InAADR

Drug Information

Drug Name: Lacosamide (175481-36-4)
PubChem ID: 219078
SMILES: CC(=O)N[C@H](COC)C(=O)NCC1=CC=CC=C1
InchiKey: VPPJLAIAVCUEMN-GFCCVEGCSA-N
Therapeutic Category: Anticonvulsants, Central Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 250.298
LogP: 0.4539
Ring Count: 1
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 67.43

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Behaviour MetaADEDB
Abnormal Dreams MetaADEDB
Accelerated Hypertension MetaADEDB
Accommodation Disorder MetaADEDB
Acidosis MetaADEDB
Acne MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Aggression ADReCS
Agitated MetaADEDB
Agitation ADReCS
Agranulocytosis PROTECT
Alanine Aminotransferase Increased PROTECT
Alcohol Intoxication SIDER
Alcohol Poisoning ADReCS
Alveolitis Fibrosing MetaADEDB
Anaemia ADReCS
Anger MetaADEDB
Angioedema ADReCS
Anticonvulsant Drug Level MetaADEDB
Anticonvulsant Drug Level Abnormal MetaADEDB
Areflexia MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Atrial Ectopic Beats MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter ADReCS
Atrioventricular Block SIDER
Atrioventricular Block First Degree MetaADEDB
Atrioventricular Block Second Degree MetaADEDB
Attempted Suicide MetaADEDB
Bacterial Test Positive MetaADEDB
Balance Disorder ADReCS
Band Neutrophil Percentage Increased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Urea Increased MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Breast Cellulitis MetaADEDB
Bruise MetaADEDB
Bundle Branch Block Right MetaADEDB
Burning Sensation Mucosal MetaADEDB
Cardiac Disorder ADReCS
Cardiac Fibrillation ADReCS
Cardiac Flutter ADReCS
Cerebellar Syndrome ADReCS
Cerebral Ischaemia MetaADEDB
Cervical Vertebral Fracture MetaADEDB
Cervicalgia MetaADEDB
Chest Pain MetaADEDB
Chromaturia MetaADEDB
Cognitive Disorder ADReCS
Cold Sweat MetaADEDB
Confusional State ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Contusion ADReCS
Convulsions Grand Mal MetaADEDB
Coordination Abnormal PROTECT
Coronary Artery Stenosis MetaADEDB
Crying MetaADEDB
Deja Vu MetaADEDB
Delusional Perception MetaADEDB
Depressed Mood ADReCS
Depression ADReCS
Depression Suicidal MetaADEDB
Dermatitis ADReCS
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disturbance In Attention ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowning MetaADEDB
Drug Dose Omission MetaADEDB
Drug Hypersensitivity ADReCS
Drug Screen Positive MetaADEDB
Dry Mouth ADReCS
Dysarthria ADReCS
Dyspepsia ADReCS
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Ear Discomfort MetaADEDB
Electrocardiogram Pr Prolongation PROTECT
Electrocardiogram St Segment Elevation MetaADEDB
Emesis MetaADEDB
Encephalomalacia MetaADEDB
Encephalopathy MetaADEDB
Erythema ADReCS
Euphoric Mood PROTECT
Eye Disorder SIDER
Face Injury MetaADEDB
Fall ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Feeling Drunk ADReCS
Flank Pain MetaADEDB
Flatulence PROTECT
Floaters MetaADEDB
Food Craving MetaADEDB
Foot Fracture MetaADEDB
Gait Disturbance ADReCS
Gastrointestinal Disorder SIDER
Glioblastoma Multiforme MetaADEDB
Haemorrhage Intracranial MetaADEDB
Hallucination PROTECT
Headache ADReCS
Hematoma Subdural MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis Viral ADReCS
Homicidal Ideation MetaADEDB
Hostility MetaADEDB
Hypersensitivity ADReCS
Hypervigilance MetaADEDB
Hypoaesthesia ADReCS
Hypoaesthesia Oral ADReCS
Immune System Disorder SIDER
Inappropriate Schedule Of Drug Administration MetaADEDB
Incoherent MetaADEDB
Incorrect Dose Administered MetaADEDB
Injection Site Pain ADReCS
Inner Ear Disorder ADReCS
Insomnia ADReCS
Irritability ADReCS
Jaw Fracture MetaADEDB
Labyrinthine Disorder SIDER
Laceration PROTECT
Large For Dates Baby MetaADEDB
Liver Function Test Abnormal ADReCS
Memory Impairment ADReCS
Mental Disorder SIDER
Middle Insomnia MetaADEDB
Mitral Valve Sclerosis MetaADEDB
Moaning MetaADEDB
Mood Altered ADReCS
Mood Swings ADReCS
Muscle Spasms ADReCS
Myoclonic Epilepsy MetaADEDB
Nail Operation MetaADEDB
Nausea ADReCS
Nephritis ADReCS
Nephrolithiasis MetaADEDB
Nervous System Disorder ADReCS
Neutropenia ADReCS
Nightmare MetaADEDB
Nipple Disorder MetaADEDB
Nipple Pain MetaADEDB
No Therapeutic Response MetaADEDB
Nystagmus ADReCS
Ocular Icterus MetaADEDB
Off Label Use MetaADEDB
Optic Neuropathy MetaADEDB
Osteoarthritis ADReCS
Pain ADReCS
Palpitations ADReCS
Panic Attack MetaADEDB
Paraesthesia ADReCS
Paranoia MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Personality Change MetaADEDB
Poisoning ADReCS
Pollakiuria MetaADEDB
Polyhydramnios MetaADEDB
Pregnancy On Contraceptive MetaADEDB
Procedural Complication ADReCS
Protein Urine Present ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Psychoses MetaADEDB
Psychotic Disorder ADReCS
Pulmonary Oedema Neonatal MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Rib Fracture MetaADEDB
Road Traffic Accident MetaADEDB
Self-Injurious Ideation MetaADEDB
Sensation Of Heaviness MetaADEDB
Skin Laceration ADReCS
Snoring MetaADEDB
Somnolence ADReCS
Spinal Osteoarthritis MetaADEDB
Status Epilepticus MetaADEDB
Suicidal Behaviour MetaADEDB
Suicidal Ideation PROTECT
Suicide Attempt PROTECT
Supraventricular Tachycardia MetaADEDB
Suspiciousness MetaADEDB
Swollen Tongue MetaADEDB
Syncope PROTECT
Tangentiality MetaADEDB
Tearfulness MetaADEDB
Tinnitus ADReCS
Traumatic Fracture MetaADEDB
Tremor ADReCS
Type Iv Hypersensitivity Reaction ADReCS
Urinary Sediment Present MetaADEDB
Urticaria ADReCS
Vascular Insufficiency MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Weight Gain MetaADEDB

InAADR: Drug-Protein-ADRs database