| Drug Name: | Lorazepam (846-49-1) |
|---|---|
| PubChem ID: | 3958 |
| SMILES: | C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl |
| InchiKey: | DIWRORZWFLOCLC-UHFFFAOYSA-N |
| Therapeutic Category: | Anti-Anxiety Agents, Anticonvulsants, Antiemetics, Autonomic Agents, Central Nervous System Agents, Central Nervous System Depressants, GABA Agents, GABA Modulators, Gastrointestinal Agents, Hypnotics and Sedatives, Neurotransmitter Agents, Peripheral Nervous System Agents, Psychotropic Drugs, Tranquilizing Agents |
| Molecular Weight (dalton) | : | 321.163 |
| LogP | : | 3.1013 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 61.69 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Mizolastine (108612-45-9) | Amnesia | Synergistic | antihistamines cause sedation, and this would be expected to be increased by some of the benzodiazepines by the simple addition of their CNS depressant effects | Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers |
| Mizolastine (108612-45-9) | Sedation | Synergistic | antihistamines cause sedation, and this would be expected to be increased by some of the benzodiazepines by the simple addition of their CNS depressant effects | Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category