InAADR

Drug Information

Drug Name: Levofloxacin (100986-85-4)
PubChem ID: 149096
SMILES: C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
InchiKey: GSDSWSVVBLHKDQ-JTQLQIEISA-N
Therapeutic Category: Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 361.373
LogP: 1.544
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 75.01

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Amiodarone (1951-25-3) Torsade De Pointes Additive Not established Quinolone-induced QT interval prolongation: a not-so-unexpected class effect
Warfarin (81-81-2) Bleeding Antagonistic Uncertain. It is not clear what factors might have been responsible in those cases where the effects of the anticoagulants were increased Adverse reaction reporting of interaction between warfarin and fluoroquinolones

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abnormal Gait ADReCS
Ageusia ADReCS
Agitation ADReCS
Allergic Reaction ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angioedema ADReCS
Anorexia ADReCS
Anosmia ADReCS
Anxiety ADReCS
Aplastic Anaemia ADReCS
Arthralgia ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Bone Pain ADReCS
Bullous Eruption ADReCS
Candidiasis ADReCS
Cardiac Arrest ADReCS
Cataract ADReCS
Chest Pain ADReCS
Confusional State ADReCS
Conjunctival Oedema ADReCS
Constipation ADReCS
Convulsion ADReCS
Corneal Erosion ADReCS
Depression ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Dizziness ADReCS
Dreaming Abnormal ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Electrocardiogram Qt Prolonged ADReCS
Electroencephalogram Abnormal ADReCS
Encephalopathy ADReCS
Eosinophilia ADReCS
Epistaxis ADReCS
Erythema Multiforme ADReCS
Eye Infection ADReCS
Eye Pain ADReCS
Eyelid Disorder ADReCS
Eyelid Oedema ADReCS
Gastritis ADReCS
Gastroenteritis ADReCS
Genital Candidiasis ADReCS
Glossitis ADReCS
Granulocytopenia ADReCS
Haemolytic Anaemia ADReCS
Hallucination ADReCS
Headache ADReCS
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hyperaemia ADReCS
Hyperglycaemia ADReCS
Hyperkalaemia ADReCS
Hyperkinesia ADReCS
Hypertonia ADReCS
Hypoacusis ADReCS
Hypoglycaemia ADReCS
Infection ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
Instillation Site Irritation ADReCS
Jaundice ADReCS
Lenticular Opacities ADReCS
Leukocytoclastic Vasculitis ADReCS
Leukopenia ADReCS
Multi-Organ Failure ADReCS
Muscle Enzyme Increased ADReCS
Myalgia ADReCS
Myasthenia Gravis ADReCS
Nausea ADReCS
Nightmare ADReCS
Oedema ADReCS
Oesophagitis ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Pancytopenia ADReCS
Paraesthesia ADReCS
Paranoia ADReCS
Parosmia ADReCS
Peripheral Sensory Neuropathy ADReCS
Phlebitis ADReCS
Photosensitivity Reaction ADReCS
Pneumonitis Hypersensitivity ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Pseudomembranous Colitis ADReCS
Psychotic Disorder ADReCS
Pyrexia ADReCS
Rash ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Rhabdomyolysis ADReCS
Scotoma ADReCS
Serum Sickness ADReCS
Sleep Disorder ADReCS
Somnolence ADReCS
Stevens-Johnson Syndrome ADReCS
Stomatitis ADReCS
Suicidal Ideation ADReCS
Suicide Attempt ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tendon Rupture ADReCS
Tendonitis ADReCS
Throat Irritation ADReCS
Thrombocytopenia ADReCS
Tinnitus ADReCS
Torsade De Pointes ADReCS
Toxic Epidermal Necrolysis ADReCS
Tremor ADReCS
Tubulointerstitial Nephritis ADReCS
Ulcerative Keratitis ADReCS
Urticaria ADReCS
Vaginal Infection ADReCS
Vasodilatation ADReCS
Ventricular Arrhythmia ADReCS
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Vitreous Floaters ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database