InAADR

Drug Information

Drug Name: Ketamine (6740-88-1)
PubChem ID: 3821
SMILES: CNC1(CCCCC1=O)C2=CC=CC=C2Cl
InchiKey: YQEZLKZALYSWHR-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anesthetics, Central Nervous System Agents, Central Nervous System Depressants, Excitatory Amino Acid Agents, Excitatory Amino Acid Antagonists, Neurotransmitter Agents, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 237.73
LogP: 2.8978
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 29.1

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Respiratory Depression Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Infection MetaADEDB
Abdominal infection MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Sepsis MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Lfts MetaADEDB
Abscess MetaADEDB
Abscess Bacterial MetaADEDB
Abuse MetaADEDB
Accident MetaADEDB
Accidental Death MetaADEDB
Acidosis MetaADEDB
Acrochordon MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenitis MetaADEDB
Adenopathy MetaADEDB
Adhesiolysis MetaADEDB
Adrenal Insufficiency MetaADEDB
Adrenal Suppression MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Airway Obstruction Nos SIDER
Alanine Aminotransferase Increased MetaADEDB
Alveoloplasty MetaADEDB
Amnesia MetaADEDB
Amnesia Anterograde MetaADEDB
Anaemia MetaADEDB
Anaemia Postoperative MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angina Pectoris MetaADEDB
Anguish SIDER
Anorexia ADReCS
Anoxia MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Valve Insufficiency MetaADEDB
Apgar Score Low MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Application Site Discolouration MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Ascites Infection MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspergillosis MetaADEDB
Asphyxia MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrophy MetaADEDB
Autoimmune Disorder MetaADEDB
Autoimmune Hepatitis MetaADEDB
Automatism MetaADEDB
Autonomic Instability MetaADEDB
Axillary Vein Thrombosis MetaADEDB
Back Ache MetaADEDB
Bacterial Infections MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Ganglion Degeneration MetaADEDB
Basophilia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Bladder Abnormal MetaADEDB
Birth Trauma MetaADEDB
Bladder Disorder MetaADEDB
Bladder Hypertrophy MetaADEDB
Bladder Inflammation MetaADEDB
Blindness MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Disorder MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Parathyroid Hormone Increased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Increased ADReCS
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Body Temperature MetaADEDB
Bone Density Decreased MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Bradycardia ADReCS
Brain Abscess MetaADEDB
Brain Death MetaADEDB
Brain Diseases MetaADEDB
Brain Injuries MetaADEDB
Brain Ischemia MetaADEDB
Brain Scan Abnormal MetaADEDB
Breast Cancer Stage Ii MetaADEDB
Breath Sounds Abnormal MetaADEDB
Breech Presentation MetaADEDB
Bulging MetaADEDB
Burns MetaADEDB
Caecitis MetaADEDB
Caesarean Section MetaADEDB
Capgras Syndrome MetaADEDB
Capillary Leak Syndrome MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Arrest Neonatal MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Diseases MetaADEDB
Catalepsy MetaADEDB
Catatonia MetaADEDB
Causalgia MetaADEDB
Cellulitis MetaADEDB
Cellulitis Gangrenous MetaADEDB
Central Nervous System Lymphoma MetaADEDB
Cerebral Artery Embolism MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Disorder MetaADEDB
Cervical Discharge MetaADEDB
Chemical Poisoning MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis Chronic MetaADEDB
Cleft Palate MetaADEDB
Clonic Movements SIDER
Clonus ADReCS
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Cognition Disorders MetaADEDB
Coma MetaADEDB
Completed Suicide MetaADEDB
Complications Of Transplanted Liver MetaADEDB
Computerised Tomogram Abdomen Abnormal MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Confusion MetaADEDB
Congenital Infection MetaADEDB
Congenital Pyelocaliectasis MetaADEDB
Constipated MetaADEDB
Contracted Bladder MetaADEDB
Conversion Disorder MetaADEDB
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Coombs Direct Test Positive MetaADEDB
Coronary Artery Stenosis MetaADEDB
Crystal Urine MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyanosis MetaADEDB
Cystitis MetaADEDB
Cystitis Interstitial MetaADEDB
Death Neonatal MetaADEDB
Death Sudden Cardiac MetaADEDB
Decreased Appetite ADReCS
Delayed Fontanelle Closure MetaADEDB
Delirium MetaADEDB
Delusional Disorder Unspecified Type MetaADEDB
Delusional Perception MetaADEDB
Dependence MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressive Disorder MetaADEDB
Depressive Disorder Major MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Diabetes Insipidus MetaADEDB
Dialysis MetaADEDB
Dilatation Intrahepatic Duct Acquired MetaADEDB
Diplopia ADReCS
Disorders Of Excessive Somnolence MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dissociative Disorders MetaADEDB
Diverticulum MetaADEDB
Dizziness MetaADEDB
Drug Abuse ADReCS
Drug Abuser MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Screen Positive MetaADEDB
Drug Toxicity MetaADEDB
Dysphoria ADReCS
Dystonia MetaADEDB
Dysuria MetaADEDB
Economic Problem MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram T Wave Amplitude Decreased MetaADEDB
Electromechanical Dissociation MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Enterococcal Bacteraemia MetaADEDB
Enterococcal Infection MetaADEDB
Epilepsies Myoclonic MetaADEDB
Epilepsy ADReCS
Erythema ADReCS
Escherichia Infection MetaADEDB
Excess Potassium MetaADEDB
Excessive Salivation MetaADEDB
Excessive Thirst MetaADEDB
Expressive Language Disorder MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Inflammation MetaADEDB
Eyelid Ptosis Congenital MetaADEDB
Face Injury MetaADEDB
Facial Pain MetaADEDB
Faecal Impaction MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Fever MetaADEDB
Fibromyalgia MetaADEDB
Fibrosis MetaADEDB
Fine Motor Delay MetaADEDB
Flashback ADReCS
Forced Expiratory Volume Decreased MetaADEDB
Fungal Disease MetaADEDB
Gait Disorders Neurologic MetaADEDB
Gastric Ulcer MetaADEDB
Gastritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Gestational Diabetes MetaADEDB
Gingival Pain MetaADEDB
Glaucoma ADReCS
Granulocytosis MetaADEDB
Gun Shot Wound MetaADEDB
Haemangioma MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haematoma Infection MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobinuria MetaADEDB
Haemolysis MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage Intracranial MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Transformation Stroke MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache MetaADEDB
Heart Arrest MetaADEDB
Heart Injury MetaADEDB
Heart Rate Increased ADReCS
Hematoma Subdural MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatic Siderosis MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatotoxicity MetaADEDB
Hernia Hiatal MetaADEDB
High Arched Palate MetaADEDB
Hip Surgery MetaADEDB
Homicide MetaADEDB
Hydronephrosis MetaADEDB
Hydroureter MetaADEDB
Hyperalgesia MetaADEDB
Hyperglycemia MetaADEDB
Hyperkinesis MetaADEDB
Hyperphosphataemia MetaADEDB
Hypertelorism Of Orbit MetaADEDB
Hypertension MetaADEDB
Hypertension Pulmonary MetaADEDB
Hypertonic Bladder MetaADEDB
Hyperviscosity Syndrome MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalemia MetaADEDB
Hypokinesia MetaADEDB
Hypotension ADReCS
Hypotonia Neonatal MetaADEDB
Iliac Artery Stenosis MetaADEDB
Illusion MetaADEDB
Immunosuppression MetaADEDB
Impaired Healing MetaADEDB
Incontinence MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infective Thrombosis MetaADEDB
Injection Site Thrombosis MetaADEDB
Insomnia ADReCS
International Normalised Ratio Increased MetaADEDB
Intracranial Hypertension MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Intravascular Haemolysis MetaADEDB
Intraventricular Haemorrhage Neonatal MetaADEDB
Jra MetaADEDB
Kidney Diseases MetaADEDB
Kidney Failure MetaADEDB
Kidney Small MetaADEDB
Labor Pain MetaADEDB
Laceration MetaADEDB
Laryngeal Dyspnoea MetaADEDB
Laryngismus MetaADEDB
Laryngospasm ADReCS
Learning Disorders MetaADEDB
Lethargy MetaADEDB
Lipase MetaADEDB
Locked-In Syndrome MetaADEDB
Long Qt Syndrome MetaADEDB
Lung Edema MetaADEDB
Lyell MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphocytic Infiltration MetaADEDB
Malignant Melanoma MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mediastinal Haemorrhage MetaADEDB
Memory Disorders MetaADEDB
Mental Disorders MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Disorder MetaADEDB
Metastases To Adrenals MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Ovary MetaADEDB
Metastases To Skin MetaADEDB
Metastatic Renal Cell Carcinoma MetaADEDB
Micturition Urgency MetaADEDB
Milk Allergy MetaADEDB
Mitral Valve Insufficiency MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Mood Disorders MetaADEDB
Mouth Bleeding MetaADEDB
Mucositis MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Injuries MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Disorder MetaADEDB
Muscle Hypotonia MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Twitching ADReCS
Musculoskeletal Discomfort MetaADEDB
Myocardial Fibrosis MetaADEDB
Myoclonus MetaADEDB
Nausea ADReCS
Neck Pain MetaADEDB
Necrosis MetaADEDB
Neonatal Respiratory Distress Syndrome MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Degeneration MetaADEDB
Nervous System Diseases MetaADEDB
Neumonia MetaADEDB
Neuralgia MetaADEDB
Neuralgia Postherpetic MetaADEDB
Neurobehavioral Manifestations MetaADEDB
Neuroblastoma Recurrent MetaADEDB
Neutropenic Colitis MetaADEDB
Neutropenic Sepsis MetaADEDB
Nodule Skin MetaADEDB
Nystagmus ADReCS
Nystagmus Pathologic MetaADEDB
Obstruction ADReCS
Obstructive Airways Disorder ADReCS
Ocular Motility Disorders MetaADEDB
Oesophageal Infection MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Olfaction Disorders MetaADEDB
Oliguria MetaADEDB
Oophorectomy MetaADEDB
Operative Haemorrhage MetaADEDB
Osteoarthritis MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Postoperative MetaADEDB
Papillary Necrosis MetaADEDB
Paresthesia MetaADEDB
Pedal Pulse Absent MetaADEDB
Perceptual Disorders MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Peritonitis Bacterial MetaADEDB
Phlebothrombosis MetaADEDB
Photophobia MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumothorax MetaADEDB
Po2 Decreased MetaADEDB
Poisoning MetaADEDB
Pollakiuria MetaADEDB
Polycythaemia MetaADEDB
Polyneuropathy In Malignant Disease MetaADEDB
Polyuria MetaADEDB
Post Procedural Haematuria MetaADEDB
Postmature Baby MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Pre-Eclampsia MetaADEDB
Premature Baby MetaADEDB
Procedural Complication MetaADEDB
Procedural Hypotension MetaADEDB
Product Quality Issue MetaADEDB
Propofol Infusion Syndrome MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus MetaADEDB
Psychomotor Agitation MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorders MetaADEDB
Pubic Rami Fracture MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Hypertensive Crisis MetaADEDB
Pulmonary Valve Insufficiency MetaADEDB
Pyogenic Granuloma MetaADEDB
Pyuria MetaADEDB
Rales MetaADEDB
Rash ADReCS
Rash Morbilliform ADReCS
Reflex Sympathetic Dystrophy MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Regurgitation Of Food MetaADEDB
Renal Artery Thrombosis MetaADEDB
Renal Function Test Abnormal MetaADEDB
Respiratory Depression ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Respiratory Tract Diseases MetaADEDB
Retroperitoneal Lymphadenopathy MetaADEDB
Rhabdomyolysis MetaADEDB
Risus Sardonicus MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Schizophrenia MetaADEDB
Schizotypal Personality Disorder MetaADEDB
Seizures SIDER
Self-Medication MetaADEDB
Septic Shock MetaADEDB
Shock ADReCS
Skin Turgor Decreased MetaADEDB
Spasm MetaADEDB
Speech Disorders MetaADEDB
Sputum Culture Positive MetaADEDB
Status Asthmaticus MetaADEDB
Status Epilepticus MetaADEDB
Stereotypic Movement Disorder MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stupor MetaADEDB
Subcutaneous Nodule MetaADEDB
Submandibular Mass MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Substance-Related Disorders MetaADEDB
Sudden Death MetaADEDB
Superinfection Bacterial MetaADEDB
Supraventricular Tachycardia MetaADEDB
Surgical Procedure Repeated MetaADEDB
Tachycardia MetaADEDB
Tachycardia Ventricular MetaADEDB
Takotsubo Cardiomyopathy MetaADEDB
Temperature Regulation Disorder MetaADEDB
Thrombophlebitis MetaADEDB
Tooth Development Disorder MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Transfusion-Related Acute Lung Injury MetaADEDB
Tremor MetaADEDB
Trismus MetaADEDB
Tuberculin Test Positive MetaADEDB
Type I Hypersensitivity MetaADEDB
Ulcer MetaADEDB
Unconsciousness MetaADEDB
Upper Limb Fracture MetaADEDB
Urge Incontinence MetaADEDB
Urinary Bladder Diseases MetaADEDB
Urine Phosphate Increased MetaADEDB
Urologic Diseases MetaADEDB
Urosepsis MetaADEDB
Vaginal Cellulitis MetaADEDB
Venoocclusive Disease MetaADEDB
Venoocclusive Liver Disease MetaADEDB
Venous Thrombosis Limb MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Ventricular Premature Complexes MetaADEDB
Vertigo MetaADEDB
Vision Blurred ADReCS
Vision Disorders MetaADEDB
Vitamin D Increased MetaADEDB
Vomiting ADReCS
Withdrawal Syndrome MetaADEDB
Wound Drainage MetaADEDB
Wound Infection MetaADEDB
Wound Secretion MetaADEDB
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database