InAADR

Drug Information

Drug Name: Loxoprofen (68767-14-6)
PubChem ID: 3965
SMILES: CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O
InchiKey: YMBXTVYHTMGZDW-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anti-Inflammatory Agents, Antirheumatic Agents, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 246.306
LogP: 2.7864
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 54.37

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abscess Bacterial MetaADEDB
Acidosis MetaADEDB
Acne MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alopecia MetaADEDB
Altered State Of Consciousness MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anal Abscess MetaADEDB
Androgen Deficiency MetaADEDB
Anorexia MetaADEDB
Anuria MetaADEDB
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Arrhythmia MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriospasm Coronary MetaADEDB
Arteriovenous Fistula MetaADEDB
Arthritis Rheumatoid MetaADEDB
Ascites MetaADEDB
Aseptic Meningitis MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrophy MetaADEDB
Autoimmune Hepatitis MetaADEDB
Automatism MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basophil Count Increased MetaADEDB
Behcet Syndrome MetaADEDB
Bence Jones Protein Urine MetaADEDB
Black Stools MetaADEDB
Bladder Cancer MetaADEDB
Bladder Cancer Recurrent MetaADEDB
Bleb MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Cholesterol Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Depression MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia MetaADEDB
Brain Contusion MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Cancer Pain MetaADEDB
Candida Pneumonia MetaADEDB
Carcinoma Of Prostate MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cataract MetaADEDB
Catheterisation Cardiac MetaADEDB
Cerebral Infarct MetaADEDB
Cervical Myelopathy MetaADEDB
Cervical Vertebral Fracture MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Chronic Myeloid Leukaemia Transformation MetaADEDB
Clostridium Colitis MetaADEDB
Cmv Infection MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat MetaADEDB
Colon Adenoma MetaADEDB
Colorectal Cancer MetaADEDB
Concomitant Disease Progression MetaADEDB
Condition Aggravated MetaADEDB
Contralateral Breast Cancer MetaADEDB
Corneal Epithelium Disorder MetaADEDB
Coronary Angioplasty MetaADEDB
Coronary Artery Restenosis MetaADEDB
Cough MetaADEDB
Coughing Blood MetaADEDB
Craniotomy MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Csf Protein MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Delusion MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressive Symptom MetaADEDB
Dermal Cyst MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Diabetes MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drowsiness MetaADEDB
Dry Skin MetaADEDB
Dysgeusia MetaADEDB
Eating Disorder MetaADEDB
Eczema MetaADEDB
Electrocardiogram P Wave Abnormal MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Electrocardiogram St-T Segment Abnormal MetaADEDB
Encephalitis MetaADEDB
Encephalitis Herpes MetaADEDB
Endoscopy Abnormal MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Pneumonia Chronic MetaADEDB
Epididymitis MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Excess Potassium MetaADEDB
Exercise Electrocardiogram Abnormal MetaADEDB
Exercise Test Abnormal MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Necrosis MetaADEDB
Eye Luxation MetaADEDB
Eyelids Pruritus MetaADEDB
Femur Fracture MetaADEDB
Fungal Disease MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Antral Vascular Ectasia MetaADEDB
Gastric Cancer MetaADEDB
Gastric Ulcer MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Perforation MetaADEDB
Generalised Erythema MetaADEDB
Gingival Erythema MetaADEDB
Glioblastoma Multiforme MetaADEDB
Glucose Urine MetaADEDB
Granuloma MetaADEDB
Haematochezia MetaADEDB
Haemodialysis MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Hematoma Subdural MetaADEDB
Hemiplegia MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatosplenomegaly MetaADEDB
Herpes Simplex Serology Positive MetaADEDB
Herpes Zoster MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hordeolum MetaADEDB
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypokinesia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infected Epidermal Cyst MetaADEDB
Influenza Like Illness MetaADEDB
Injection Site Erythema MetaADEDB
Intensive Care MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Discitis MetaADEDB
Intestinal Obstruction MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intracardiac Thrombus MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Joint Contracture MetaADEDB
Jra MetaADEDB
Kidney Fibrosis MetaADEDB
Large Intestinal Ulcer MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leukopenia Neonatal MetaADEDB
Libido Increased MetaADEDB
Lipase MetaADEDB
Lipodystrophy Acquired MetaADEDB
Long Qt Syndrome MetaADEDB
Lumbar Vertebral Fracture MetaADEDB
Lung Abscess MetaADEDB
Lung Squamous Cell Carcinoma Stage Unspecified MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Macula Lutea Degeneration MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Meningitis Viral MetaADEDB
Metastases To Lung MetaADEDB
Methicillin-Resistant Staphylococcal Aureus Test MetaADEDB
Mouth Ulcer MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myelitis MetaADEDB
Myoglobin Blood Present MetaADEDB
Myringitis MetaADEDB
Nasopharyngitis MetaADEDB
Neoplasm Progression MetaADEDB
Nephrogenic Anaemia MetaADEDB
Nephrotic Syndrome MetaADEDB
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neurological Examination Abnormal MetaADEDB
Neuromyelitis Optica MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutrophil Count Decreased MetaADEDB
No Therapeutic Response MetaADEDB
Non-Small Cell Lung Cancer MetaADEDB
Oedema Mucosal MetaADEDB
Oliguria MetaADEDB
Optic Nerve Disorder MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Osteomyelitis MetaADEDB
Ovarian Cancer MetaADEDB
Pain Exacerbated MetaADEDB
Painful Respiration MetaADEDB
Paraplegia MetaADEDB
Paronychia MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Periarthritis MetaADEDB
Peritonitis MetaADEDB
Persecutory Delusion MetaADEDB
Pharyngeal Abscess MetaADEDB
Pharyngolaryngeal Discomfort MetaADEDB
Platelet Count MetaADEDB
Pleocytosis MetaADEDB
Pleural Effusion MetaADEDB
Pleural Infection MetaADEDB
Pleurisy MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pneumonia Cryptococcal MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Poriomania MetaADEDB
Post Procedural Infection MetaADEDB
Posture Abnormal MetaADEDB
Productive Cough MetaADEDB
Protein Total Decreased MetaADEDB
Psychiatric Symptom MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Infarction MetaADEDB
Purulent Discharge MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Radiation Pneumonitis MetaADEDB
Renal Hypertrophy MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Renal Tubular Necrosis MetaADEDB
Residual Urine MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Failure MetaADEDB
Rhabdomyolysis MetaADEDB
Shock Haemorrhagic MetaADEDB
Shunt Malfunction MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinoatrial Block MetaADEDB
Sinus Arrest MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Test Positive MetaADEDB
Small Intestine Ulcer MetaADEDB
Speech Disorder MetaADEDB
Spinal Compression Fracture MetaADEDB
Splenic Neoplasm Malignancy Unspecified MetaADEDB
Sputum Retention MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subdural Haematoma Evacuation MetaADEDB
Sudden Death MetaADEDB
Sympathicotonia MetaADEDB
Tetany MetaADEDB
Troponin T MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Ulna Fracture MetaADEDB
Unresponsive To Verbal Stimuli MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Uraemic Encephalopathy MetaADEDB
Urticaria Generalised MetaADEDB
Uterine Cancer MetaADEDB
Valvuloplasty Cardiac MetaADEDB
Viral Rash MetaADEDB
Vocal Cord Paralysis MetaADEDB

InAADR: Drug-Protein-ADRs database