| Drug Name: | Mebendazole (31431-39-7) |
|---|---|
| PubChem ID: | 4030 |
| SMILES: | COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3 |
| InchiKey: | OPXLLQIJSORQAM-UHFFFAOYSA-N |
| Therapeutic Category: | Anthelmintics, Anti-Infective Agents, Antimitotic Agents, Antinematodal Agents, Antiparasitic Agents, Mitosis Modulators, Tubulin Modulators |
| Molecular Weight (dalton) | : | 295.298 |
| LogP | : | 2.9722 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 84.08 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Metronidazole (443-48-1) | Epidermal Necrolysis | Additive | The reason for this interaction is not understood, but it appears to be established. Concurrent use should be avoided or very well monitored | Outbreak of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with mebendazole and metronidazole use among Filipino laborers in Taiwan |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category