InAADR

Drug Information

Drug Name: Nitric Oxide (10102-43-9)
PubChem ID: 145068
SMILES: [N]=O
InchiKey: MWUXSHHQAYIFBG-UHFFFAOYSA-N
Therapeutic Category: Anti-Asthmatic Agents, Antioxidants, Autonomic Agents, Bronchodilator Agents, Cardiovascular Agents, Endothelium-Dependent Relaxing Factors, Free Radical Scavengers, Gasotransmitters, Neurotransmitter Agents, Peripheral Nervous System Agents, Respiratory System Agents, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 30.006
LogP: -0.4471
Ring Count: 0
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 39.37

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Apoptosis Golgi SNAP receptor complex (O95249) Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6,which involve in Three different NO donors, SNAP, NOR3 and NOC7, which induces apoptosis in a beta-cell line, MIN6 cells, in a concentration-dependent manner. [ ADR Type 1 ] Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6 Cell
Apoptosis NOC7 (P00038) Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6,which involves in Three different NO donors, SNAP, NOR3 and NOC7, which induces apoptosis in a beta-cell line, MIN6 cells, in a concentration-dependent manner. [ ADR Type 1 ] Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6 Cell
Apoptosis NOR3 (P00037) Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6,which involve in Three different NO donors, SNAP, NOR3 and NOC7, which induced apoptosis in a beta-cell line, MIN6 cells, in a concentration-dependent manner [ ADR Type 1 ] Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6 Cell

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Sepsis MetaADEDB
Accident MetaADEDB
Acid-Base Balance Disorder Mixed MetaADEDB
Acidosis MetaADEDB
Acute Chest Syndrome MetaADEDB
Acute Lung Injury MetaADEDB
Agranulocytoses MetaADEDB
Alzheimer Disease MetaADEDB
Anal Fissure MetaADEDB
Angina Pectoris MetaADEDB
Anoxia MetaADEDB
Apnea MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Aspiration Bone Marrow MetaADEDB
Asthma MetaADEDB
Atelectasis ADReCS
Atherosclerosis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Automatism MetaADEDB
Bacterial Toxaemia MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Birth Trauma MetaADEDB
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Body Temperature Increased ADReCS
Bradycardia MetaADEDB
Bradycardia Neonatal MetaADEDB
Brain Injuries MetaADEDB
Brain Ischemia MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Neoplasms MetaADEDB
Bronchial Diseases MetaADEDB
Bulging MetaADEDB
Candida Sepsis MetaADEDB
Capillary Leak Syndrome MetaADEDB
Carcinoma Hepatocellular MetaADEDB
Cardiac Arrest Neonatal MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathies MetaADEDB
Cardiomyopathy Neonatal MetaADEDB
Cardiopulmonary Failure PROTECT
Cardiovascular Diseases MetaADEDB
Cardiovascular Disorder MetaADEDB
Cardiovirus Infections MetaADEDB
Carotid Stenosis MetaADEDB
Catheter Sepsis MetaADEDB
Cellulitis ADReCS
Central Nervous System Diseases MetaADEDB
Central Venous Catheterisation MetaADEDB
Central Venous Pressure Increased MetaADEDB
Cerebral Cyst MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarction ADReCS
Cerebral Palsy ADReCS
Cerebral Thrombosis MetaADEDB
Cerebral Ventricle Dilatation MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Cholestasis MetaADEDB
Chorioamnionitis MetaADEDB
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Colitis MetaADEDB
Congenital Infection MetaADEDB
Congenital Small Intestinal Atresia MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Convulsion ADReCS
Coronary Artery Disease MetaADEDB
Craniofacial Abnormalities MetaADEDB
Crest Syndrome ADReCS
Deafness ADReCS
Deafness Neurosensory MetaADEDB
Death Neonatal MetaADEDB
Dementia Vascular MetaADEDB
Device Breakage MetaADEDB
Device Failure MetaADEDB
Device Leakage MetaADEDB
Device Malfunction ADReCS
Device Occlusion MetaADEDB
Diabetes Mellitus Type 1 MetaADEDB
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drug Delivery System Malfunction MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Withdrawal Syndrome ADReCS
Drug-Induced Liver Injury MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Embolism Pulmonary MetaADEDB
Embryo Loss MetaADEDB
Encephalomyelitis Autoimmune Experimental MetaADEDB
Endocarditis MetaADEDB
Endotracheal Intubation Complication MetaADEDB
Enterococcal Sepsis MetaADEDB
Epidermal Necrolysis Toxic MetaADEDB
Extrasystoles Ventricular MetaADEDB
Febrile Convulsion ADReCS
Feeding Disorder Neonatal MetaADEDB
Fetal Diseases MetaADEDB
Fetal Hypoxia MetaADEDB
Flatulence ADReCS
Gait Disturbance ADReCS
Gastroenteritis MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Hypomotility MetaADEDB
Gastrointestinal Stoma Complication MetaADEDB
General Physical Health Deterioration MetaADEDB
Glomerular Filtration Rate Increased MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhage Intracranial MetaADEDB
Headache ADReCS
Headache Disorders Primary MetaADEDB
Hearing Aid User MetaADEDB
Hearing Impaired ADReCS
Hearing Loss MetaADEDB
Heart Diseases MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hydrocephalus MetaADEDB
Hyperalgesia MetaADEDB
Hyperbilirubinaemia PROTECT
Hypercapnia MetaADEDB
Hyperemia MetaADEDB
Hyperglycaemia ADReCS
Hyperplasia MetaADEDB
Hypertension MetaADEDB
Hypertension Pulmonary MetaADEDB
Hypertrophy Left Ventricular MetaADEDB
Hypokalaemia PROTECT
Hypotension ADReCS
Hypoxemia SIDER
Hypoxia ADReCS
Ileal Perforation MetaADEDB
Incorrect Dose Administered PROTECT
Infantile Apnoeic Attack MetaADEDB
Infarction ADReCS
Infection ADReCS
Infertility Male MetaADEDB
Inflammation MetaADEDB
Intestinal Diseases MetaADEDB
Intestinal Obstruction MetaADEDB
Intestinal Perforation MetaADEDB
Intestinal Stenosis MetaADEDB
Intraventricular Haemorrhage MetaADEDB
Intraventricular Haemorrhage Neonatal MetaADEDB
Kidney Diseases MetaADEDB
Klebsiella Infection MetaADEDB
Laryngeal Stenosis MetaADEDB
Late Metabolic Acidosis Of Newborn MetaADEDB
Left Atrial Dilatation MetaADEDB
Leishmaniasis MetaADEDB
Lung Consolidation MetaADEDB
Lung Diseases MetaADEDB
Lung Disorder ADReCS
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Injury MetaADEDB
Lymphoma MetaADEDB
Meconium Aspiration Syndrome MetaADEDB
Medical Device Complication MetaADEDB
Meningitis Bacterial MetaADEDB
Methaemoglobinaemia PROTECT
Methemoglobinemia MetaADEDB
Migraine Disorders MetaADEDB
Migraine Without Aura MetaADEDB
Morphine Dependence MetaADEDB
Motor Neuron Disease MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple-Drug Resistance MetaADEDB
Mycoplasma Infections MetaADEDB
Myocardial Ischemia MetaADEDB
Necrosis MetaADEDB
Necrotising Colitis MetaADEDB
Necrotising Enterocolitis Neonatal MetaADEDB
Neonatal Anuria MetaADEDB
Neonatal Hypotension MetaADEDB
Neonatal Hypoxia MetaADEDB
Neonatal Intestinal Obstruction MetaADEDB
Neonatal Respiratory Acidosis MetaADEDB
Neonatal Respiratory Distress Syndrome MetaADEDB
Neonatal Respiratory Failure MetaADEDB
Nerve Degeneration MetaADEDB
Neural Tube Defects MetaADEDB
Neuritis Autoimmune Experimental MetaADEDB
Neurodegenerative Diseases MetaADEDB
No Match PROTECT
No Therapeutic Response MetaADEDB
Oedema ADReCS
Oedema Neonatal MetaADEDB
Oliguria MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Oxygen Saturation Increased MetaADEDB
Pain MetaADEDB
Pallor MetaADEDB
Paralysis ADReCS
Patent Ductus Arteriosis MetaADEDB
Patent Ductus Arteriosus Repair MetaADEDB
Peritoneal Dialysis MetaADEDB
Peritonitis MetaADEDB
Periventricular Leukomalacia MetaADEDB
Persistent Fetal Circulation Syndrome MetaADEDB
Phlebitis Infective MetaADEDB
Phlebothrombosis MetaADEDB
Platelet Function Test Abnormal MetaADEDB
Pneumatosis MetaADEDB
Pneumonia Aspiration MetaADEDB
Pneumothorax MetaADEDB
Polycythaemia MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Premature Baby MetaADEDB
Primary Graft Dysfunction MetaADEDB
Primary Mediastinal Large B-Cell Lymphoma MetaADEDB
Procedural Complication MetaADEDB
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Arterial Wedge Pressure Decreased MetaADEDB
Pulmonary Artery Dilatation MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Haemorrhage ADReCS
Pulmonary Hypertensive Crisis MetaADEDB
Pulmonary Interstitial Emphysema Syndrome MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Oedema Neonatal MetaADEDB
Pulmonary Veno-Occlusive Disease MetaADEDB
Rebound Effect PROTECT
Reflexes Abnormal MetaADEDB
Renal Failure Neonatal MetaADEDB
Reperfusion Injury MetaADEDB
Respiration Abnormal MetaADEDB
Respiratory Disorder Neonatal MetaADEDB
Respiratory Distress Syndrome Adult MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Tract Infection PROTECT
Respiratory Tract Inflammation PROTECT
Retinopathy Of Prematurity MetaADEDB
Right Heart Failure MetaADEDB
Right Ventricular Hypertrophy MetaADEDB
Schistosomiasis Mansoni MetaADEDB
Seizures MetaADEDB
Sepsis ADReCS
Septic Shock MetaADEDB
Sexually Transmitted Disease SIDER
Skin Discolouration MetaADEDB
Small For Dates Baby MetaADEDB
Small Intestinal Perforation MetaADEDB
Speech Disorder Developmental MetaADEDB
Spinal Cord Diseases MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Status Epilepticus MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stomach Ulcer MetaADEDB
Streptococcal Bacteraemia MetaADEDB
Streptococcal Identification Test Positive MetaADEDB
Stridor ADReCS
Substance Withdrawal Syndrome MetaADEDB
Suture Related Complication MetaADEDB
Tachycardia ADReCS
Therapy Non-Responder MetaADEDB
Thrombocytopenia PROTECT
Thrombosis MetaADEDB
Tinea Pedis MetaADEDB
Urinary Bladder Overactive MetaADEDB
Varicocele MetaADEDB
Vascular Headaches MetaADEDB
Vascular System Injuries MetaADEDB
Ventricular Fibrillation MetaADEDB
Wound Dehiscence MetaADEDB
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database