nystagmus MetaADEDB
Obstructive Airways Disorder MetaADEDB
Obstructive Uropathy MetaADEDB
Occult Blood Positive MetaADEDB
Ocular Motility Disorders MetaADEDB
Oculogyric Crisis ADReCS
Oedema ADReCS
Oedema Mouth MetaADEDB
Off Label Use MetaADEDB
Oophorectomy MetaADEDB
Opisthotonus ADReCS
Opportunistic Infection MetaADEDB
Optic Neuritis MetaADEDB
Oral Intake Reduced MetaADEDB
Orofacial Dyskinesia ADReCS
Oropharyngeal Pain MetaADEDB
Osteoarthritis MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Pain Postoperative MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Palsies MetaADEDB
Paraesthesia ADReCS
Paraesthesia Oral MetaADEDB
Pericardial Effusion MetaADEDB
Pericarditis MetaADEDB
Peritonitis MetaADEDB
Peritonsillitis MetaADEDB
Phlebothrombosis MetaADEDB
Platelet Count MetaADEDB
Platelet Transfusion MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Klebsiella MetaADEDB
Pneumonia Respiratory Syncytial Viral MetaADEDB
Pneumothorax MetaADEDB
Pneumothorax Traumatic MetaADEDB
Polyuria MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Postoperative Wound Complication MetaADEDB
Postoperative Wound Infection MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Procedural Nausea MetaADEDB
Procedural Pain MetaADEDB
Procedural Vomiting MetaADEDB
Prostatitis MetaADEDB
Pruritus ADReCS
Pseudomonal Sepsis MetaADEDB
Psychomotor Agitation MetaADEDB
Psychoses Substance-Induced MetaADEDB
Pulmonary Vascular Disorder MetaADEDB
Pyrexia ADReCS
Quality Of Life Decreased MetaADEDB
Radius Fracture MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Redness SIDER
Renal Atrophy MetaADEDB
Renal Cyst MetaADEDB
Renal Infarct MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Scar MetaADEDB
Seborrhoeic Keratosis MetaADEDB
Sedation ADReCS
Seizures SIDER
Septic Shock MetaADEDB
Serratia Infection MetaADEDB
Shivering ADReCS
Shock ADReCS
Sinusitis MetaADEDB
Skin Swelling MetaADEDB
Skin Test Positive MetaADEDB
Sleep Attacks MetaADEDB
Social Problem MetaADEDB
Somnolence ADReCS
Spasm MetaADEDB
Staphylococcal Infection MetaADEDB
Stereotypic Movement Disorder MetaADEDB
Stridor ADReCS
Subacute Endocarditis MetaADEDB
Subcutaneous Nodule MetaADEDB
Subendocardial Ischaemia MetaADEDB
Subileus MetaADEDB
Submandibular Mass MetaADEDB
Substance Abuse MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Supraventricular Tachycardia ADReCS
Syncope ADReCS
Syncope Vasovagal MetaADEDB
Systemic Candida MetaADEDB
Tachycardia ADReCS
Tachycardia Supraventricular MetaADEDB
Tachycardia Ventricular MetaADEDB
Tonic-Clonic Seizures SIDER
Tooth Discolouration MetaADEDB
Torsade De Pointes ADReCS
Toxic Epidermal Necrolysis ADReCS
Transaminases Increased ADReCS
Tremor ADReCS
Troponin I Increased MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Tumour Necrosis MetaADEDB
Tumour Perforation MetaADEDB
Type I Hypersensitivity ADReCS
Unresponsive To Stimuli MetaADEDB
Urinary Retention ADReCS
Urinary Tract Infection Fungal MetaADEDB
Urinary Tract Infection Staphylococcal MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Vascular Calcification MetaADEDB
Vascular Insufficiency MetaADEDB
Vascular Occlusion ADReCS
Vena Cava Thrombosis MetaADEDB
Venoocclusive Disease MetaADEDB
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation ADReCS
Ventricular Tachycardia ADReCS
Vision Blurred ADReCS
Vision Disorders MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vitreous Disorder MetaADEDB
Vocal Cord Inflammation MetaADEDB
Vomiting MetaADEDB
Vulvovaginal Pruritus MetaADEDB
Waist Circumference Increased MetaADEDB
Weakness SIDER
Wheeze MetaADEDB
Wound ADReCS
Wound Abscess MetaADEDB
Wound Closure MetaADEDB
Wound Drainage MetaADEDB
Wound Infection MetaADEDB
Wound Infection Staphylococcal MetaADEDB

InAADR: Drug-Protein-ADRs database