InAADR

Drug Information

Drug Name: Nimodipine (66085-59-4)
PubChem ID: 4497
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
InchiKey: UIAGMCDKSXEBJQ-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 418.446
LogP: 2.9708
Ring Count: 1
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 117

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Accident MetaADEDB
Acne ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Adams-Stokes Syndrome MetaADEDB
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase Increased ADReCS
Als MetaADEDB
Altered State Of Consciousness ADReCS
Amnesia MetaADEDB
Amnestic Disorder MetaADEDB
Anaemia ADReCS
Aneurysm Ruptured MetaADEDB
Angiopathy MetaADEDB
Anoxia MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anxiety Disorders MetaADEDB
Apnea MetaADEDB
Application Site Burn MetaADEDB
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Bipolar Disorder MetaADEDB
Bleeding Gums MetaADEDB
Blood Alcohol Increased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Glucose Increased ADReCS
Blood Lactate Dehydrogenase Increased ADReCS
Blood Pressure Abnormal ADReCS
Blood Pressure Decreased ADReCS
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Urea Increased SIDER
Bone Pain MetaADEDB
Bradycardia ADReCS
Brain Edema MetaADEDB
Brain Infarction MetaADEDB
Brain Ischemia MetaADEDB
Bulbar Palsy MetaADEDB
Bulging MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathies MetaADEDB
Cardiotoxicity MetaADEDB
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Catheter Related Complication MetaADEDB
Cerebral Hypoperfusion MetaADEDB
Cerebral Infarction MetaADEDB
Cerebral Vasoconstriction MetaADEDB
Cerebrovascular Disorders MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cirrhosis MetaADEDB
Colonic Pseudo-Obstruction MetaADEDB
Coma MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Corneal Abrasion MetaADEDB
Cramp Muscle SIDER
Deafness MetaADEDB
Deep Vein Thrombosis ADReCS
Dementia MetaADEDB
Demyelination MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Diarrhoea ADReCS
Disseminated Intravascular Coagulation ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Toxicity ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dysphasia MetaADEDB
Dysphoria MetaADEDB
Dyspnoea ADReCS
Electrocardiogram Abnormal ADReCS
Encephalitis MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalitis Herpes MetaADEDB
Facial Palsy MetaADEDB
Fasting ADReCS
Feeding Tube Insertion MetaADEDB
Fever MetaADEDB
Flooding MetaADEDB
Fluid Overload MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Disorder MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Lavage MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Symptom Nos SIDER
Haematoma ADReCS
Head Injury MetaADEDB
Headache ADReCS
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis B Positive MetaADEDB
Hot Flash MetaADEDB
Hyperammonaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperkinesis MetaADEDB
Hypertension ADReCS
Hypertension Pulmonary MetaADEDB
Hypertrophy Left Ventricular MetaADEDB
Hyponatraemia ADReCS
Hypotension ADReCS
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ill-Defined Disorder MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Inner Ear Inflammation MetaADEDB
Intestinal Obstruction MetaADEDB
Intracranial Aneurysm MetaADEDB
Intracranial Hypotension MetaADEDB
Ischemia MetaADEDB
Ischemic Attack Transient MetaADEDB
Jaundice ADReCS
Keratitis Sicca MetaADEDB
Lactic Dehydrogenase Activity Increased SIDER
Lightheadedness SIDER
Liver Function Test Abnormal ADReCS
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Meningorrhagia MetaADEDB
Migraine Disorders MetaADEDB
Miosis MetaADEDB
Monoparesis MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Mycosis Fungoides MetaADEDB
Mydriasis MetaADEDB
Nausea ADReCS
Necrosis MetaADEDB
Neumonia MetaADEDB
Neurodegenerative Diseases MetaADEDB
Neurological Decompensation ADReCS
No Therapeutic Response MetaADEDB
Oedema ADReCS
Pain ADReCS
Palpitations ADReCS
Pharmaceutical Product Complaint MetaADEDB
Phosphatase Alkaline Increased SIDER
Platelet Count Decreased ADReCS
Poor Peripheral Circulation MetaADEDB
Poor Quality Drug Administered MetaADEDB
Portal Hypertensive Gastropathy MetaADEDB
Post Procedural Complication MetaADEDB
Procedural Complication MetaADEDB
Pruritus ADReCS
Pruritus Generalised MetaADEDB
Rash ADReCS
Respiration Disorders MetaADEDB
Rhagades MetaADEDB
Ruptured Cerebral Aneurysm MetaADEDB
Seizures MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinus Arrest Cardiac MetaADEDB
Sinusitis MetaADEDB
Sleep Disorder MetaADEDB
Spinal Myelogram Abnormal MetaADEDB
Sputum Culture Positive MetaADEDB
Status Epilepticus MetaADEDB
Stroke MetaADEDB
Subarachnoid Haemorrhage ADReCS
Subarachnoid Hemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sweating Increased SIDER
Tachycardia ADReCS
Thrombocytopenia ADReCS
Thrombosis ADReCS
Tinnitus MetaADEDB
Tongue Neoplasm MetaADEDB
Toxic Encephalopathy MetaADEDB
Transfusion-Related Acute Lung Injury MetaADEDB
Transient Ischaemic Attack MetaADEDB
Vascular Diseases MetaADEDB
Vasospasm ADReCS
Vasospasm Intracranial MetaADEDB
Venous Thrombosis ADReCS
Vomiting ADReCS
Wheezing ADReCS
Wound Drainage MetaADEDB
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database