InAADR

Drug Information

Drug Name: Midazolam (59467-70-8)
PubChem ID: 4192
SMILES: CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
InchiKey: DDLIGBOFAVUZHB-UHFFFAOYSA-N
Therapeutic Category: Adjuvants, Anesthetics, Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, GABA Agents, GABA Modulators, Hypnotics and Sedatives, Neurotransmitter Agents, Psychotropic Drugs, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 325.774
LogP: 4.32422
Ring Count: 3
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 30.18

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Cns Depression Food–drug interaction: grapefruit juice augments drug bioavailabilityFmechanism, extent and relevance

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Movements MetaADEDB
Abortion MetaADEDB
Abscess MetaADEDB
Abscess Drainage MetaADEDB
Accident MetaADEDB
Accommodation Disorder MetaADEDB
Acidosis MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Adrenal Neoplasm MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Aggression ADReCS
Aggressive Reaction SIDER
Agitated MetaADEDB
Agitation ADReCS
Airway Obstruction MetaADEDB
Airway Obstruction Nos SIDER
Akathisia Drug-Induced MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Alcoholism MetaADEDB
Alveolitis MetaADEDB
Alzheimer Disease MetaADEDB
Amenorrhea MetaADEDB
Ammonia Increased MetaADEDB
Amnesia MetaADEDB
Amnesia Anterograde MetaADEDB
Amnesia Retrograde MetaADEDB
Anaemia MetaADEDB
Anaesthesia ADReCS
Anaesthetic Complication MetaADEDB
Anaesthetic Complication Pulmonary MetaADEDB
Anaesthetic Complication Vascular MetaADEDB
Analgesic Drug Level Above Therapeutic MetaADEDB
Anaphylactic Reaction MetaADEDB
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anger PROTECT
Anoxia MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anterograde Amnesia ADReCS
Antidepressant Drug Clearance Decreased MetaADEDB
Anxiety ADReCS
Aphasia MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Apoplexy MetaADEDB
Argumentativeness SIDER
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspergillosis MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Ataxia ADReCS
Atelectasis MetaADEDB
Athetoid SIDER
Athetosis ADReCS
Atrial Fibrillation MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Attempted Suicide MetaADEDB
Automatism MetaADEDB
Autonomic Nervous System Diseases MetaADEDB
Axillary Vein Thrombosis MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacteria Sputum Identified MetaADEDB
Bacteria Urine Identified MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Balance Disorder ADReCS
Basal Ganglia Diseases MetaADEDB
Biliary Dyskinesia MetaADEDB
Biopsy MetaADEDB
Bipolar Disorder MetaADEDB
Birth Defect MetaADEDB
Bladder Neck Operation MetaADEDB
Bleeding Gums MetaADEDB
Bleeding Vaginal MetaADEDB
Blepharoptosis MetaADEDB
Blood Bicarbonate MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Iron Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Abnormal ADReCS
Blood Prolactin Increased MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Operation MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Damage MetaADEDB
Brain Death MetaADEDB
Brain Diseases MetaADEDB
Brain Oedema MetaADEDB
Breast Pain MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchitis MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Bronchospasm ADReCS
Bulbar Palsy MetaADEDB
Bulging MetaADEDB
Cachectic MetaADEDB
Candidiasis Of Mouth MetaADEDB
Candiduria MetaADEDB
Carbon Dioxide Increased ADReCS
Cardiac Arrest ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Operation MetaADEDB
Cardio-Respiratory Arrest ADReCS
Cardioactive Drug Level MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Diseases MetaADEDB
Catalepsy MetaADEDB
Catatonia MetaADEDB
Causalgia MetaADEDB
Central Nervous System Diseases MetaADEDB
Cerebral Aspergillosis MetaADEDB
Cerebral Disorder MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cervicalgia MetaADEDB
Cervicobrachial Syndrome MetaADEDB
Chest Pain MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Choreoathetosis ADReCS
Clonic Convulsion ADReCS
Clonic Movements SIDER
Clonus ADReCS
Cocaine-Related Disorders MetaADEDB
Cognition Disorders MetaADEDB
Coldness SIDER
Colonic Polyp MetaADEDB
Colpitis MetaADEDB
Coma MetaADEDB
Computerised Tomogram MetaADEDB
Confabulation MetaADEDB
Confusion MetaADEDB
Confusional State ADReCS
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipation PROTECT
Continuous Haemodiafiltration MetaADEDB
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Coordination Abnormal MetaADEDB
Cough ADReCS
Crying MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cystatin C Increased MetaADEDB
Cytolytic Hepatitis MetaADEDB
Daydreaming ADReCS
Deafness MetaADEDB
Death ADReCS
Death Sudden Cardiac MetaADEDB
Debridement MetaADEDB
Decreased Interest MetaADEDB
Deep Vein Thromboses MetaADEDB
Deglutition Disorders MetaADEDB
Delayed Emergence From Anesthesia MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Delirium ADReCS
Dental Abscess MetaADEDB
Dental Operation MetaADEDB
Depressed Level Of Consciousness PROTECT
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Seborrheic MetaADEDB
Device Related Infection MetaADEDB
Diabetic Acidosis MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diastolic Dysfunction MetaADEDB
Difficulty Focusing Eyes SIDER
Diplopia ADReCS
Disinhibition ADReCS
Disorders Of Excessive Somnolence MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drooling ADReCS
Drowsiness SIDER
Drug Abuser MetaADEDB
Drug Addict MetaADEDB
Drug Administration Error MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Toxicity MetaADEDB
Dry Mouth PROTECT
Dry Skin MetaADEDB
Dysarthria ADReCS
Dysgeusia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dysphonia ADReCS
Dysphoria ADReCS
Dyspnea MetaADEDB
Dyspnoea ADReCS
Dystonia MetaADEDB
Dystonic Disorders MetaADEDB
Dysuria MetaADEDB
Ear Disorder ADReCS
Ear Tube Insertion MetaADEDB
Eating Disorder MetaADEDB
Echocardiogram Abnormal MetaADEDB
Eczema MetaADEDB
Encephalitis MetaADEDB
Encephalitis Allergic MetaADEDB
Enema Administration MetaADEDB
Enlarged Spleen MetaADEDB
Enterocolitis MetaADEDB
Epidermolysis MetaADEDB
Epilepsies Myoclonic MetaADEDB
Epilepsy MetaADEDB
Epilepsy Tonic-Clonic MetaADEDB
Erectile Dysfunction MetaADEDB
Erythema ADReCS
Euphoric Mood ADReCS
Eustachian Tube Disorder MetaADEDB
Excoriation MetaADEDB
Extrasystoles ADReCS
Extremity Necrosis MetaADEDB
Extremity Pain MetaADEDB
Eye Swelling MetaADEDB
Eyelid Disorder ADReCS
Facial Palsy MetaADEDB
Faecaloma MetaADEDB
Faeces Discoloured MetaADEDB
Fall PROTECT
Fasciculation MetaADEDB
Fatigue PROTECT
Feeding Disorder MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold ADReCS
Felt Faint SIDER
Foot Amputation MetaADEDB
Formication MetaADEDB
Fracture PROTECT
Gagging SIDER
Galactorrhea MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Perforation MetaADEDB
Gastrointestinal Toxicity MetaADEDB
General Physical Health Deterioration MetaADEDB
Gingival Erythema MetaADEDB
Gingival Oedema MetaADEDB
Gingival Pain MetaADEDB
Granuloma MetaADEDB
Grip Strength MetaADEDB
Gynaecomastia MetaADEDB
Haematemesis MetaADEDB
Haematoma ADReCS
Haemodynamic Instability MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Diseases MetaADEDB
Heart Rate Increased MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Lesion MetaADEDB
Hepatocellular Injury MetaADEDB
Herpes Simplex MetaADEDB
Hiccup MetaADEDB
Hiccups ADReCS
Histiocytosis Haematophagic MetaADEDB
Hostility PROTECT
Hydrocele MetaADEDB
Hyperacusia MetaADEDB
Hyperalgesia MetaADEDB
Hypercapnia ADReCS
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hyperventilation ADReCS
Hypoaesthesia MetaADEDB
Hypopnoea ADReCS
Hypotension ADReCS
Hypotensive SIDER
Hypothyroid MetaADEDB
Hypoventilation ADReCS
Hypovolaemia MetaADEDB
Hypoxia ADReCS
Immunoglobulins Abnormal MetaADEDB
Impaired Healing MetaADEDB
Impulsive Behaviour MetaADEDB
Incontinence MetaADEDB
Increased White Blood Cell Count MetaADEDB
Induration ADReCS
Infection MetaADEDB
Influenza Like Illness MetaADEDB
Infusion Related Reaction MetaADEDB
Injection Site Coldness ADReCS
Injection Site Pain ADReCS
Injection Site Rash ADReCS
Injection Site Warmth ADReCS
Insomnia ADReCS
Intervertebral Disc Herniation MetaADEDB
Intestinal Infarction MetaADEDB
Intracranial Hypertension MetaADEDB
Intraoperative Complications MetaADEDB
Intubation MetaADEDB
Ischaemia MetaADEDB
Ischaemic Stroke MetaADEDB
Jaw Operation MetaADEDB
Joint Sprain MetaADEDB
Kidney Failure MetaADEDB
Laryngospasm ADReCS
Learning Disorders MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Lethargy ADReCS
Leukopenia Neonatal MetaADEDB
Life Expectancy Shortened MetaADEDB
Local Swelling MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Lyell MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Mean Arterial Pressure ADReCS
Mean Cell Volume Decreased MetaADEDB
Mechanical Ventilation MetaADEDB
Memory Disorders MetaADEDB
Meningitis Bacterial MetaADEDB
Menstrual Disorder MetaADEDB
Mental Disorder SIDER
Mental Disorders MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Vascular Insufficiency MetaADEDB
Metastases To Abdominal Cavity MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Meninges MetaADEDB
Metastases To Spine MetaADEDB
Micturition Urgency MetaADEDB
Middle Ear Effusion MetaADEDB
Miosis ADReCS
Mood Swings ADReCS
Mouth Pain MetaADEDB
Movement Disorder PROTECT
Mucosal Inflammation MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Stiffness SIDER
Muscle Twitching ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Pain MetaADEDB
Musculoskeletal Stiffness ADReCS
Myoclonus MetaADEDB
Myringotomy MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Necrosis ADReCS
Neonatal Oversedation ADReCS
Nephrolithiasis MetaADEDB
Nervous System Disorder SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neurodegenerative Diseases MetaADEDB
Neurologic Manifestations MetaADEDB
Neuropathy Peripheral ADReCS
Neutropenic Infection MetaADEDB
Neutropenic Sepsis MetaADEDB
Nightmare ADReCS
No Therapeutic Response MetaADEDB
Nodal Rhythm ADReCS
Nuclear Magnetic Resonance Imaging MetaADEDB
Nutritional Condition Abnormal MetaADEDB
Nystagmus ADReCS
Obstruction ADReCS
Obstructive Airways Disorder ADReCS
Oedema Mouth MetaADEDB
Open Wound MetaADEDB
Oral Cavity Fistula MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteoarthritis ADReCS
Osteomyelitis MetaADEDB
Osteosarcoma Metastatic MetaADEDB
Overdose MetaADEDB
Oversedation SIDER
Oxygen Saturation Decreased ADReCS
Pain ADReCS
Pain During Injection SIDER
Pain Postoperative MetaADEDB
Paradoxical Drug Reaction ADReCS
Paraesthesia ADReCS
Paraesthesia Oral MetaADEDB
Perinephric Abscess MetaADEDB
Periodontitis MetaADEDB
Peripheral Ischaemia MetaADEDB
Persistent Foetal Circulation MetaADEDB
Personality Disorders MetaADEDB
Phlebitis ADReCS
Phobia MetaADEDB
Physical Assault PROTECT
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pms MetaADEDB
Pneumothorax MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Vomiting MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Presyncope ADReCS
Procedural Complication MetaADEDB
Procedural Pain MetaADEDB
Proctalgia MetaADEDB
Prostate Cancer Recurrent MetaADEDB
Pruritus ADReCS
Psoriasis MetaADEDB
Psychomotor Agitation MetaADEDB
Psychomotor Disorders MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorders MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Radiation Injury MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Pulse Abnormal ADReCS
Pupils Pinpoint SIDER
Purulent Discharge MetaADEDB
Rash ADReCS
Redness SIDER
Reflex Abnormal MetaADEDB
Renal Tubular Acidosis MetaADEDB
Respiration Abnormal ADReCS
Respiration Disorders MetaADEDB
Respiratory Arrest ADReCS
Respiratory Depression ADReCS
Respiratory Disorder ADReCS
Respiratory Distress Syndrome Newborn MetaADEDB
Respiratory Failure ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Decreased ADReCS
Respiratory Rate Increased MetaADEDB
Respiratory Tract Diseases MetaADEDB
Restlessness ADReCS
Retching ADReCS
Retrograde Amnesia ADReCS
Rhabdomyolysis MetaADEDB
Rhinitis MetaADEDB
Rhinorrhoea ADReCS
Rhonchi ADReCS
Rib Fracture MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Sedation ADReCS
Seizures SIDER
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Sequestrectomy MetaADEDB
Serotonin Syndrome MetaADEDB
Shallow Breathing SIDER
Shock ADReCS
Sinus Bradycardia MetaADEDB
Sinusitis MetaADEDB
Skin Burning Sensation ADReCS
Skin Exfoliation ADReCS
Skin Laceration MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis ADReCS
Sleep Disorder ADReCS
Sleep Disorders MetaADEDB
Sleep Disturbance SIDER
Sleep Initiation And Maintenance Disorders MetaADEDB
Slurred Speech SIDER
Sneezing ADReCS
Snoring MetaADEDB
Somnolence ADReCS
Spinal Column Stenosis MetaADEDB
Spinal Disorder MetaADEDB
Splenic Infarction MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stiffness SIDER
Strabismus ADReCS
Stress Incontinence MetaADEDB
Stridor ADReCS
Substance Withdrawal Syndrome MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Swelling ADReCS
Syncope ADReCS
Syncope Vasovagal ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tachypnoea ADReCS
Tenderness ADReCS
Tendinitis MetaADEDB
Tension ADReCS
Tetanus MetaADEDB
Therapeutic Response Decreased ADReCS
Thrombophlebitis ADReCS
Thyroid Cancer MetaADEDB
Tooth Extraction MetaADEDB
Toothache ADReCS
Torsade De Pointes MetaADEDB
Tranquillisation Excessive SIDER
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Tubulointerstitial Nephritis MetaADEDB
Unconsciousness MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Airway Obstruction ADReCS
Urethral Dilatation MetaADEDB
Urethral Fistula MetaADEDB
Urinary Tract Operation MetaADEDB
Urine Analysis MetaADEDB
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Vascular Diseases MetaADEDB
Vasodilatation PROTECT
Ventricular Bigeminy SIDER
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Premature Complexes MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Loss MetaADEDB
Welts SIDER
Wheezing ADReCS
Withdrawal Syndrome ADReCS
Wrong Technique In Drug Usage Process MetaADEDB
Yawning ADReCS

InAADR: Drug-Protein-ADRs database