InAADR

Drug Information

Drug Name: Lamivudine (134678-17-4)
PubChem ID: 60825
SMILES: C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N
InchiKey: JTEGQNOMFQHVDC-NKWVEPMBSA-N
Therapeutic Category: Anti-HIV Agents, Anti-Infective Agents, Anti-Retroviral Agents, Antiviral Agents, Enzyme Inhibitors, Nucleic Acid Synthesis Inhibitors, Reverse Transcriptase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 229.261
LogP: -0.5941
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 90.37

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Acid Fast Bacilli Infection MetaADEDB
Acidosis ADReCS
Acidosis Lactic MetaADEDB
Acquired Immune Deficiency Syndrome MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Prerenal Failure MetaADEDB
Addison Disease MetaADEDB
Adenopathy MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Suppression MetaADEDB
Affective Disorder ADReCS
Aggression MetaADEDB
Aids Encephalopathy MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Amniorrhexis ADReCS
Amylase Increased SIDER
Amyotrophy MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylaxis MetaADEDB
Anemia MetaADEDB
Anemia Macrocytic MetaADEDB
Anger MetaADEDB
Angioedema PROTECT
Anisocoria MetaADEDB
Anogenital Warts MetaADEDB
Anorexia ADReCS
Antinuclear Antibody MetaADEDB
Antiphospholipid Syndrome MetaADEDB
Anxiety ADReCS
Aphthous Stomatitis MetaADEDB
Aplasia ADReCS
Aplasia Pure Red Cell ADReCS
Appendicitis MetaADEDB
Arrhythmia MetaADEDB
Arthralgia ADReCS
Arthropod Bite MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Decreased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Assisted Fertilisation ADReCS
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Ataxia MetaADEDB
Atrophy ADReCS
Auricular Swelling ADReCS
B-Cell Lymphoma MetaADEDB
Basal Ganglia Diseases MetaADEDB
Behcet Syndrome MetaADEDB
Bicytopenia MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Breast MetaADEDB
Black Stools MetaADEDB
Blepharoptosis MetaADEDB
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased ADReCS
Blood Bilirubin Increased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Disorder MetaADEDB
Blood Hiv Rna MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Magnesium Increased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Blood Triglycerides Increased ADReCS
Blood Uric Acid MetaADEDB
Blood Zinc Decreased MetaADEDB
Body Fat Disorder ADReCS
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Failure MetaADEDB
Bone Marrow Toxicity MetaADEDB
Bone Marrow Transplant MetaADEDB
Bradycardia MetaADEDB
Brain Stem Haemorrhage MetaADEDB
Breast Enlargement PROTECT
Breast Feeding ADReCS
Breast Lump MetaADEDB
Breath Sounds Abnormal ADReCS
Bronchitis ADReCS
Bruise MetaADEDB
Burkitt Lymphoma MetaADEDB
Burning Mouth Syndrome MetaADEDB
Cachectic MetaADEDB
Calcinosis MetaADEDB
Calculus Urinary MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Mouth MetaADEDB
Capillary Disorder MetaADEDB
Carcinogenicity SIDER
Carcinoma Of The Cervix MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cellulitis Orbital MetaADEDB
Central obesity MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cervical Myelopathy MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Cirrhosis MetaADEDB
Citrobacter Infection MetaADEDB
Coagulation Time Prolonged MetaADEDB
Completed Suicide ADReCS
Confusional State ADReCS
Connective Tissue Disorder SIDER
Contraindication To Medical Treatment MetaADEDB
Convulsion ADReCS
Corneal Oedema MetaADEDB
Coronary Artery Stenosis MetaADEDB
Corynebacterium Sepsis MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Creatine Phosphokinase Increased SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Cryoglobulinaemia MetaADEDB
Cryptococcosis MetaADEDB
Csf Pressure Increased MetaADEDB
Csf Protein MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cushing Syndrome MetaADEDB
Cushingoid MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Oesophagitis MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Dependence MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Depressive Disorder SIDER
Dermatitis ADReCS
Detached Retina MetaADEDB
Diabetes MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Dilatation Atrial MetaADEDB
Discomfort ADReCS
Disease Recurrence MetaADEDB
Dislocation MetaADEDB
Dizziness ADReCS
Drug Eruptions MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Resistance MetaADEDB
Drug Tolerance MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dyspepsia ADReCS
Dysphasia MetaADEDB
Dysphonia MetaADEDB
Dyspnea MetaADEDB
Dysthymic Disorder ADReCS
Dystonia MetaADEDB
Dysuria MetaADEDB
Ear Disorder ADReCS
Electrolyte Imbalance ADReCS
Elevated Triglycerides MetaADEDB
Emotional Disorder MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
End Stage Liver Disease MetaADEDB
Endocarditis MetaADEDB
Enlarged Spleen MetaADEDB
Enterococcal Infection MetaADEDB
Eosinophilia MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epididymitis MetaADEDB
Erosive Oesophagitis MetaADEDB
Erythema ADReCS
Erythema Multiforme MetaADEDB
Escherichia Sepsis MetaADEDB
Esophageal And Gastric Varices MetaADEDB
Exanthema MetaADEDB
Extrasystoles Ventricular MetaADEDB
Facial Wasting PROTECT
Fanconi Syndrome MetaADEDB
Fat Atrophy MetaADEDB
Fat Redistribution ADReCS
Fatigue ADReCS
Fatty Liver MetaADEDB
Febrile Convulsion MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Femoral Neck Fracture MetaADEDB
Fertilization SIDER
Fever MetaADEDB
Flatulence ADReCS
Folate Deficiency MetaADEDB
Folliculitis MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gas SIDER
Gastric Ulcer MetaADEDB
Gastroenteritis ADReCS
Gastroenteritis Cryptosporidial MetaADEDB
Gastrointestinal Discomfort ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
General Physical Condition MetaADEDB
General Physical Health Deterioration MetaADEDB
Giardiasis MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Membranous MetaADEDB
Glucose Urine MetaADEDB
Goiter MetaADEDB
Granulocyte Count Decreased MetaADEDB
Haemodynamic Instability MetaADEDB
Headache ADReCS
Hearing Loss Bilateral MetaADEDB
Hearing Loss Sensorineural MetaADEDB
Hearing Loss Sudden MetaADEDB
Heart Arrest MetaADEDB
Hemianopia MetaADEDB
Hepatic Cancer Metastatic MetaADEDB
Hepatic Encephalopathy MetaADEDB
Hepatic Enzyme Increased PROTECT
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Insufficiency SIDER
Hepatic Neoplasm Malignant MetaADEDB
Hepatic Steatosis ADReCS
Hepatitis PROTECT
Hepatitis B ADReCS
Hepatitis B Chronic MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis C ADReCS
Hepatitis Fulminant MetaADEDB
Hepatobiliary Disease SIDER
Hepatojugular Reflux MetaADEDB
Hepatomegaly ADReCS
Hepatosplenomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Histoplasmosis Disseminated MetaADEDB
Hiv Disease MetaADEDB
Hiv Infections MetaADEDB
Hiv Seropositivity MetaADEDB
Hiv Wasting Syndrome MetaADEDB
Hiv-Associated Lipodystrophy Syndrome MetaADEDB
Hodgkin Disease MetaADEDB
Hordeolum MetaADEDB
Hypercholesterolaemia PROTECT
Hypercreatininaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperlactacidaemia ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypertensive Cardiomyopathy MetaADEDB
Hypertriglyceridaemia ADReCS
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypocholesterolaemia MetaADEDB
Hypoglycaemia ADReCS
Hypokalaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Ileal Ulcer MetaADEDB
Ill-Defined Disorder ADReCS
Immune Reconstitution Inflammatory Syndrome PROTECT
Immune Reconstitution Syndrome MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Infection In An Immunocompromised Host MetaADEDB
Infection Susceptibility Increased MetaADEDB
Influenza Like Illness MetaADEDB
Insomnia ADReCS
Insufficiency Renal SIDER
Insulin Resistance PROTECT
Interstitial Nephritis MetaADEDB
Intestinal Mucosal Hypertrophy MetaADEDB
Intracranial Hypotension MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Jaundice ADReCS
Kaposi Sarcoma MetaADEDB
Kidney Failure MetaADEDB
Kidney Failure Chronic MetaADEDB
Klebsiella Infection MetaADEDB
Lactic Acidosis ADReCS
Leucopenia MetaADEDB
Leukoencephalomyelitis MetaADEDB
Leukopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Lipase Increased ADReCS
Lipids Increased MetaADEDB
Lipodystrophy Acquired PROTECT
Lipohypertrophy PROTECT
Lipomatosis MetaADEDB
Liver Cirrhosis MetaADEDB
Liver Cirrhosis Biliary MetaADEDB
Liver Failure MetaADEDB
Liver Failure Acute MetaADEDB
Liver Function Test Abnormal ADReCS
Logorrhoea MetaADEDB
Long Qt Syndrome MetaADEDB
Lung Neoplasm MetaADEDB
Lymph Node Tuberculosis MetaADEDB
Lymphadenopathy ADReCS
Lymphocyte Count Abnormal MetaADEDB
Lymphocytic Infiltration MetaADEDB
Lymphoma ADReCS
Maculopathy ADReCS
Malaise ADReCS
Malaria MetaADEDB
Mania MetaADEDB
Menopausal Symptoms MetaADEDB
Mesenteric Vein Thrombosis MetaADEDB
Metastases To Abdominal Cavity MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine ADReCS
Mitochondrial Diseases MetaADEDB
Mouth Ulceration ADReCS
Multi-Organ Failure MetaADEDB
Muscle Atrophy ADReCS
Muscle Disorder PROTECT
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Mycobacterium Tuberculosis Infection MetaADEDB
Myopathy ADReCS
Nasal Congestion ADReCS
Nasal Discharge SIDER
Nasal Disorder ADReCS
Nausea ADReCS
Neoplasm Malignant ADReCS
Nephrolithiasis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
Neutrophil Count Decreased MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Opioid-Related Disorders MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Osteonecrosis PROTECT
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Pancreatic Insufficiency MetaADEDB
Pancreatitis ADReCS
Paraesthesia ADReCS
Paranoia MetaADEDB
Paresthesia MetaADEDB
Perianal Abscess MetaADEDB
Pericarditis MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Persecutory Delusion MetaADEDB
Pharyngitis ADReCS
Platelet Count MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Portal Hypertension MetaADEDB
Postoperative Complications MetaADEDB
Pregnancy SIDER
Pregnancy Complications Infectious MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Productive Cough MetaADEDB
Protein-Losing Gastroenteropathy MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pyrexia ADReCS
Radiation Myelopathy MetaADEDB
Raised Liver Function Tests SIDER
Rash ADReCS
Rash Generalised MetaADEDB
Red Cell Aplasia SIDER
Reflux Esophagitis MetaADEDB
Renal Failure ADReCS
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiration Abnormal ADReCS
Respiratory Disorder ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Tract Infection ADReCS
Reticulocyte Count Decreased MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retinitis Pigmentosa ADReCS
Rhabdomyolysis ADReCS
Rhinorrhoea ADReCS
Scab MetaADEDB
Sensory Disturbance MetaADEDB
Sepsis ADReCS
Septic Shock MetaADEDB
Serratia Infection MetaADEDB
Shock Haemorrhagic MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Diseases Vesiculobullous MetaADEDB
Skin Infection ADReCS
Skin Striae MetaADEDB
Sleep Disorder ADReCS
Spinal Cord Diseases MetaADEDB
Splenomegaly ADReCS
Status Epilepticus MetaADEDB
Stomatitis ADReCS
Substance Withdrawal Syndrome MetaADEDB
Suicide SIDER
Suicide Attempt ADReCS
Sweating SIDER
Swelling ADReCS
Syphilis ADReCS
Tachycardia Ventricular MetaADEDB
Taste Disorders MetaADEDB
Tearfulness MetaADEDB
Tenderness ADReCS
Teratogenicity ADReCS
Therapy Non-Responder MetaADEDB
Thoracic Cavity Drainage MetaADEDB
Thoracic Vertebral Fracture MetaADEDB
Throat Sore SIDER
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Tinea Pedis MetaADEDB
Tinea Versicolor MetaADEDB
Tinnitus MetaADEDB
Torsade De Pointes MetaADEDB
Transaminases Increased MetaADEDB
Treatment Noncompliance MetaADEDB
Ulcer ADReCS
Urinary Tract Infection ADReCS
Urine Analysis Abnormal MetaADEDB
Urticaria ADReCS
Vanishing Bile Duct Syndrome MetaADEDB
Vertigo Positional MetaADEDB
Viral Load MetaADEDB
Viremia MetaADEDB
Vomiting ADReCS
Weakness SIDER
Wheezing ADReCS
White Blood Cell Count Abnormal MetaADEDB
Xanthopsia MetaADEDB
Xerostomia MetaADEDB
Zinc Deficiency MetaADEDB

InAADR: Drug-Protein-ADRs database