InAADR

Drug Information

Drug Name: Milnacipran (92623-85-3)
PubChem ID: 65833
SMILES: CCN(CC)C(=O)[C@@]1(C[C@@H]1CN)C2=CC=CC=C2
InchiKey: GJJFMKBJSRMPLA-HIFRSBDPSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Uptake Inhibitors, Antidepressive Agents, Central Nervous System Agents, Membrane Transport Modulators, Neurotransmitter Agents, Neurotransmitter Uptake Inhibitors, Psychotropic Drugs, Serotonin Agents, Serotonin Uptake Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 246.354
LogP: 1.7714
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.33

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Behaviour MetaADEDB
Abnormal Movements MetaADEDB
Abulia MetaADEDB
Accelerated Hypertension MetaADEDB
Accommodation Disorder ADReCS
Activation Syndrome MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Altered State Of Consciousness MetaADEDB
Amnesia MetaADEDB
Anaesthesia MetaADEDB
Angiopathy ADReCS
Anorexia ADReCS
Anovulatory MetaADEDB
Anticholinergic Syndrome MetaADEDB
Antidepressant Drug Level Above Therapeutic MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Anxiety ADReCS
Apallic Syndrome MetaADEDB
Apathy MetaADEDB
Apnea MetaADEDB
Appendicitis MetaADEDB
Areflexia MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Attempted Suicide MetaADEDB
Autism MetaADEDB
Automatism MetaADEDB
Bacteria Stool Identified MetaADEDB
Bipolar I Disorder MetaADEDB
Bladder Pain ADReCS
Bladder Retention MetaADEDB
Blepharospasm MetaADEDB
Blood Alcohol Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Oestrogen Decreased MetaADEDB
Blood Osmolarity Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Pressure Increased ADReCS
Blood Sodium MetaADEDB
Blood Test Abnormal MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Zinc Decreased MetaADEDB
Body Temperature Increased ADReCS
Bradypnoea MetaADEDB
Breast Disorder SIDER
Bruxism MetaADEDB
C-Reactive Protein Increased MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Disorder ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiotoxicity MetaADEDB
Cataract MetaADEDB
Catheter Related Infection MetaADEDB
Cerebral Disorder MetaADEDB
Cervical Root Pain MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Chills ADReCS
Coma MetaADEDB
Completed Suicide MetaADEDB
Concomitant Disease Progression MetaADEDB
Confabulation MetaADEDB
Connective Tissue Disorder SIDER
Consciousness Fluctuating MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Contracture MetaADEDB
Contusion ADReCS
Convulsion ADReCS
Coronary Artery Stenosis MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cystitis ADReCS
Cystitis Noninfective ADReCS
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Delirium ADReCS
Depressed Level Of Consciousness MetaADEDB
Depression ADReCS
Derealisation MetaADEDB
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Interaction MetaADEDB
Drug Screen Positive MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Syndrome Neonatal MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dysuria ADReCS
Early Morning Awakening MetaADEDB
Ecchymoses MetaADEDB
Edema Extremities MetaADEDB
Ejaculation Delayed MetaADEDB
Ejaculation Disorder ADReCS
Ejaculation Failure ADReCS
Elbow Operation MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Embolism Pulmonary MetaADEDB
Endocrine Disorder SIDER
Enteritis MetaADEDB
Erectile Dysfunction ADReCS
Erythema ADReCS
Erythema Multiforme ADReCS
Esophageal Rupture MetaADEDB
Euphoric Mood MetaADEDB
Excessive Salivation MetaADEDB
Excessive Thirst MetaADEDB
Extrapyramidal Disorder MetaADEDB
Eye Disorder SIDER
Eye Swelling MetaADEDB
Face Pain MetaADEDB
Fall ADReCS
Fatigue ADReCS
Fatty Liver MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Femoral Neck Fracture MetaADEDB
Flatulence ADReCS
Flooding MetaADEDB
Flushing ADReCS
Foetal Growth Retardation MetaADEDB
Galactorrhoea ADReCS
Gambling MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Goiter MetaADEDB
Grand Mal Convulsion ADReCS
Haemoglobin Abnormal MetaADEDB
Haemorrhoids MetaADEDB
Hallucination ADReCS
Head Titubation MetaADEDB
Headache ADReCS
Heart Rate Increased ADReCS
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis ADReCS
Hepatitis C MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatobiliary Disease SIDER
Herpes Zoster MetaADEDB
Homicidal Ideation MetaADEDB
Hormone Level Abnormal SIDER
Hospitalisation MetaADEDB
Hot Flush ADReCS
Humerus Fracture MetaADEDB
Hyperacusia MetaADEDB
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hyperprolactinaemia ADReCS
Hyperreflexia MetaADEDB
Hypersexuality MetaADEDB
Hypertension ADReCS
Hypertensive SIDER
Hypertensive Crisis ADReCS
Hypoaesthesia ADReCS
Hypokinesia MetaADEDB
Hyponatraemia ADReCS
Hypophagia MetaADEDB
Hypoxia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Impulse-Control Disorder MetaADEDB
Impulsive Behaviour MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection ADReCS
Injection Site Infection MetaADEDB
Injection Site Paraesthesia MetaADEDB
Insomnia ADReCS
Intention Tremor MetaADEDB
Intentional Drug Misuse MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Irritability ADReCS
Labile Blood Pressure MetaADEDB
Lacunar Infarction MetaADEDB
Large Intestine Perforation MetaADEDB
Laryngospasm MetaADEDB
Leukopenia ADReCS
Libido Decreased ADReCS
Life Support MetaADEDB
Light Sensitivity MetaADEDB
Local Swelling MetaADEDB
Loss Of Consciousness ADReCS
Lymphocyte Stimulation Test Positive MetaADEDB
Malignant Pleural Effusion MetaADEDB
Malignant Syndrome Nos SIDER
Mania MetaADEDB
Menopausal Symptoms ADReCS
Menstruation Delayed MetaADEDB
Mental Disorder SIDER
Mental Status Changes MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Eye MetaADEDB
Metastases To Pancreas MetaADEDB
Micturition Disorder MetaADEDB
Migraine ADReCS
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple-Drug Resistance MetaADEDB
Muscle Tightness MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Neonatal Asphyxia MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neuralgia MetaADEDB
Neuroleptic Malignant Syndrome ADReCS
Neurosis MetaADEDB
Neutropenia ADReCS
Neutrophil Count Decreased MetaADEDB
Night Sweats ADReCS
Nystagmus MetaADEDB
Obstructive Airways Disorder MetaADEDB
Obstructive Uropathy MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oligohydramnios MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palpitations ADReCS
Paraesthesia ADReCS
Parkinson MetaADEDB
Parkinsonian Gait MetaADEDB
Parkinsonism ADReCS
Persecutory Delusion MetaADEDB
Personality Disorder MetaADEDB
Phobia MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumomediastinum MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Poisoning ADReCS
Pollakiuria MetaADEDB
Polychondritis MetaADEDB
Polyuria MetaADEDB
Poor Peripheral Circulation MetaADEDB
Poriomania MetaADEDB
Post Herpetic Neuralgia MetaADEDB
Potentiating Drug Interaction MetaADEDB
Procedural Complication ADReCS
Proctocolitis MetaADEDB
Prostatitis ADReCS
Protein Total Decreased MetaADEDB
Pruritus ADReCS
Psychiatric Symptom MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Infarction MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renin Increased MetaADEDB
Respiratory Disorder ADReCS
Respiratory Disorder Neonatal MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Bleeding MetaADEDB
Rhabdomyolysis ADReCS
Right Heart Failure MetaADEDB
Scrotal Pain ADReCS
Self Injurious Behaviour MetaADEDB
Serotonin Syndrome ADReCS
Sinus Bradycardia MetaADEDB
Skin Chapped MetaADEDB
Skin Disorder ADReCS
Soliloquy MetaADEDB
Somnolence ADReCS
Stent Placement MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress ADReCS
Subcutaneous Haematoma MetaADEDB
Subdural Hygroma MetaADEDB
Subileus MetaADEDB
Sudden Death MetaADEDB
Supraventricular Tachycardia ADReCS
Sweating SIDER
Swelling ADReCS
Syncope Vasovagal MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Tension Headache ADReCS
Testicular Pain ADReCS
Testicular Swelling ADReCS
Thrombocytopenia ADReCS
Tinnitus MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheo-Oesophageal Fistula MetaADEDB
Tremor ADReCS
Tri-Iodothyronine Free Decreased MetaADEDB
Type Iii Immune Complex Mediated Reaction MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urethral Disorder SIDER
Urethral Pain ADReCS
Urinary Hesitation ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urine Flow Decreased ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Waist Circumference Increased MetaADEDB
Weight Abnormal ADReCS
Weight Decreased ADReCS
Wound Infection Staphylococcal MetaADEDB
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database