InAADR

Drug Information

Drug Name: Naltrexone (16590-41-3)
PubChem ID: 5360515
SMILES: C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O
InchiKey: DQCKKXVULJGBQN-XFWGSAIBSA-N
Therapeutic Category: Central Nervous System Agents, Narcotic Antagonists, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 341.407
LogP: 1.5254
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 70

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Dreams ADReCS
Abnormal Vision MetaADEDB
Abortion Missed ADReCS
Abscess ADReCS
Accident MetaADEDB
Accident At Work MetaADEDB
Accidental Overdose MetaADEDB
Ache SIDER
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acne ADReCS
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenitis SIDER
Adhesion MetaADEDB
Administration Site Pain MetaADEDB
Affective Disorder MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Air Embolism MetaADEDB
Alanine Aminotransferase MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alcohol Consumption MetaADEDB
Alcohol Poisoning MetaADEDB
Alcohol Withdrawal Syndrome ADReCS
Alcohol-Induced Disorders MetaADEDB
Alcohol-Related Disorders MetaADEDB
Alcoholism MetaADEDB
Allergies MetaADEDB
Alopecia ADReCS
Alpha-1 Anti-Trypsin Increased MetaADEDB
Alveolitis MetaADEDB
Amphetamine-Related Disorders MetaADEDB
Anaemia MetaADEDB
Analgesia MetaADEDB
Anaphylactic Shock ADReCS
Aneurysm ADReCS
Angina Pectoris ADReCS
Angina Unstable ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Ankylosing Spondylitis MetaADEDB
Anorexia ADReCS
Anterograde Amnesia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Appetite Absent SIDER
Appetite Disorder ADReCS
Arrhythmia MetaADEDB
Arterial Aneurysm SIDER
Arterial Occlusion SIDER
Arterial Occlusive Disease ADReCS
Arteriosclerosis ADReCS
Arteriosclerosis Coronary Artery ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Asystole MetaADEDB
Atherosclerosis SIDER
Atrial Fibrillation ADReCS
Attempted Suicide MetaADEDB
Autistic Disorder MetaADEDB
Autonomic Instability MetaADEDB
Back Pain ADReCS
Bacterial Infection MetaADEDB
Bad Dreams SIDER
Balance Disorder MetaADEDB
Bile Duct Obstruction MetaADEDB
Bipolar Disorder MetaADEDB
Bipolar I Disorder MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Creatine Phosphokinase Abnormal ADReCS
Blood Creatinine Normal ADReCS
Blood Glucose Abnormal MetaADEDB
Blood In Urine MetaADEDB
Blood Pressure Abnormal ADReCS
Blood Pressure Fluctuation ADReCS
Blood Pressure Increased ADReCS
Body Temperature Increased ADReCS
Bowel Movement Irregularity MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Brain Damage MetaADEDB
Brain Oedema MetaADEDB
Bronchiectasis MetaADEDB
Bronchitis ADReCS
Bruxism MetaADEDB
Bulging MetaADEDB
Burning Sensation ADReCS
Buttock Pain MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Sepsis MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Catalepsy MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cellulitis ADReCS
Cerebellar Infarction MetaADEDB
Cerebral Arterial Aneurysm SIDER
Cerebral Calcification MetaADEDB
Cerebrovascular Accident ADReCS
Ceruloplasmin Increased MetaADEDB
Cervical Adenitis SIDER
Change In Blood Pressure SIDER
Chest Discomfort ADReCS
Chest Pain ADReCS
Chest Tightness ADReCS
Chill MetaADEDB
Chills ADReCS
Cholecystitis ADReCS
Cholecystitis Acute ADReCS
Cholecystitis Chronic MetaADEDB
Cholecystitis Infective MetaADEDB
Cholelithiasis ADReCS
Chronic Obstructive Airway Disease MetaADEDB
Chronic Obstructive Pulmonary Disease ADReCS
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cold Feet SIDER
Colitis ADReCS
Completed Suicide ADReCS
Complication Of Pregnancy ADReCS
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Conjunctivitis ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Constricted Affect MetaADEDB
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Creatinine Normal SIDER
Crying ADReCS
Csf Lymphocyte Count Increased MetaADEDB
Csf Protein MetaADEDB
Culture Wound Positive MetaADEDB
Cutaneous Ulcer MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytolytic Hepatitis ADReCS
Death ADReCS
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Deep Vein Thrombosis ADReCS
Dehydration ADReCS
Delirium ADReCS
Demyelination MetaADEDB
Depressed Mood ADReCS
Depression ADReCS
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatitis Seborrheic MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Difficulty Sleeping SIDER
Diplopia MetaADEDB
Discomfort ADReCS
Disorder Lung MetaADEDB
Disorientation ADReCS
Disseminated Lupus Erythematosus MetaADEDB
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Administration Error MetaADEDB
Drug Dispensing Error MetaADEDB
Drug Eruptions MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Ineffective MetaADEDB
Drug Interaction MetaADEDB
Drug Screen Positive MetaADEDB
Drug Tolerance MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal MetaADEDB
Dry Mouth ADReCS
Duodenitis MetaADEDB
Dysgeusia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dysphonia ADReCS
Dysphoria MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Ear Discomfort ADReCS
Ecchymoses MetaADEDB
Ecchymosis ADReCS
Ejaculation Delayed ADReCS
Electrocardiogram Change ADReCS
Electromechanical Dissociation MetaADEDB
Embolism ADReCS
Emotional Distress ADReCS
Endocardial Fibrosis MetaADEDB
Energy Increased ADReCS
Enterobacter Infection MetaADEDB
Eosinophilic Pneumonia ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erosive Gastritis MetaADEDB
Erythema MetaADEDB
Erythrodermic Psoriasis MetaADEDB
Eschar MetaADEDB
Euphoric Mood ADReCS
Exanthema MetaADEDB
Excessive Flatulence SIDER
Excessive Sleepiness MetaADEDB
Exhaustion SIDER
Extremity Pain MetaADEDB
Eye Disorder SIDER
Eye Swelling ADReCS
Face Oedema ADReCS
Facial Bones Fracture MetaADEDB
Faeces Pale MetaADEDB
Family Stress MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Drunk MetaADEDB
Feeling Hot ADReCS
Fibromyalgia MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Foot Fracture MetaADEDB
Foreign Body Aspiration MetaADEDB
Fractured Pelvis Nos MetaADEDB
Frequent Bowel Movements ADReCS
Frequent Headaches SIDER
Galactorrhea MetaADEDB
Gambling MetaADEDB
Gas SIDER
Gastric Disorder ADReCS
Gastric Ulcer MetaADEDB
Gastroenteritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Erosion MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Tract Irritation ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Condition MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Granulocyte Count Increased MetaADEDB
Groin Pain ADReCS
Gun Shot Wound MetaADEDB
Haemoglobin ADReCS
Haemolysis MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage ADReCS
Haemorrhoids ADReCS
Hallucination ADReCS
Hallucinations MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heat Exhaustion ADReCS
Heat Rash ADReCS
Hemisensory Neglect MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis C ADReCS
Hepatobiliary Disease SIDER
Hepatocellular Injury ADReCS
Heroin Dependence MetaADEDB
Herpes Labialis ADReCS
Herpes Zoster MetaADEDB
Hiv Infection ADReCS
Hoarseness SIDER
Hot Flush ADReCS
Hyperalgesia MetaADEDB
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hyperinsulinism MetaADEDB
Hyperkeratosis MetaADEDB
Hyperkinesia ADReCS
Hyperkinesis MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypersensitivity ADReCS
Hypersexuality MetaADEDB
Hypertension ADReCS
Hyperventilation ADReCS
Hypokalaemia MetaADEDB
Hyporeflexia MetaADEDB
Hypotension MetaADEDB
Idiopathic Thrombocytopenic Purpura ADReCS
Ileus ADReCS
Ileus Paralytic ADReCS
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Immunoglobulins Decreased MetaADEDB
Implant Site Pain MetaADEDB
Incorrect Dose Administered MetaADEDB
Increased Appetite ADReCS
Increased Thirst ADReCS
Increased Upper Airway Secretion ADReCS
Induration ADReCS
Infarction ADReCS
Infection ADReCS
Infection In An Immunocompromised Host MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Inhibitory Drug Interaction MetaADEDB
Injection Site Bruising SIDER
Injection Site Erosion MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Haematoma ADReCS
Injection Site Haemorrhage ADReCS
Injection Site Induration ADReCS
Injection Site Infection MetaADEDB
Injection Site Inflammation MetaADEDB
Injection Site Mass MetaADEDB
Injection Site Nodule MetaADEDB
Injection Site Pain ADReCS
Injection Site Pruritus ADReCS
Injection Site Reaction ADReCS
Injection Site Vesicles MetaADEDB
Insomnia ADReCS
Intentional Self-Injury MetaADEDB
Intestinal Congestion MetaADEDB
Intracranial Aneurysm ADReCS
Irritability ADReCS
Ischaemic Stroke ADReCS
Joint Stiffness ADReCS
Klebsiella Infection MetaADEDB
Langerhans Cell Granulomatosis MetaADEDB
Laryngitis ADReCS
Lethargy ADReCS
Libido Decreased ADReCS
Libido Disorder ADReCS
Limb Injury MetaADEDB
Lipase MetaADEDB
Liver Injury ADReCS
Loss Of Consciousness ADReCS
Lung Disorder ADReCS
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lymphadenitis ADReCS
Lymphadenopathy ADReCS
Malaise ADReCS
Mediastinal Disorder ADReCS
Meningoencephalitis Herpetic MetaADEDB
Menopausal Symptoms ADReCS
Mental Disability ADReCS
Mental Disorder SIDER
Mental Impairment ADReCS
Mental Retardation ADReCS
Metabolic Disorder MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Migraine ADReCS
Miosis MetaADEDB
Mitral Valve Disease MetaADEDB
Mood Disorder Due To A General Medical Condition MetaADEDB
Morphine Dependence MetaADEDB
Mouth Injury MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscle Strain ADReCS
Muscle Twitching ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Mycobacterium Tuberculosis Infection MetaADEDB
Myocardial Infarction ADReCS
Nasal Congestion ADReCS
Nasal Disorder ADReCS
Nasal Septum Deviation MetaADEDB
Nasopharyngeal Neoplasm Benign MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Neonatal Disorder ADReCS
Nervous System Diseases MetaADEDB
Nervous System Disorder SIDER
Nervousness ADReCS
Neuralgia MetaADEDB
Night Sweats ADReCS
Nightmare ADReCS
No Therapeutic Response MetaADEDB
Nodule ADReCS
Obsessive-Compulsive Disorder SIDER
Obstructive Airways Disorder ADReCS
Occult Blood Positive MetaADEDB
Odynophagia MetaADEDB
Oedema ADReCS
Oily Skin ADReCS
Open Wound MetaADEDB
Opioid-Related Disorders MetaADEDB
Optic Neuritis MetaADEDB
Oral Herpes ADReCS
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Ossicle Disorder MetaADEDB
Otitis Media Chronic MetaADEDB
Ovarian Neoplasms MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Palatal Oedema MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Panic Attack ADReCS
Panic Disorder MetaADEDB
Panic Reaction ADReCS
Paraesthesia ADReCS
Paranoia ADReCS
Peripheral Coldness ADReCS
Perirectal Abscess ADReCS
Persistent Generalised Lymphadenopathy SIDER
Petechia MetaADEDB
Pharyngitis ADReCS
Pharyngitis Streptococcal ADReCS
Pharyngolaryngeal Pain SIDER
Phlebitis ADReCS
Phlebothrombosis MetaADEDB
Photosensitive Rash MetaADEDB
Photosensitivity Reaction ADReCS
Pitting Oedema MetaADEDB
Platelet Count MetaADEDB
Platelet Count Abnormal MetaADEDB
Platelet Count Decreased ADReCS
Pneumonia ADReCS
Pollakiuria ADReCS
Poor Quality Sleep ADReCS
Postpartum Disorder ADReCS
Prenatal Exposure Delayed Effects MetaADEDB
Pruritus ADReCS
Psychoses MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Embolism ADReCS
Pupil Fixed MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Papular ADReCS
Regurgitation MetaADEDB
Respiratory Tract Infection ADReCS
Restlessness ADReCS
Retinal Artery Occlusion ADReCS
Rhinitis Seasonal ADReCS
Rhinorrhoea ADReCS
Rigors SIDER
Sacroiliitis MetaADEDB
Scar MetaADEDB
Schizophrenia MetaADEDB
Seasonal Allergy ADReCS
Seborrhoeic Dermatitis SIDER
Sedation ADReCS
Seizures MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock ADReCS
Shock Septic MetaADEDB
Sinus Congestion ADReCS
Sinus Disorder ADReCS
Sinus Headache ADReCS
Sinusitis ADReCS
Sjogren Syndrome MetaADEDB
Sleep Disorder ADReCS
Sleep Initiation And Maintenance Disorders MetaADEDB
Sluggishness ADReCS
Sneezing ADReCS
Social Fear MetaADEDB
Somnolence ADReCS
Spleen Congestion MetaADEDB
Stiff Back SIDER
Stiffness SIDER
Substance Withdrawal Syndrome MetaADEDB
Suicidal Behaviour ADReCS
Suicidal Ideation ADReCS
Suicide SIDER
Suicide Attempt ADReCS
Sweating SIDER
Sweating Increased SIDER
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tardive Dyskinesia MetaADEDB
Tearfulness ADReCS
Tenderness ADReCS
Tension ADReCS
Thinking Abnormal ADReCS
Thirst ADReCS
Throat Sore SIDER
Throat Tightness MetaADEDB
Thrombocytopenic Purpura ADReCS
Thrombosis ADReCS
Tibia Fracture MetaADEDB
Tics MetaADEDB
Tinea Pedis ADReCS
Tinnitus ADReCS
Tobacco Use Disorder MetaADEDB
Tobacco User MetaADEDB
Tooth Abscess ADReCS
Toothache ADReCS
Tourette Syndrome MetaADEDB
Tracheal Obstruction MetaADEDB
Transmission Of An Infectious Agent Via A Medicinal Product MetaADEDB
Treatment Noncompliance MetaADEDB
Tremor ADReCS
Tricuspid Valve Disease MetaADEDB
Ulcer ADReCS
Unevaluable Event MetaADEDB
Unresponsive To Verbal Stimuli MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upset Stomach SIDER
Urinary Tract Infection ADReCS
Urticaria ADReCS
Vascular Purpura ADReCS
Venous Thrombosis ADReCS
Vertebral Artery Occlusion MetaADEDB
Vision Blurred ADReCS
Visual Impairment ADReCS
Vocal Cord Paralysis MetaADEDB
Vomiting ADReCS
Walking Aid User MetaADEDB
Weight Decreased ADReCS
Weight Increased ADReCS
Weight Loss MetaADEDB
White Blood Cell Count Increased ADReCS
White Blood Cell Disorder MetaADEDB
Withdrawal Syndrome ADReCS
Wound Infection Pseudomonas MetaADEDB
Wrong Drug Administered MetaADEDB
Xerostomia MetaADEDB
Yawning ADReCS

InAADR: Drug-Protein-ADRs database