InAADR

Drug Information

Drug Name: Norfloxacin (70458-96-7)
PubChem ID: 4539
SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
InchiKey: OGJPXUAPXNRGGI-UHFFFAOYSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents, Antineoplastic Agents, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors, Enzyme Inhibitors, Nucleic Acid Synthesis Inhibitors, Topoisomerase II Inhibitors, Topoisomerase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 319.336
LogP: 1.2683
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 74.57

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Warfarin (81-81-2) Bleeding Antagonistic Uncertain. It is not clear what factors might have been responsible in those cases where the effects of the anticoagulants were increased Norfloxacin and warfarin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Distension ADReCS
Abdominal Mass ADReCS
Abdominal Pain SIDER
Abdominal Pain ADReCS
Abnormal Behaviour MetaADEDB
Abnormal Lfts MetaADEDB
Abortion Induced MetaADEDB
Aching Muscles MetaADEDB
Acidosis ADReCS
Acute Coronary Syndrome ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Failure MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Albuminuria ADReCS
Alcoholic Intoxication MetaADEDB
Allergic Alveolitis MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Allergy ADReCS
Als MetaADEDB
Amniotic Band Syndrome MetaADEDB
Anaemia MetaADEDB
Anaemia Postoperative MetaADEDB
Anal Pruritus ADReCS
Anaphylactic Shock MetaADEDB
Anaphylactoid Reaction ADReCS
Angioedema ADReCS
Anisocytosis MetaADEDB
Anorectal Discomfort ADReCS
Anorexia ADReCS
Anoxia MetaADEDB
Anticonvulsant Drug Level Above Therapeutic MetaADEDB
Anxiety ADReCS
Anxiety Disorder ADReCS
Anxiety Disorders MetaADEDB
Aortic Valve Disease MetaADEDB
Aphthous Stomatitis MetaADEDB
Apoplexy MetaADEDB
Arrhythmia MetaADEDB
Arteriopathic Disease MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asterixis MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Atelectasis MetaADEDB
Automatism MetaADEDB
Azotaemia MetaADEDB
Bacillus Infection MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacteriuria MetaADEDB
Basedow Disease MetaADEDB
Biopsy Bone Abnormal MetaADEDB
Bladder Catheter Replacement MetaADEDB
Bladder Distension MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Gums MetaADEDB
Bleeding Time Prolonged MetaADEDB
Blepharitis MetaADEDB
Blindness Unilateral MetaADEDB
Blister ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol Increased ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Culture Positive MetaADEDB
Blood Electrolytes Decreased MetaADEDB
Blood Glucose Increased ADReCS
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Ph Decreased MetaADEDB
Blood Potassium Increased ADReCS
Blood Pressure Immeasurable MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased ADReCS
Blood Urea Increased ADReCS
Body Temperature Increased ADReCS
Bowel Sounds Abnormal MetaADEDB
Brain Malformation MetaADEDB
Bundle Branch Block Right MetaADEDB
Bursitis ADReCS
C-Reactive Protein Increased MetaADEDB
Candida Infection MetaADEDB
Candidiasis MetaADEDB
Candiduria ADReCS
Capillary Disorder MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardiac Valve Vegetation MetaADEDB
Cardiospasm MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Site Erythema MetaADEDB
Cell Death MetaADEDB
Central Line Infection MetaADEDB
Cerebral Artery Occlusion MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Disorder MetaADEDB
Chest Pain ADReCS
Chest Wall Pain MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Cholestasis ADReCS
Cholestatic Liver Injury MetaADEDB
Chromaturia MetaADEDB
Chromosomal Deletion MetaADEDB
Chromosome Abnormality MetaADEDB
Citrobacter Infection MetaADEDB
Cleft Palate MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Colitis MetaADEDB
Colitis Pseudomembranous MetaADEDB
Confabulation MetaADEDB
Confusional State MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Conjunctivitis MetaADEDB
Consciousness Fluctuating MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Convulsions Generalised SIDER
Corneal Disorder MetaADEDB
Corneal Oedema MetaADEDB
Cramp Muscle SIDER
Crystalluria ADReCS
Cutaneous Vasculitis MetaADEDB
Cylindruria ADReCS
Cystitis MetaADEDB
Cystitis Escherichia MetaADEDB
Cystitis Noninfective MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness ADReCS
Death ADReCS
Decreased Appetite ADReCS
Delusion MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Exfoliative ADReCS
Dermatosis MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Disorientation ADReCS
Diverticular Perforation MetaADEDB
Diverticulosis MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Eruptions MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Dry Mouth ADReCS
Dysarthria MetaADEDB
Dysgeusia ADReCS
Dysmenorrhoea ADReCS
Dyspareunia MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphasia MetaADEDB
Dyspnoea ADReCS
Dystonia MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Echolalia MetaADEDB
Edema MetaADEDB
Electrocardiogram Qt Prolonged ADReCS
Electrolyte Disorder MetaADEDB
Embolism MetaADEDB
Embryo Loss MetaADEDB
Encephalitis Allergic MetaADEDB
Endophthalmitis MetaADEDB
Enlarged Liver MetaADEDB
Enterococcal Sepsis MetaADEDB
Enterocolitis Infectious MetaADEDB
Enthesopathy MetaADEDB
Eosinophil Count Increased ADReCS
Eosinophilia ADReCS
Eosinophilic Cystitis MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epiglottitis MetaADEDB
Epilepsy MetaADEDB
Episcleritis MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Erythema Nodosum MetaADEDB
Escherichia Infection MetaADEDB
Euphoric Mood ADReCS
Explosive Personality Disorder SIDER
Eye Pain MetaADEDB
Eyelid Pain MetaADEDB
Fatigue MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Febrile Neutropenia MetaADEDB
Feeding Disorder MetaADEDB
Flatulence ADReCS
Flu MetaADEDB
Foetor Hepaticus MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Glomerulonephritis MetaADEDB
Glucose-6-Phosphate Dehydrogenase Deficiency ADReCS
Glycosuria ADReCS
Goiter MetaADEDB
Gonorrhea MetaADEDB
Granuloma MetaADEDB
Guillain-Barre Syndrome ADReCS
Haematocrit Decreased ADReCS
Haematoma MetaADEDB
Haematuria ADReCS
Haemodynamic Instability MetaADEDB
Haemolytic Anaemia ADReCS
Haemorrhage Rectum MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Hand Swelling ADReCS
Headache ADReCS
Hearing Impaired MetaADEDB
Heart Rate Increased MetaADEDB
Heartburn ADReCS
Hematoma Subdural MetaADEDB
Hematuria MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Failure ADReCS
Hepatic Necrosis ADReCS
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis ADReCS
Hepatitis B MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury MetaADEDB
Hydronephrosis MetaADEDB
Hyperaesthesia MetaADEDB
Hyperammonaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperparathyroidism MetaADEDB
Hypersensitivity MetaADEDB
Hypertonia MetaADEDB
Hypoaesthesia ADReCS
Hypochromasia MetaADEDB
Hypoglycaemia ADReCS
Hypotension MetaADEDB
Immunodeficiency MetaADEDB
Impaired Self-Care MetaADEDB
Infarction ADReCS
Infection Urinary Tract MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Infusion Site Rash MetaADEDB
Injection Site Dermatitis MetaADEDB
Insomnia ADReCS
Intermittent Explosive Disorder ADReCS
International Normalised Ratio Increased MetaADEDB
Intestinal Fistula MetaADEDB
Intracranial Pressure Increased ADReCS
Irritability ADReCS
Itch MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaundice Obstructive MetaADEDB
Joint Diseases MetaADEDB
Joint Stiffness ADReCS
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Kidney Transplant MetaADEDB
Lacrimation Increased ADReCS
Lactic Dehydrogenase Activity Increased SIDER
Lacunar Infarction MetaADEDB
Large Granular Lymphocytosis MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Lightheadedness SIDER
Lip Dry MetaADEDB
Lip Haemorrhage MetaADEDB
Lipids Increased MetaADEDB
Livedo Reticularis MetaADEDB
Liver Cirrhosis Alcoholic MetaADEDB
Liver Function Test Abnormal ADReCS
Low Back Pain MetaADEDB
Lung Infection MetaADEDB
Lyell MetaADEDB
Lymphocele MetaADEDB
Macrocytosis MetaADEDB
Malabsorption MetaADEDB
Meningorrhagia MetaADEDB
Mental Disorder ADReCS
Metabolic Acidosis ADReCS
Metabolic Encephalopathy MetaADEDB
Metastases To Lung MetaADEDB
Mitral Valve Disease MetaADEDB
Motor Dysfunction MetaADEDB
Motor Retardation MetaADEDB
Mouth Bleeding MetaADEDB
Mouth Ulceration ADReCS
Mucous Membrane Disorder MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Muscle Disorder MetaADEDB
Muscle Fatigue MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness ADReCS
Mutism MetaADEDB
Myalgia ADReCS
Myasthenia MetaADEDB
Myasthenia Gravis ADReCS
Myocardial Infarction ADReCS
Myoclonus ADReCS
Nausea ADReCS
Necrolysis Epidermal MetaADEDB
Necrosis MetaADEDB
Nephritis MetaADEDB
Nephritis Interstitial MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Degeneration MetaADEDB
Nervousness ADReCS
Neuroleptic Malignant Syndrome MetaADEDB
Neuropathy MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutropenia ADReCS
Neutrophil Count Decreased ADReCS
Nystagmus ADReCS
Obstruction MetaADEDB
Odynophagia MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Oliguria MetaADEDB
Onychomadesis MetaADEDB
Orthostatic Hypotension ADReCS
Ovarian Mass MetaADEDB
Pain ADReCS
Pain In Throat MetaADEDB
Pallor MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Paraesthesia ADReCS
Pathogen Resistance MetaADEDB
Pco2 Decreased MetaADEDB
Pemphigus MetaADEDB
Periarthritis MetaADEDB
Peripheral Sensory Neuropathy ADReCS
Personality Disorder ADReCS
Petechia MetaADEDB
Phosphatase Alkaline Increased SIDER
Photosensitivity MetaADEDB
Photosensitivity Reaction ADReCS
Phototoxicity MetaADEDB
Platelet Count Decreased ADReCS
Pneumonia Fungal MetaADEDB
Polyneuropathy MetaADEDB
Portal Vein Thrombosis MetaADEDB
Prescribed Overdose MetaADEDB
Priapism MetaADEDB
Proctalgia ADReCS
Protein Urine Present ADReCS
Proteinuria ADReCS
Proteus Infections MetaADEDB
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Pruritus Genital ADReCS
Pseudomembranous Colitis ADReCS
Pseudomonas Infections MetaADEDB
Psychotic Disorder ADReCS
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Artery Thrombosis MetaADEDB
Purulent Discharge MetaADEDB
Pyelonephritis MetaADEDB
Pyrexia ADReCS
Pyuria MetaADEDB
Raised Liver Function Tests MetaADEDB
Rash ADReCS
Reiter Syndrome MetaADEDB
Renal Colic ADReCS
Renal Failure ADReCS
Respiratory Rate Increased MetaADEDB
Rhabdomyolysis MetaADEDB
Rheumatoid Nodule MetaADEDB
Seizures SIDER
Sensorimotor Disorder MetaADEDB
Seroma MetaADEDB
Serum Creatinine Increased SIDER
Serum Sickness MetaADEDB
Shoulder Pain MetaADEDB
Skin Discolouration MetaADEDB
Skin Test Negative MetaADEDB
Skin Test Positive MetaADEDB
Sleep Disorder ADReCS
Sleep Disturbance SIDER
Somnolence ADReCS
Spina Bifida MetaADEDB
Spinal Myelogram Abnormal MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stiffness SIDER
Stomatitis ADReCS
Streptococcal Bacteraemia MetaADEDB
Swelling ADReCS
Swelling Of Limb SIDER
Swollen Tongue MetaADEDB
Taste Bitter ADReCS
Taste Metallic ADReCS
Tenderness ADReCS
Tendinitis MetaADEDB
Tendon Disorder MetaADEDB
Tendon Rupture ADReCS
Tendonitis ADReCS
Tension ADReCS
Thrombocytopenia ADReCS
Tingling Sensation SIDER
Tinnitus ADReCS
Tongue Exfoliation MetaADEDB
Torsade De Pointes ADReCS
Toxic Epidermal Necrolysis ADReCS
Toxic Skin Eruption MetaADEDB
Transfusion Reaction MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Tubulointerstitial Nephritis ADReCS
Ulcer ADReCS
Ultrasound Abdomen Abnormal MetaADEDB
Upper Limb Fracture MetaADEDB
Ureteral Necrosis MetaADEDB
Urethritis MetaADEDB
Urinary Protein Increased SIDER
Urinary Tract Disorder MetaADEDB
Urinary Tract Infections MetaADEDB
Urine Abnormality MetaADEDB
Urogenital Haemorrhage MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Vaginal Moniliasis MetaADEDB
Vascular Dementia MetaADEDB
Vasculitis ADReCS
Ventricular Arrhythmia ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vitamin B 12 Deficiency MetaADEDB
Vitamin K Decreased MetaADEDB
Vitritis MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Dryness MetaADEDB
White Blood Cell Count Decreased ADReCS
Xyy Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database