InAADR

Drug Information

Drug Name: Isradipine (75695-93-1)
PubChem ID: 3784
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC
InchiKey: HMJIYCCIJYRONP-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 371.393
LogP: 2.5822
Ring Count: 2
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 103.55

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abnormal Gait MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Vision MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Actinomycosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Failure MetaADEDB
Acute Sinusitis MetaADEDB
Adhesion MetaADEDB
Adnexa Uteri Cyst MetaADEDB
Adrenal Neoplasm MetaADEDB
Affective Disorder MetaADEDB
Afib MetaADEDB
Agoraphobia MetaADEDB
Agraphia MetaADEDB
Albuminuria ADReCS
Allergic Dermatitis MetaADEDB
Alopecia ADReCS
Alveolitis MetaADEDB
Alveoloplasty MetaADEDB
Amnesia MetaADEDB
Amphetamine-Related Disorders MetaADEDB
Anaemia MetaADEDB
Anaemia Of Malignant Disease MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactoid Reaction ADReCS
Aneurysm MetaADEDB
Angiitis MetaADEDB
Angina Pectoris MetaADEDB
Angioedema ADReCS
Angiopathy MetaADEDB
Anisocoria MetaADEDB
Anorexia MetaADEDB
Anosmia MetaADEDB
Antineutrophil Cytoplasmic Antibody MetaADEDB
Anxiety MetaADEDB
Aortic Valve Sclerosis MetaADEDB
Appetite Disorder ADReCS
Application Site Dermatitis MetaADEDB
Application Site Irritation MetaADEDB
Application Site Pruritus MetaADEDB
Aptyalism MetaADEDB
Areflexia MetaADEDB
Arrhythmia MetaADEDB
Arrhythmia Supraventricular MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriovenous Fistula Occlusion MetaADEDB
Arteriovenous Fistula Thrombosis MetaADEDB
Arthralgia ADReCS
Arthritis Infective MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthroscopy MetaADEDB
Aspergillosis MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Ataxia MetaADEDB
Atherosclerosis MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block First Degree MetaADEDB
Automatism MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Back Disorder MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bacteria Tissue Specimen Identified MetaADEDB
Bacterial Test Positive MetaADEDB
Bad Breath MetaADEDB
Balance Disorder MetaADEDB
Basal Cell Carcinoma MetaADEDB
Basedow Disease MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Tract Disorder MetaADEDB
Biopsy MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bleeding Gums MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Electrolytes Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Magnesium Increased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Fibrosis MetaADEDB
Bone Operation MetaADEDB
Bone Pain MetaADEDB
Bone Spur MetaADEDB
Bone Swelling MetaADEDB
Bone Trimming MetaADEDB
Bradycardia MetaADEDB
Brain Ischemia MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer MetaADEDB
Breast Cancer In Situ MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Right MetaADEDB
Burning Sensation MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis MetaADEDB
Cachectic MetaADEDB
Candida Infection MetaADEDB
Capillary Leak Syndrome MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Pacemaker Insertion MetaADEDB
Cardiac Stress Test Abnormal MetaADEDB
Cardiomyopathy MetaADEDB
Cardiomyopathy Hypertrophic MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cataract MetaADEDB
Cataract Cortical MetaADEDB
Cataract Operation MetaADEDB
Catheter Placement MetaADEDB
Central Line Infection MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebellar Infarction MetaADEDB
Cervical Cord Compression MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Choroiditis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Coated Tongue MetaADEDB
Cocaine-Related Disorders MetaADEDB
Compression Fracture MetaADEDB
Computerised Tomogram MetaADEDB
Condition Aggravated MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy ADReCS
Constipated MetaADEDB
Constipation ADReCS
Coronary Artery Bypass MetaADEDB
Coronary Disease MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Cramps Leg ADReCS
Crying MetaADEDB
Cutaneous Sarcoidosis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness ADReCS
Deafness Bilateral MetaADEDB
Deafness Congenital MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Decreased Libido MetaADEDB
Decubitus Ulcer MetaADEDB
Deep Vein Thromboses MetaADEDB
Dehydration MetaADEDB
Delayed Sleep Phase MetaADEDB
Dental Examination MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Denture Wearer MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Dermatitides MetaADEDB
Dermatitis Exfoliative ADReCS
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Foot MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Disease Progression MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Disturbance In Attention MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dna Antibody Positive MetaADEDB
Drug Effect Delayed MetaADEDB
Drug Fever ADReCS
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer Haemorrhage MetaADEDB
Duodenal Ulcer Perforation MetaADEDB
Dysarthria MetaADEDB
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Early Morning Awakening MetaADEDB
Economic Problem MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Corrected Interval MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Emesis MetaADEDB
Epidermal Necrosis ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Eruption MetaADEDB
Erythema MetaADEDB
Erythema Migrans MetaADEDB
Erythema Multiforme ADReCS
Excessive Granulation Tissue MetaADEDB
Excessive Thirst MetaADEDB
Excoriation MetaADEDB
Extrasystoles Ventricular MetaADEDB
Faecaloma MetaADEDB
Faeces Discoloured MetaADEDB
Failure To Thrive MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Female Sexual Arousal Disorder ADReCS
Fib MetaADEDB
Flatulence MetaADEDB
Flushing ADReCS
Focal Glomerulosclerosis MetaADEDB
Foot Deformity MetaADEDB
Fungal Disease MetaADEDB
Gammopathy MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastric Ulcer Perforated MetaADEDB
Gastric Ulcer Surgery MetaADEDB
Gastrointestinal Disorder ADReCS
Gingival Pain MetaADEDB
Gout MetaADEDB
Graft Versus Host Disease MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia MetaADEDB
Haematochezia MetaADEDB
Haemorrhagic Transformation Stroke MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Failure MetaADEDB
Heart Rate Increased MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatotoxicity ADReCS
Hyperaesthesia MetaADEDB
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hyperosmolar State MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperpigmentation MetaADEDB
Hyperplasia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive Heart Disease MetaADEDB
Hypertriglyceridaemia ADReCS
Hyperviscosity Syndrome MetaADEDB
Hypoaesthesia MetaADEDB
Hypokalaemia ADReCS
Hypomagnesaemia MetaADEDB
Hyporeflexia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Ild MetaADEDB
Immunoglobulins Abnormal MetaADEDB
Impaired Healing MetaADEDB
Impotence ADReCS
Infection Urinary Tract MetaADEDB
Injection Site Erythema MetaADEDB
Insomnia ADReCS
International Normalised Ratio Increased MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Space Narrowing MetaADEDB
Intestinal Diseases MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Itch MetaADEDB
Jaw Operation MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Joint Sprain MetaADEDB
Kidney Failure MetaADEDB
Kidney Neoplasm MetaADEDB
Left Atrial Dilatation MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leg Pain ADReCS
Legionella MetaADEDB
Lethargy ADReCS
Leukocytoclastic Vasculitis ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Lip Ulceration MetaADEDB
Liver Function Test Abnormal ADReCS
Long Qt Syndrome MetaADEDB
Loss Of Weight MetaADEDB
Lower Limb Fracture MetaADEDB
Lung Fibrosis MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Medical Device Complication MetaADEDB
Medication Residue MetaADEDB
Meningeal Neoplasm MetaADEDB
Menstrual Disorder ADReCS
Metabolic Syndrome MetaADEDB
Metamorphopsia MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Monoclonal Immunoglobulin Present MetaADEDB
Monoplegia MetaADEDB
Motor Retardation MetaADEDB
Mouth Ulcer MetaADEDB
Movement Disorders MetaADEDB
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Spasms ADReCS
Muscle Swelling MetaADEDB
Muscle Tightness MetaADEDB
Muscle Weakness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Musculoskeletal Pain MetaADEDB
Musculoskeletal Stiffness ADReCS
Mutism MetaADEDB
Myalgia ADReCS
Mycobacterial Infection MetaADEDB
Myocardial Infarction ADReCS
Nail Bed Infection MetaADEDB
Nasal Congestion ADReCS
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nervousness ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
Neutrophilia MetaADEDB
Nocturia ADReCS
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oral Infection MetaADEDB
Oral Soft Tissue Disorder MetaADEDB
Oral Surgery MetaADEDB
Oropharyngeal Pain ADReCS
Orthostatic Hypotension ADReCS
Osteoarthritis MetaADEDB
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Osteoradionecrosis MetaADEDB
Osteosclerosis MetaADEDB
Pain In Extremity ADReCS
Pallor MetaADEDB
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Paraesthesia ADReCS
Paranoia MetaADEDB
Parathyroid Tumour Benign MetaADEDB
Pericarditis Uraemic MetaADEDB
Periodontal Disease MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Peritoneal Effusion MetaADEDB
Pharyngitis Streptococcal MetaADEDB
Photosensitivity Reaction ADReCS
Pigmentation Disorder MetaADEDB
Pleural Effusion MetaADEDB
Pneumoperitoneum MetaADEDB
Pollakiuria ADReCS
Polyhydramnios MetaADEDB
Poor Dental Condition MetaADEDB
Prostatism MetaADEDB
Proteinuria MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psoriasis MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Thrombosis MetaADEDB
Purulent Discharge MetaADEDB
Pyrexia ADReCS
Qrs Axis Abnormal MetaADEDB
Radicular Syndrome MetaADEDB
Rash ADReCS
Refusal Of Treatment By Patient MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Cyst MetaADEDB
Renal Failure Neonatal MetaADEDB
Renal Hypertrophy MetaADEDB
Renal Injury MetaADEDB
Renal Mass MetaADEDB
Retinal Vascular Occlusion MetaADEDB
Retinal Vein Thrombosis MetaADEDB
Rhinorrhea MetaADEDB
Road Traffic Accident MetaADEDB
Salivary Gland Inflammation MetaADEDB
Scar MetaADEDB
Scotoma MetaADEDB
Sensation Of Foreign Body MetaADEDB
Sensation Of Heaviness MetaADEDB
Serositis MetaADEDB
Serum Sickness ADReCS
Sick Sinus Syndrome MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Laceration MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Sleep Apnea MetaADEDB
Small Bowel Angioedema MetaADEDB
Somnolence ADReCS
Spinal Column Stenosis MetaADEDB
Spinal Disorder MetaADEDB
Spinal Osteoarthritis MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress Incontinence MetaADEDB
Stress Symptoms MetaADEDB
Stroke ADReCS
Subcutaneous Abscess MetaADEDB
Subcutaneous Emphysema MetaADEDB
Supraventricular Tachycardia MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Temporomandibular Joint Syndrome MetaADEDB
Tendon Disorder MetaADEDB
Therapeutic Response Decreased MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Throat Tightness MetaADEDB
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Thyroid Cyst MetaADEDB
Tinea MetaADEDB
Tinnitus ADReCS
Tongue Dry MetaADEDB
Tongue Injury MetaADEDB
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Transient Ischaemic Attack ADReCS
Tricuspid Valve Sclerosis MetaADEDB
Troponin Increased MetaADEDB
Urticaria ADReCS
Vasculitis ADReCS
Vasospasm Intracranial MetaADEDB
Ventricular Fibrillation ADReCS
Vertigo ADReCS
Violence-Related Symptom MetaADEDB
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Decreased ADReCS
Weight Fluctuation MetaADEDB
Weight Gain MetaADEDB
Weight Increased ADReCS
Wound Dehiscence MetaADEDB
Wound Infection Staphylococcal MetaADEDB

InAADR: Drug-Protein-ADRs database